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Treatment optimization for heart failure with reduced ejection fraction is the focus of the American College of Cardiology’s 2021 update to its 2017 Expert Consensus Decision Pathway on managing patients with the condition.

Patients with symptomatic acute hepatic porphyria were found to be at greater risk of accessing long-term sick leave and disability pension compared with the general population, but were not shown to be at an increased overall risk of premature death.

The Biden administration will reopen the health exchanges created by the Affordable Care Act (ACA); direct HHS and other agencies to reexamine other health policies, including Medicaid work requirements; and reverse the so-called global gag rule while affirming support for reproductive health.

Results of a case-control study show metformin use may protect against the development of age-related macular degeneration (AMD) in adults 55 years and older, and the association is dose-dependent, with the greatest benefit at low to moderate doses.

Rates of coronavirus disease 2019 (COVID-19) cases decline in 41 states; Aetna to cover medically necessary breast augmentations for transgender individuals; Oklahoma seeks to return $2 million worth of hydroxychloroquine.

Secukinumab rarely leads to latent tuberculosis infection as a reported adverse event and is supported for use in treating chronic systemic inflammatory conditions.

Physicians can withdraw inhaled corticosteroids (ICS) from triplet therapy without increasing patients’ risk of chronic obstructive pulmonary disease (COPD)-related exacerbations.

A 13.9% increase in diagnosed cases of HIV was seen following expansion of Medicaid coverage under the Affordable Care Act.

While these therapies continue to revolutionize the treatment landscape of SMA, treatments are not without shortcomings or challenges.

Telemedicine sprang up very quickly and will stay around to some extent once the pandemic ends, said Peter McAllister, MD, a neurologist, board certified headache specialist, and medical director of the New England Institute for Neurology and Headache.

The Biden administration promises to increase vaccine delivery; the FDA issues an alert on alcohol-based hand sanitizers from Mexico; 3 pharma giants partner to speed EU vaccination efforts.

Higher mortality rates were seen among patients with acute lymphoblastic leukemia (ALL) who were considered obese, in a recent study of patients treated at Mayo Clinic.

Treatment with erenumab led to improvements in pain, medication use, and quality of life in onabotulinumtoxinA-resistant patients with chronic migraine, according to study results published in The Journal of Headache and Pain.

Changes in blood pressure, percentage of red blood cells, and serum cholesterol levels were found to occur in patients with Parkinson disease before the onset of motor symptoms, suggesting potential biomarkers for early diagnosis and treatment.

Periodic review of treatment safety and monitoring are necessary as medical centers increasingly use newer disease-modifying therapies earlier in the course of multiple sclerosis.

Women receiving treatment for early-stage breast cancer may have a lower risk of developing heart failure if their therapy regimens include statins.

President Joe Biden reportedly will take executive action to reopen federal marketplaces selling Affordable Care Act (ACA) health plans; Moderna investigating booster shot designed to be more effective against emerging variants of coronavirus disease 2019 (COVID-19); Brazil coronavirus variant is found in Minnesota.

Several factors will have a significant impact in the health care industry in 2021, such as management of disparities in vaccine administration and greater investment in telehealth, said Gurpreet Singh, MBA, US Health Services Leader at PwC.

Metabolic surgery is more effective than conventional medical therapy in the long-term control of type 2 diabetes (T2D), according to results of a 10-year follow-up study of a randomized controlled trial published in The Lancet.

Daratumumab represents an important addition to the armamentarium of care for improving patient outcomes, said Mark Wildgust, PhD, vice president of Global Medical Affairs/Oncology at Janssen.

Patients with narcolepsy type 1 who are working or studying from home amid the coronavirus disease 2019 pandemic exhibited an increase in nocturnal sleep time and reduced daytime sleepiness. These patients also presented with significant weight gain.

During the coronavirus disease 2019 pandemic in France, researchers found a 7-fold increase in the number of alcohol-based hand sanitizer eye exposures among children.

President to sign travel ban meant to contain more contagious variants of coronavirus disease 2019 (COVID-19); limited vaccine supply concerns top health officials; Merck ends COVID-19 vaccine development.

Documented issues include lipid metabolic abnormalities, glucose metabolic abnormalities, and altered vitamin levels.

A recent study found that women had varying levels of willingness to use long-acting injectable HIV medications, based on their history with intravenous drug use.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

Pharmacy-led telehealth strategies will position Special Needs Plans (SNPs) for Star Ratings success during the pandemic and for years to come.

In a review published in Therapeutics and Clinical Risk Management, researchers outlined the current understanding of the transthyretin amyloidosis (ATTR) disease process, diagnostic and surveillance approaches, treatment modalities, and potential future directions.