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Classical mantle cell lymphoma (MCL) and 2 aggressive variants exhibited similar rates of negativity for the CD5 marker, but further testing may be needed in certain cases to avoid misdiagnosis with diffuse large B-cell lymphoma (DLBCL).

In patients with chronic inflammatory rheumatic and musculoskeletal diseases (RMD), the presence of metabolic syndrome (MetS) indicates an increased risk of cancer.

Study findings indicate that droplet digital polymerase chain reaction (ddPCR) may be more accurate than real-time quantitative PCR in measuring minimal residual disease (MRD) among pediatric patients with acute lymphoblastic leukemia (ALL), particularly in late follow-up time points.

Anemia, which occurs in over 50% of patients with end-stage kidney disease, should not be considered an obstacle to home dialysis, according to a new report.

Russell Langan, MD, chief of Surgical Oncology and Hepatopancreatobiliary Surgery at Saint Barnabas Medical Center, details the implementation of the center's Pancreatic Cyst Surveillance Program.

A quality assessment program conducted in the Republic of Korea may be effective in improving disease management and prognosis for patients with chronic obstructive pulmonary disease (COPD), but the effects may be temporary.

According to a recent review, data suggest mast cells have an important role in tissue homeostasis and wound healing, with mass cell dysregulation potentially leading to fibrotic disease.

As more therapies continue to be approved, efforts will focus on toxicity prevention and mitigation strategies for associated unique and potentially life-threatening adverse reactions.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Phase 3 data show the Pfizer/BioNTech vaccine is effective at preventing COVID-19 6 months after the second dose; the USDA will not move forward with a plan to cut food stamps; data reveal spike in drug overdose deaths during pandemic.

This week, the top news in managed care included COVID-19 cases surging as vaccine eligibility expands nationwide; Senate bill seeks to limit use of step therapy in employer health plans; a look into local and global awareness of the ongoing HIV/AIDS epidemic.

This video excerpt is our second entry in a 6-part series on individuals and international organizations working to bring local and global awareness to the ongoing HIV/AIDS epidemic, which is marking its 40th anniversary this year.

Idiopathic pulmonary arterial hypertension (PAH) is associated with iron deficiency, which is in turn associated with worse functional capacity and survival in PAH; however, iron repletion by infusion provided no significant clinical benefit.

A survey of employer and purchaser members of the National Alliance of Healthcare Purchaser Coalitions found that over half expect a transition to a more stabilized business environment by the third quarter of this year, as well as increased benefit offerings on mental health access and virtual care delivery.

Authors of a review article explore the role of HLA antigens in type 1 diabetes and autoimmune thyroid disease.

Kathy Oubre, MS, chief operating officer, Pontchartrain Cancer Center, explores US adoption of biosimilars ahead of her panel discussion at the 2021 Community Oncology Conference, as well as what sessions she’s looking forward to attending.

Researchers used deidentified real-world data to assess characteristics of patients who have received erenumab since its approval.

To mark the beginning of National Minority Health Month, The American Journal of Managed Care® (AJMC®) takes a look at racial inequities in the COVID-19 vaccine rollout and speaks with one expert who fears reality is worse than data indicate.

Women who received a type 1 diabetes (T1D) diagnosis prior to menstruation onset exhibited shorter reproductive periods compared with healthy controls.

Millions of Johnson & Johnson vaccines spoiled at a Baltimore production plant; CDC adds type 1 diabetes as a comorbidity increasing risk of severe COVID-19; study finds high rates of organ failure among patients with COVID-19 discharged from hospitals.

A review found that a low-carbohydrate diet may lead patients with type 2 diabetes to experience disease remission, potentially providing new insight into how clinicians can help patients better manage their disease, investigators concluded.

Disease severity was strongly associated with health-related quality of life, moderately associated with use of disability insurance, and weakly associated with household income for patients with sickle cell disease.

Among patients with multiple sclerosis, there is a 16% greater risk of infection, including for lower respiratory and herpes virus infections, after administration of fingolimod.

The number of days with sleep disturbance issues, such as difficulty falling and staying asleep, were greater in 2020 than in 2018, as was prevalence of both shorter and longer-than-recommended sleep durations during the pandemic.

Exercise may reduce vulnerability to cognitive decline among at-risk patients with Parkinson disease who have the gene variant APOE ε4.

A survey in France found that systemic medications are used by only half of dermatologists in treating atopic dermatitis, with methotrexate used more than cyclosporine.

Researchers found that physicians may have a financial conflict of interest when examining a chest x-ray for black lung disease, suggesting that sweeping changes are needed to avoid biases and improve transparency.

Using a support vector machine model, researchers were able to distinguish between eyes with pathologic myopia and healthy myopia.