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Given the observed outcomes, camlipixant merits further study in severe RCC, especially among patients with a high initial cough burden. | Image credit: sebra - stock.adobe.com

A phase 2a trial of camlipixant, a selective P2X3 receptor antagonist, found that while the drug did not significantly reduce cough frequency in the overall population with refractory chronic cough, it produced meaningful improvements in patients with a higher baseline cough burden.

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