Ophthalmology

The AJMC^® Ophthalmology compendium is a comprehensive resource for clinical news and expert insights for treatment of disorders of the eye.

Latest News

Screening for AMD | Image credit: RFBSIP - stock.adobe.com

Short-Term Improvements Seen in Patients With nAMD Switching to Faricimab

By Julia Bonavitacola

May 1st 2025

Patients with neovascular age-related macular degeneration (nAMD) experienced improvements in central macular thickness and subretinal and intraretinal fluid after switching.

Vision test | Image credit: Miroslav110 - stock.adobe.com

FDA Delivers CRL for Longer Dosage Intervals in Aflibercept for DME, Wet AMD

By Julia Bonavitacola

April 21st 2025

Man rubbing his eyes | Image credit: Prostock-studio - stock.adobe.com

Sleep Disruptions Contribute to Likelihood of Dry Eye Syndrome

By Julia Bonavitacola

April 9th 2025

Dry eye | Image credit: Kryuchka Yaroslav - stock.adobe.com

Reproxalap Receives Complete Response Letter From FDA for Use in Dry Eye Disease

By Julia Bonavitacola

April 3rd 2025

Astigmatism | Image credit: Zarina Lukash - stock.adobe.com

Prevalence, Severity of Astigmatism Increased in Children After Pandemic

By Julia Bonavitacola

March 26th 2025

Continuing Medical Education

Application of Recent Data in Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema: Managed Care Insights and Strategies

1.5 Credits / Ophthalmology, Optometry

Leveraging Novel Therapies to Transform Demodex Blepharitis Care

May 13, 2025 | 7:00 PM ET

Patient-Centered Treatment Plans for Management of Neovascular (Wet) AMD and Diabetic Macular Edema: Insights on Recent Efficacy, Safety, and Real-World Data to Improve Adherence and Outcomes

1.5 Credits / Ophthalmology/Optometry

Leveraging Novel Therapies to Transform Demodex Blepharitis Care (6/11)

Jun 11, 2025 1:00 PM ET

Integrating Multi-Cancer Early Detection Tests Into Clinical Practice: The Health Economics Perspective for Managed Care Professionals

1.5 Credits / Oncology

The Evolving Strategies for Managing nAMD and DME: Empowering Managed Care Decisions for Improved Patient Outcomes

1.5 Credits / Endocrinology, Diabetes & Metabolism, Ophthalmology/Optometry

More News

Scheimpflug Imaging Helps Predict Corneal Edema Resolution After DMEK

March 3rd 2021

Scheimpflug Imaging Helps Predict Corneal Edema Resolution After DMEK

Findings of post hoc analyses published in JAMA Ophthalmology suggest that preoperative Scheimpflug imaging can help predict corneal edema resolution following Descemet membrane endothelial keratoplasty (DMEK).

Study Supports Preschool-Based Vision Screening Programs to Increase Glasses Wear

March 1st 2021

Study Supports Preschool-Based Vision Screening Programs to Increase Glasses Wear

Research published in JAMA Ophthalmology supports the continued implementation of preschool-based vision screening programs, as nearly 3 of 4 preschool students consistently wore their glasses at school during the first year of use.

Survey: Thyroid Eye Disease Reduces Quality of Life Beyond Acute Phase

February 25th 2021

Survey: Thyroid Eye Disease Reduces Quality of Life Beyond Acute Phase

A new survey conducted by Horizon Therapeutics highlighted the negative impacts thyroid eye disease have on patients’ quality of life, finding effects often continue beyond the acute disease phase and into a chronic phase.

Investigation Finds Tuberculosis May Be Risk Factor for Behçet Disease

February 23rd 2021

Investigation Finds Tuberculosis May Be Risk Factor for Behçet Disease

An analysis of human genetic and biomarker data found that tuberculosis was a risk factor for Behçet disease, a noninfectious uveitis condition.

Eye Health

February 19th 2021

Central Retinal Artery Occlusion Rates in Korea Decreased Over Time, Study Finds

Rates of central retinal artery occlusion (CRAO), which is associated with and shares common risk factors with cardiovascular diseases, have decreased over time in Korea, a recent cohort study of 50 million residents found.

Umbrella Review Highlights Global Scope of Vision Impairment, Reduced Quality of Life

February 16th 2021

Umbrella Review Highlights Global Scope of Vision Impairment, Reduced Quality of Life

A global analysis of 9 systematic reviews found a consistent association between vision impairment, eye diseases, and reduced quality of life.

Researchers Identify Candidate Factors Associated With Visual Impairment in Diabetic Eyes

February 10th 2021

Researchers Identify Candidate Factors Associated With Visual Impairment in Diabetic Eyes

Using optical coherence tomography, researchers found that length of disorganization of retinal inner layer, length of external ellipsoid zone disruption, and foveal avascular zone circularity were associated with visual impairment in treatment-naïve patients with diabetes.

Retinal Measures Potential Biomarkers for Sickle Cell Disease Progression

February 8th 2021

Retinal Measures Potential Biomarkers for Sickle Cell Disease Progression

Results of a longitudinal prospective case-control study found rates of retinal thinning were higher among individuals with sickle cell retinopathy compared with individuals without the condition.

Air Pollution Associated With Increased Rates of AMD

February 3rd 2021

Air Pollution Associated With Increased Rates of AMD

Greater exposure to particulate matter2.5 was associated with an 8% increase in self-reported age-related macular degeneration (AMD).

Examining the Potential of CRISPR Base Editing for Inherited Retinal Diseases

February 2nd 2021

Examining the Potential of CRISPR Base Editing for Inherited Retinal Diseases

A substantial proportion of patients with inherited retinal disease could be treated with base editing, while therapeutic strategies that focus on common variants could be used to treat a large number of patients with the disease, according to study results.

Metformin Use Linked to Lower Odds of AMD Development

January 28th 2021

Metformin Use Linked to Lower Odds of AMD Development

Results of a case-control study show metformin use may protect against the development of age-related macular degeneration (AMD) in adults 55 years and older, and the association is dose-dependent, with the greatest benefit at low to moderate doses.

Close-up of irritated eye

January 25th 2021

Increased Hand Sanitizer Use Poses Risks to Children's Eyes

During the coronavirus disease 2019 pandemic in France, researchers found a 7-fold increase in the number of alcohol-based hand sanitizer eye exposures among children.

Study Finds Potential Biomarkers for Distinguishing Glaucoma Subtypes

January 19th 2021

Study Finds Potential Biomarkers for Distinguishing Glaucoma Subtypes

Results from a prospective observational study showed aqueous transforming growth factor beta and autotaxin exhibited high diagnostic performance in detecting glaucoma subtypes and could serve as promising biomarkers for glaucoma.

Gastric Bypass Surgery Associated With Lower Risk of Diabetic Retinopathy Development

January 18th 2021

Gastric Bypass Surgery Associated With Lower Risk of Diabetic Retinopathy Development

Swedish patients with type 2 diabetes and obesity who underwent gastric bypass surgery exhibited a reduced risk of developing new diabetic retinopathy, compared with those who did not undergo surgery.

How Does Home Confinement Impact Children’s Eyesight?

January 14th 2021

How Does Home Confinement Impact Children’s Eyesight?

Home confinement during the coronavirus disease 2019 pandemic was associated with a significant myopic shift among Chinese children aged 6 to 8, according to new research published in JAMA Ophthalmology.

Close-up of green eye

January 11th 2021

Study Evaluates Efficacy of At-Home Visual Acuity Test

Study results, published in JAMA Ophthalmology, showed the Home Acuity Test can be used to measure visual acuity by telephone for a wide range of outpatients with diverse conditions under the care of an ophthalmologist.

Deep Learning Model Detects Sea Fan Neovascularization in Patients With Sickle Cell Hemoglobinopathy

January 5th 2021

Deep Learning Model Detects Sea Fan Neovascularization in Patients With Sickle Cell Hemoglobinopathy

In an effort to detect sea fan neovascularization from ultra-widefield color fundus photographs from patients with sickle cell hemoglobinopathy, researchers developed an automated system with high sensitivity and specificity, which holds potential to improve screening for vision-threatening proliferative sickle cell retinopathy.

Decreased Retinal Vessel, Perfusion Densities Found in Those With Parkinson Disease

January 4th 2021

Decreased Retinal Vessel, Perfusion Densities Found in Those With Parkinson Disease

Results from a cross-sectional study show individuals with Parkinson disease exhibited decreased retinal vessel and perfusion density, as well as choroidal structural changes compared with age- and sex-matched controls.

Infant Cataract Surgery Increases Long-Term Glaucoma Risk, Regardless of IOL Implants

December 31st 2020

Infant Cataract Surgery Increases Long-Term Glaucoma Risk, Regardless of IOL Implants

Among children who underwent unilateral cataract removal in infancy, risk of glaucoma-related adverse events continues to increase with longer follow-up and is not associated with primary intraocular lens (IOL) implementation, according to research published in JAMA Ophthalmology.

Top 5 Most-Read Ophthalmology Stories of 2020

December 29th 2020

Top 5 Most-Read Ophthalmology Stories of 2020

In a year in which health care professionals were forced to alter treatment plans to adjust to an ongoing health crisis, the majority of our most popular ophthalmology stories of 2020 involved the intersection of ophthalmologic care and coronavirus disease 2019.

Study to Measure Patient-Reported Outcomes Before and After Minimally Invasive Glaucoma Surgery

December 24th 2020

Study to Measure Patient-Reported Outcomes Before and After Minimally Invasive Glaucoma Surgery

Verana Health, along with the FDA, the American Glaucoma Society, and American Academy of Ophthalmology, recently announced the launch of the Patient-Reported Outcomes for Minimally Invasive Glaucoma Surgery study with the first patient enrolled.

“Sore Eyes” Reported as Most Significant Ocular Symptom of COVID-19

December 21st 2020

“Sore Eyes” Reported as Most Significant Ocular Symptom of COVID-19

The most significant ocular symptom experienced by those suffering from coronavirus disease 2019 (COVID-19) was sore eyes, according to new research published in BMJ Open Ophthalmology.

Inner Retinal Thinning Associated With Hallucinations in Parkinson Disease

December 15th 2020

Inner Retinal Thinning Associated With Hallucinations in Parkinson Disease

Visual hallucinations (VH) among patients with Parkinson disease (PD) appear to be associated with thinning of the inner retina, according to research published in Scientific Reports.

What Leads to DMD During Cataract Surgery?

December 14th 2020

What Leads to DMD During Cataract Surgery?

Friction of surgical instruments has the greatest association with incisional Descemet membrane detachment (DMD) during cataract surgery, according to results of a case series published in JAMA Ophthalmology.

Pile of opioids and needle

December 10th 2020

State Legislation Associated With Lower Opioid Prescriptions for Oculoplastic, Orbital Procedures

During the enactment period of recent Michigan opioid laws, a reduction in opioid prescriptions for oculoplastic and orbital procedures was observed and appeared to be sustained, according to research published in JAMA Ophthalmology.

Study Links Increases in RRD, Myopia Incidence

December 8th 2020

Study Links Increases in RRD, Myopia Incidence

An increase in primary rhegmatogenous retinal detachment incidence (RRD) may be associated with a simultaneous increase in myopia among citizens residing in the Netherlands, according to study results published in JAMA Ophthalmology.

Brain imaging

December 3rd 2020

Understanding the Relationship Between BBBD Therapy and Maculopathy

Results of a retrospective case series revealed an association between blood-brain barrier disruption (BBBD)–related maculopathy and the number of BBBD treatment sessions patients underwent, suggesting a dose-dependent effect of the treatment.

Tool May Help Non-Ophthalmologists Triage Patients With Serious Ocular Injuries

December 1st 2020

Tool May Help Non-Ophthalmologists Triage Patients With Serious Ocular Injuries

By analyzing retrospective consecutive case series, researchers identified 5 clinical and radiographic variables associated with increased risk of serious ocular injury in patients with orbital fracture to aid non-ophthalmologists in triaging these patients for urgent ophthalmologic evaluation.

Detailed eye graphic

November 27th 2020

Diffuse Macular Damage Linked to Diminished Facial Recognition, Contrast Sensitivity

Among patients with glaucoma, diffuse rather than focal glaucomatous macular damage was associated with diminished facial recognition and contrast sensitivity, according to results of a cohort study published in JAMA Ophthalmology.

Visual Field Defects Are Consistent in Macular Measurements Among Those With Glaucoma, High Myopia

November 25th 2020

Visual Field Defects Are Consistent in Macular Measurements Among Those With Glaucoma, High Myopia

Findings published in BMC Ophthalmology suggest that during diagnosis and follow-up of glaucoma with high myopia, more attention ought to be focused on structure and functional defects in macular areas.

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