Ophthalmology

In a longitudinal cohort study, researchers identified 17 seemingly novel variants of the PDE6A retinitis pigmentosa gene, suggesting it may be amenable to gene therapy.

Anti–vascular endothelial growth factor (VEGF) treatment was associated with preserved useful visual acuity in almost 20% of patients with neovascular age-related macular degeneration (nAMD).

Although probing for congenital nasolacrimal duct obstruction is safe and effective , age at the time of initial intervention and bilateral surgery constitutes a significant risk for a failed procedure, according to study results published in BMC Ophthalmology.

Acute coronary syndrome (ACS) was associated with lower inner vessel length density, measured via optical coherence tomography angiography (OCT-A), and with higher concentrations of angiopoietin-2 and osteoprotegerin, according to study results published in Scientific Reports.

Compared with placebo, low-dose atropine (0.01%) eyedrops may slow myopia (nearsightedness) progression and axial elongation in Chinese children with low and moderate myopia.

Researchers found the nucleocapsid protein (NP) antigen of SARS-CoV-2, the virus which causes coronavirus disease 2019 (COVID-19), existed intracellularly in the ocular tissues of a patient who previously had COVID-19.

Oxymetazoline, 0.1% may hold potential as a promising treatment option for individuals with acquired blepharoptosis, according to results of a pooled analysis published in JAMA Ophthalmology.

In patients with idiopathic epiretinal membrane (ERM), membrane contraction contributed to increased choroidal thickness, according to study results published in PLoS One.

Federal policy in the United States and Canada prohibiting men who have sex with another man (MSM) from donating corneas has led to the disqualification of between 1558 and 3217 cornea donations in 2018 alone, according to research published in JAMA Ophthalmology.

For the first time, researchers demonstrated that quantitative pupillary light reflex (PLR) metrics can be used to differentiate concussed adolescent athletes from healthy athletes.

The risk of developing high myopia is relatively high among children with myopia onset at a young age, while each year of delay in the age of onset substantially reduces the chance of developing high myopia in adulthood.

Among individuals hospitalized with coronavirus disease 2019 (COVID-19) in Suizhou, China, the proportion of patients who wore glasses for extended daily periods was smaller than the general population.

In children, high add power multifocal contact lenses significantly reduced the rate of myopia (nearsightedness) progression over 3 years compared with medium add power and single-vision lenses.

In patients with central serous chorioretinopathy, eyes treated with intravitreal bevacizumab injections and which achieved complete resolution of subretinal fluid have a 50% chance of CSC recurrence in the long term.

Point-of-care diabetic retinopathy screening using autonomous artificial intelligence (AI) systems is effective and cost-saving for children with diabetes and their caregivers.

Survey results show the coronavirus disease 2019 pandemic will leave some pediatric ophthalmology practices strained if not irreparably harmed.

For the first time in the United States, researchers have rebuilt damaged corneas using a patient’s own stem cells to aid in the recovery from ocular injuries such as chemical burns.

Children hospitalized with coronavirus disease 2019 (COVID-19) in Wuhan, China presented with a series of eye manifestations, according to a new study.

Sex may play a modifying role in the 25% of patients with Stargardt disease who carried a combination of a mild and a severe allele, according to results of a cross-sectional study published in JAMA Ophthalmology.

According to a review published in Eye and Brain, the use of OCT-A, a noninvasive imaging technique for analyzing the retinal and choroidal microvasculature in vivo, can play a pivotal role in the detection and monitoring of neurodegenerative diseases.

A study published in JAMA Ophthalmology found that as of April 30, 2020, most practices were complying with American Academy of Ophthalmology (AAO) guidelines for scheduling patients during the pandemic.

Retinal venular widening and a higher vessel tortuosity are associated with lower performance of short-term visual recognition memory in children aged 4 to 5 years, according to a study published in JAMA Network Open.

Despite triage systems in place to exclude patients with coronavirus disease 2019 (COVID-19), viral material was found on ophthalmology examination room surfaces at one center, though the infectivity of the samples was unknown.

New study results published in JAMA Ophthalmology suggest researchers can leverage big data to triage ophthalmic clinic appointments, balancing the glaucoma progression risk against the morbidity risk from coronavirus disease 2019 (COVID-19) exposure during ophthalmic care.

Ranibizumab, in combination with prompt verteporfin photodynamic therapy, is more effective in treating polypoidal choroidal vasculopathy compared with ranibizumab monotherapy, according to a study published in JAMA Ophthalmology.