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The studies used population-level data from a county in Minnesota that has served as a national laboratory for health research since the 1960s.

Robert Iannone, MD, MSCE, executive vice president of research and development for Jazz Pharmaceuticals, addresses findings of an abstract presented at ASCO 2021 which showed preliminary efficacy of lurbinectedin in combination with irinotecan in patients with advanced endometrial carcinoma.

Researchers discussed novel biomarkers—both established and not fully validated—being assessed in the time of targeted therapies for chronic lymphocytic leukemia (CLL).

Physical frailty affects a large proportion of patients with chronic obstructive pulmonary disease (COPD) and chronic respiratory failure and current tools for detection may be inadequate, according to a recent report.

The FDA said it is the first approved drug for chronic weight management in adults with general obesity or overweight since 2014.

Patients with glaucoma who were tested under a quantum dot LED were able to better distinguish differences in color, indicating that the quality of light systems may have an impact on color discrimination.

Davey Daniel, MD, hematology/medical oncology specialist, Tennessee Oncology, discusses findings of an abstract presented at ASCO 2021 showing a lower total cost of care paid by Medicare for episodes of care for patients in the Oncology Care Model (OCM) enrolled in clinical trials vs those receiving routine care.

ASCO officials characterized the results as practice changing and said they highlighted the need for genetic testing in patients who receive a diagnosis of high-risk breast cancer.

Results of a study conducted in California suggest some adolescents with type 1 diabetes (T1D) improved their glycemic control during the COVID-19 lockdown.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

This week marks the 40th anniversary of the CDC's June 5, 1981, Morbidity and Mortality Weekly Report describing rare instances of immunocompromised status among 5 homosexual men in Los Angeles. The American Journal of Managed Care® spoke recently with lead author Michael Gottlieb, MD, who was the first to describe what would come to be known as HIV and AIDS.

Stakeholders discuss barriers and solutions to employer engagement on value assessment, which includes redefining goals to that of the employer and patient, and moving beyond the scope of cost and clinical outcomes.

Various clinical trials are assessing the potential of neoantigen-based cancer vaccines.

Existing research has focused on skin symptoms, but a new study looks for alterations in the blood associated with moderate-to-severe atopic dermatitis.

Treating cough can be difficult. There are no FDA-approved therapies on the market in the United States, and companies with drugs in clinical trials have to contend with a large placebo effect.

The study of 57 patients with acute graft-versus-host disease (aGVHD) also showed that patients tolerated the treatment, offering promise for preventing and managing the complication of transplantation, which affects up to half of patients.

If 2020 was dominated by the news of how COVID-19 spread across the globe, then 2021 has so far been focused on ending the pandemic through vaccine distribution.

The new study identified altered microRNA (miRNA) in gray matter lesions, which could provide a new important marker of multiple sclerosis (MS) progression.

President Joe Biden announces a new initiative to get more adults vaccinated against COVID-19; Purdue Pharma may be immune from future opioid-related lawsuits; the California senate approves a bill decriminalizing psychedelic drugs.

This year's SLEEP 2021 virtual conference offers a wide range of sessions on topics relating to sleep disorder treatment and management.

Celltrion Healthcare’s high-concentration adalimumab biosimilar demonstrated comparable safety, efficacy, and immunogenicity profiles to the reference product for up to a year, providing further evidence supporting use of the product.

People who live in areas that have higher exposure to nitrogen dioxide were found to be at greater risk of Parkinson disease.

About 5.4% of patients with end-stage renal disease (ESRD) who begin renal replacement therapy as children go on to have vascular events, and 4.1% of those patients die as a result of vascular events, though the real incidence rates are likely higher, according to new research.

Findings from an observational study indicate that chronic migraineurs with medication overuse headache may be deficient in vitamin D.

Data from the DAPA-HF trial and published literature show intermediate-level cost-effectiveness of dapagliflozin use among patients with heart failure with reduced ejection fraction (HFrEF).

Data from a longitudinal study reveal poor glycemic control and blood pressure management may contribute to cognitive decline in older patients with type 1 diabetes.

On the eve of the 40th anniversary of the CDC’s first report on what would become known as HIV/AIDS, Perry N. Halkitis, PhD, MS, MPH, sends out an urgent call to continue this fight and rededicate resources to finding a cure.

The FDA releases label changes for ozanimod to treat multiple sclerosis; the National Institute of Allergy and Infectious Diseases initiated a study on mixing COVID-19 vaccines; gender-affirming hormones may affect the cardiovascular system.