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With the approval, zilucoplan becomes the first once-daily subcutaneous complement C5 inhibitor available for adults with generalized myasthenia gravis.

Adding pembrolizumab to combination of trastuzumab and chemotherapy improved progression-free survival vs placebo plus trastuzumab and chemotherapy in the first-line treatment of patients with metastatic HER2-positive gastric or gastroesophageal junction (GEJ) cancer.

A study assessing an experimental cell-free DNA myelination liquid biopsy test was found to be 91% accurate at identifying early-stage epithelial ovarian cancer.

Both adolescents and adults saw improvements with the use of ruxolitinib or povorcitinib to treat their nonsegmental vitiligo.

New research found that people who routinely eat high amounts of red meat have a 62% higher risk of developing type 2 diabetes, supporting dietary recommendations to limit red meat consumption.

During a recent Institute for Value-Based Medicine® event, speakers discussed the use of immunotherapy and targeted therapy to treat melanoma and managing the toxicities of these treatments.

Of the 333 patients with psoriatic arthritis (PsA) and 457 patients with axial spondyloarthritis (axSpA), there were 1.09 serious infections per 100 patient-years.

A small portion of these patients with a high inhaled corticosteroid (ICS) dosage will continue use of a second medication to keep their asthma under control, according to study findings.

Including biomarkers for non-ADAMTS13 in routine clinical testing could benefit diagnosis and follow-up in patients with immune-mediated thrombotic thrombocytopenic purpura (TTP).

“There are things more important than our discomfort, and there are things that are more important than even our fear—inclusion is more important,” said Erica Marsh, MD, MSCI. “Our care of our patients and loved ones is more important, and our existence tomorrow has to be more important than our fears today.”

The authors discussed a polymorphism of the LEP gene associated not only with cancer, but also with chronic diseases including obesity and diabetes, offering them a reason to look into the relationship between LEP and myelodysplastic syndrome (MDS).

Three US senators asked the Social Security Administration to respond to a report saying it reduced or suspended benefits for those who received COVID-19 relief payments; mifepristone, a drug taken to help manage miscarriages, remains widely unavailable to patients experiencing pregnancy loss; pharmaceutical companies are beginning trials to get weight-loss shots approved for patients with obesity 6 years and older.

A panel held at Fall Clinical Dermatology 2023 emphasized the role of Janus kinase (JAK) inhibitors in several skin conditions and highlighted new therapies in the space.

A recent study suggests that more intensive triplet therapy is more effective than less intensive doublet therapy in frail patients with newly diagnosed multiple myeloma (MM), and that more intensive treatment may even improve frailty itself.

The FDA has approved the CRCdx RAS Mutation Detection Kit as a companion diagnostic for panitumumab in the treatment of patients with metastatic colorectal cancer (mCRC), according to an announcement from EntroGen.

Posters presented at the American Society for Reproductive Medicine 2023 Scientific Congress & Expo highlighted trends in fertility care amid the turbulent landscape following the Dobbs decision.

Results of the monarchE study showed patients with hormone receptor–positive (HR+), HER2-negative (HER2–) high-risk, early breast cancer had greater benefit after 5 years when receiving adjuvant abemaciclib plus endocrine therapy vs endocrine therapy alone.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Posters presented at the American Society for Reproductive Medicine (ASRM) 2023 Scientific Congress & Expo addressed psychosocial symptoms and burdens faced by both embryologists and women of color with uterine fibroids.

Researchers found that heated tobacco products can reduce risks of exacerbations and exposure to toxic chemicals compared with combustible cigarettes in patients with chronic obstructive pulmonary disease (COPD).

Study investigators note their meta-analysis may be the first to demonstrate the importance of interventions to support adherence to adjuvant endocrine therapy for breast cancer.

Valerie Montgomery Rice, MD, FACOG, a distinguished infertility specialist, highlights the pivotal role of cultural humility, diversity, acknowledgment of historical injustices, and collective action in addressing disparities and fostering equitable access to health care.

A 5-year randomized trial showed that the Million Hearts Model, which paid health care organizations to monitor and reduce cardiovascular disease (CVD) risk, was effective in reducing first-time heart attacks and strokes without associated increases in Medicare spending.

Operational forecasting for patients who are eligible for gene therapies will be crucial for addressing the accessibility and affordability challenges with these agents, especially as more gene therapies are expected to enter the market in the next few years.

Anita Allen, PhD, professor of law and philosophy, University of Pennsylvania, discusses the impact of abortion regulations in different parts of the world on women's reproductive access and rights, as well as the repercussions of the Dobbs decision that overturned Roe v Wade.

Eric Donnenfeld, MD, from Ophthalmic Consultants of Long Island, discusses the importance of the Xdemvy FDA approval in treating patients with Demodex blepharitis.

Monica Bertagnolli, MD, fielded questions on hot-button issues during the long-delayed Senate hearing on her nomination to head the National Institutes of Health; Pfizer announces the list price for a 5-day course of its COVID-19 antiviral, nirmatrelvir/ritonavir (Paxlovid); a federal initiative is distributing funds to programs aiming to prevent drug overdoses in pregnant women.

Individuals aged up to 24 years living with HIV were likely to be satisfied with and would recommend telehealth services to their friends, a recent study found.