All News

The review of 5 phase 3 randomized controlled trials found that overall, the combination treatments improved survival outcomes while eliciting more, but manageable, side effects.

A narrative review found that some risk factors may be associated with cognitive impairment in patients with type 1 diabetes.

As the feasibility of phase 1 clinical trials for prenatal spinal muscular atrophy (SMA) therapies is explored, patient and parent input on prenatal testing and possibly treatment is a valuable tool for guiding research discussions.

Nurse-led education is an essential aspect of care for patients with bleeding disorders, but there is currently a lack of research on specific strategies to improve patient self-management through education.

A new analysis found only 1 in 10 studies of inequities in liver cancer had a European focus or origin.

New studies have linked a diet of ultra-processed food to a higher risk of colorectal cancer and to an overall risk of mortality; the CDC endorsed the updated booster shots from Moderna and Pfizer-BioNTech for use against the omicron variant; South Carolina Department of Corrections and Pear Therapeutics are teaming up to support inmates recovering from substance use disorders.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

While there are a number of treatment options available for patients with chronic obstructive pulmonary disease, not all options are right for all patients.

While there are a number of treatment options available for patients with chronic obstructive pulmonary disease, not all options are right for all patients.

A high-dose influenza vaccine reduces the risk of death and incidence of hospitalization for influenza and pneumonia among older adults.

This open-label extension of the SERAPHIN trial evaluated the long-term safety and tolerability of a small daily dose of the endothelin receptor antagonist against pulmonary arterial hypertension (PAH) among patients from the original study.

Medication-at-home pharmacy is an innovative method of medication management that is vital to the success of the health care system.

A highly tailored video doctor intervention was shown to help men living with HIV achieve viral suppression, and younger and older patients achieve HIV care retention.

Understanding if local prescription patterns are influenced by guidance could help policymakers understand what is needed to further encourage a shift to asthma inhalers with less of a climate impact.

People with type 1 diabetes (T1D) who partake in fasting during Ramadan may benefit from using an advanced hybrid closed loop (AHCL) insulin pump system.

Olipudase alfa (Xenpozyme) was granted FDA approval for patients with Acid Sphingomyelinase Deficiency (ASMD); Moderna and Pfizer-BioNTech’s bivalent COVID-19 vaccines are each authorized for use as a booster dose; people with type A blood have an 18% higher risk of stroke before age 60, compared with other blood types.

Post hoc analyses of the phase 3 PEGASUS trial found that clinical and hematological improvements were associated with better patient-reported fatigue and physical function outcomes in paroxysmal nocturnal hemoglobinuria, for an overall bettering of health-related quality of life (HRQOL).

A randomized, controlled, experimental study found that a breathing exercise decreased fatigue and daytime sleepiness at the end of the fourth and eighth weeks of an intervention in patients with obstructive sleep apnea (OSA).

In this new study, investigators searched for potential predictors of melanoma thickness, with implications for treatment decisions regarding biopsy and excision margins.

A population-based cohort study of Hispanic Americans found that people who walked more per day had a lower risk of being diagnosed with type 2 diabetes.

US life expectancy fell by nearly a year in 2021 to 76.1 years; Pfizer’s COVID-19 pill reduced the number of hospitalizations and deaths among older adults during the Omicron surge in Israel; current smokers were found to have thicker, heavier, and weaker hearts compared with nonsmokers.

The researchers noted these improvements were seen without an increase in hyperlactatemia risk.

The findings mean it may be feasible to use adult systemic lupus nephritis (SLE) trial data to reduce the data needed for pediatric indications.

With evidence lacking on the role of inflammation in nasal polyposis (NP), this study investigated the role of 2 potential biomarkers in the nasal secretions of patients who have NP concomitant with aspirin-exacerbated respiratory disease.

People with advanced HIV initiating bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) were more likely to reach CD4 cell count levels of 200 cells/mcL or higher compared with those initiating other antiretroviral therapy (ART) regimens.

Sarah Wells Kocsis, MBA, is co-author of the Milken Institute report, “Chronic Kidney Disease: Finding a Path to Prevention, Earlier Detection, and Management.” She spoke to The American Journal of Managed Care® about the findings of the report and how they can be incorporated into care for patients with chronic kidney disease (CKD).

A cohort study found that there was an inverse association between COVID-19 infection and wearing glasses in an unadjusted analysis, although this association was not identified when adjusting for confounders.

House members in South Carolina will debate a total ban on abortions with no exceptions for rape or incest; the World Health Organization claimed that the monkeypox outbreak could be eliminated in Europe, citing slowing case counts; a study found that drinking black tea was associated with lower mortality risk.