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Treatment with Symtuza (darunavir 800 mg/cobicistat 150 mg/emtricitabine 200 mg/tenofovir alafenamide 10 mg) results in and maintains high virologic suppression rates, according to study findings presented at the 2018 Infectious Disease Week conference held in San Francisco, California.

A recent paper sought to address the knowledge gap in the literature with respect to the effects of cardiovascular events and thromboembolic events on healthcare cost associated with patients with polycythemia vera receiving hydroxyurea.

The Reagan-Udall Foundation for the FDA, a little-known nonprofit set up by Congress over 10 years ago to help the agency work with the private sector, is still struggling with funding as well as questions about its mission; the preferences of millennials are changing the traditional model of office-based primary care; Democrats are planning to force a vote in the Senate this week on overturning a Trump administration rule expanding short-term health insurance plans.

Patient preference should be considered because medications don't work if adherence is poor, the experts noted.

Some patients with chronic obstructive pulmonary disease (COPD) experience a sudden worsening of their symptoms that require additional treatment—also known as acute exacerbation of COPD (AECOPD). A recent study, which investigated whether readmissions of patients with severe AECOPD varied according to the bacterium or virus identified, found that P. aeruginosa identification is associated with a higher readmission rate in patients.

A new study examining the effect of high-deductible health plans (HDHPs) on low-income adults with multiple chronic conditions found that almost half had a family out-of-pocket (OOP) healthcare burden exceeding 20% of family disposable income.

The decline in fractures caused by osteoporosis has stagnated, leading bone experts to suspect a lack in osteoporosis diagnosis and treatment guideline adherence. To combat this, the American Society for Bone and Mineral Research (ASBMR) has added 5 clinical care recommendations to prevent secondary fractures in at-risk patients.

Patients with acute myeloid leukemia (AML) and febrile neutropenia that are de-escalated on day 5 if they were afebrile, hemodynamically stable, and without evidence of infection, had similar clinical outcomes and a decreased incidence of Clostridium difficile infections compared with patients without these early on re-evaluations for de-escalation.

Insurers in the individual market have shown improved financial results for the first 6 months of 2018 to levels not seen since before the passage of the Affordable Care Act (ACA); women can experience lingering health problems years after workplace sexual harassment or sexual assault; people addicted to opioids are trying to self-treat withdrawal by using buprenorphine, 1 of 3 federally approved medications to treat opioid use disorder.

The dual inhibitor first blocks 2 kinases that are known to aid the growth of malignant B cells, and then it disrupts the microenvironment that supports tumor growth.

Opioid abuse-deterrent formulations (ADFs) represent 1 aspect of an opioid risk management plan that is aimed at managing a patient’s pain relief and quality of life while also protecting against harmful outcomes of opioid misuse. A report, published by the Journal of Multidisciplinary Healthcare, outlined ADF types and strategies and concluded all stakeholders play a role and must cooperate with opioid risk management in order to be effective.

In a study presented at the American Society of Clinical Oncology Quality Care Symposium last month, researchers looked to assess the adherence to National Comprehensive Cancer Network (NCCN) guidelines in the neoadjuvant treatment of breast cancer and the impact on outcomes.

A recent retrospective analysis examined changes in diagnosis after a second opinion for patients with breast cancer from a multi-disciplinary tumor board review at a National Cancer Institute-designated cancer center.

Here are 5 things to know about antimicrobial resistance (AMR), one of the most urgent threats to public health.

An audit feedback intervention is an approach used to help providers translate evidence into behavior change, and at ID Week, 1 abstract showed that it helped reduce antibiotic prescribing for acute respiratory infections (ARIs). Another report showed that antibiotic prescribing rates for ARIs at medical centers operated by the Department of Veterans Affairs (VA) have steadily declined since 2010. ID Week is an annual conference focused on many different infectious disease topics.

Two studies presented at the American Society for Bone and Mineral Research 2018 Annual Meeting last month specifically addressed men’s bone health and compared their risks with those of women.

Previous phase 3 studies have demonstrated the efficacy of nebulized glycopyrrolate inhalation solution (GLY) for treating patients with chronic obstructive pulmonary disease (COPD). In a recent study, researchers conducted a secondary analysis and found that nebulized GLY demonstrated efficacy and was well tolerated for up to 48 weeks in subjects with COPD with or without background long-acting beta2-agonist (LABA).

A study found a lack of consistent and comprehensive coverage throughout the country, identified coverage-related challenges to accessing asthma care within states, and found substantial gaps between guidelines-based asthma care and coverage by state Medicaid programs.

Health plans sold through Iowa’s Farm Bureau will ask applicants if they have any pre-existing conditions, and some applicants could be denied coverage based on their answers; Congress this week approved rare bipartisan legislation aimed at curbing opioid use disorder, giving lawmakers something to campaign on ahead of the November midterms; a new study sought to assess the cost to produce insulin and to examine how biosimilar insulin, if manufactured on a large scale, could reduce the cost of treatment for patients with diabetes.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

The type of cancer a provider treats can determine how well he or she performs under the Oncology Care Model (OCM), according to research from Avalere Health that was presented at the American Society of Clinical Oncology Quality Care Symposium.

This week, the top managed care news included the Nobel Prize in Medicine was awarded to 2 people for research into immunotherapy; physician-run accountable care organizations bring savings for Medicare; research highlights the health impacts of sexual harassment and assault.

The ornithine decarboxylase 1 (ODC1) gene, for the first time in humans, has been linked to a new pediatric disorder leading to macrosomia, macrocephaly, developmental delays, alopecia, hypotonia, and hearing loss, according to a new report.

This week, infectious disease specialists from different organizations are meeting in San Francisco for ID Week, an annual conference focused on many different infectious disease topics and their intersection with cancer, HIV, respiratory diseases, and more. Two abstracts presented results about what is needed to prevent complications in cancer care, one about patients with acute myeloid leukemia (AML) with prolonged neutropenia, and one examining the frequency of antimicrobial complications following initiation of palliative chemotherapy.

Pharmacy benefit managers (PBMs) will have to disclose some information about their compensation and relationships with payers.

Researchers developed a set of items based on a previous literature review and patients’ focus groups and tested it on a wide set of patients with episodic and chronic migraine.

Although what is known about the impact of rising minimum wages on health is just beginning, the research that is available points to some important health benefits, according to a new policy brief in Health Affairs. And, a possible new source of data to mine could arise over the next few years, stemming from Amazon's announcement this week that it will raise its minimum wage to $15 an hour for its employees in the United States.

Cervical cancer could be eliminated in Australia within the next 2 decades because of a free government program to vaccinate children against the human papillomavirus; employers have slowed enrollment in high-deductible health plans amid a very tight labor market and a postponement of a tax on healthcare coverage; President Barack Obama’s 2010 healthcare law is threatening Republicans in the midterms who have spent years railing against it and seeking its repeal.