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For pediatric patients with T-cell origin lymphoblastic leukemia (T-LBL) with disease progression following second-line treatment, investigators found that the JAK1/2 pathway may be a new actionable target through treatment with ruxolitinib.

Findings of the PANORAMA randomized clinical trial show that when patients with severe nonproliferative diabetic retinopathy were treated with intravitreal aflibercept, severity improved over 100 weeks and the likelihood of vision-threatening complications significantly reduced.

An overview of the latest news in Parkinson disease (PD) reported across MJH Life Sciences™.

Sifting through large quantities of data using artificial intelligence (AI) could one day change how nonalcoholic fatty liver disease (NAFLD) is diagnosed, managed, and treated, according to a recent review.

Use of electronic nicotine products was associated with an increased likelihood of dry nighttime cough and wheezing in adolescents, according to findings gleaned from a large survey.

Comorbid cardiac dysfunction and intrarenal venous congestion were shown in this new study to have a negative correlation with survival outcomes among individuals with all levels of heart failure.

A new study offers insight into ways to decrease the burden on caregivers for patients with chronic obstructive pulmonary disease (COPD) in China and around the world.

Medical experts express concern over the Biden administration's plan to administer boosters to the general public; US sees increases in vaccination rates and COVID-19 deaths; the CEO of Johnson & Johnson (J&J) will step down in January 2022.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

A review of therapies for atopic dermatitis (AD) found adequate net health benefit for new treatments. However, safety remains a concern for the Janus kinase (JAK) inhibitors.

A new mathematical model highlights the challenges of preventing Clostridioides difficile transmission in the hospital.

A study suggests that for patients with chronic kidney disease (CKD), the more components of metabolic syndrome present, the higher that patient’s risk of adverse cardiovascular outcomes.

The FDA has approved empagliflozin (Jardiance) for adults with heart failure with reduced ejection fraction, regardless of type 2 diabetes status.

A low risk of adverse safety outcomes was observed in anti–vascular endothelial growth factor (VEGF) intravitreal injections performed in office-based and operating room settings, with a higher rate of culture-positive endophthalmitis found in the office setting.

Study results point to a potential link between immunoglobin G (IgG) antibodies and migraine frequency, severity, and comorbidities.

Switching patients from reference pegfilgrastim to a biosimilar could lead to substantial cost savings, with potential to offset the cost of and allow for greater access to chemotherapy treatment, investigators concluded.

President Joe Biden pushes back against governors banning school mask mandates; family behind Purdue Pharma refuses to pay settlement for opioid suit without legal protections; the Environmental Protection Agency (EPA) bans a pesticide linked to health issues in children.

Actinic keratosis outcomes can be affected by several variables, and these lesions need to be treated to minimize progression risk, noted Todd Schlesinger, MD, FAAD, director, Dermatology and Laser Center of Charleston and Clinical Research Center of the Carolinas.

Few cases have documented how myeloproliferative neoplasms, such as polycythemia vera, progress to pure erythroid leukemia, with just 5 such cases reported between 1952 and 1962.

Investigators examined the current bodies of evidence surrounding the emergence of next-generation gene sequencing, and the challenges that come with it, for identifying oncogenic drivers of early-stage non–small cell lung cancer (NSCLC).

JDRF, the world's largest nonprofit funder of type 1 diabetes research, announced the appointment of Shereef Elnahal, MD, to its research committee.

Physical activity was significantly associated with cardiorespiratory fitness and pulse wave velocity, a preclinical indicator of future cardiovascular disease risk, in patients with psoriasis.

Top US health officials outlined plans for rolling out COVID-19 booster shots to all American adults beginning in September, while CMS announced that nursing homes will be required to implement mandatory vaccinations for staff.

"No matter where you go, there you are." Buckaroo Banzai

Some hospitals may revisit crisis standards of care; Florida hospitals to pause elective surgeries; studies find nearly a quarter of Black Americans with low incomes report fair or poor health care.

Event-free survival rates were higher in women compared with men for all-cause mortality and first heart failure hospitalization.

Asociaţia Română Anti-SIDA (ARAS; Romanian Association Against AIDS) was founded on April 10, 1992, just 3 years after the fall of communism, making it the first such organization in the country following a time when HIV was not officially acknowledged nor prevention of HIV and sexually transmitted infections discussed.

The scientific statement addresses current knowledge regarding the impact of obstructive sleep apnea on the cardiovascular health of children and adolescents, as well as best practices to evaluate symptoms.