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An abnormal red reflex finding most likely reflects an underlying ocular pathology in infants, but finding a normal red reflex during screening does not altogether exclude ocular disease.

Nearly 20 million people could be vaccinated against coronavirus disease 2019 in December; FDA approves a companion diagnostic for triple-negative breast cancer (TNBC); Anthony Fauci, MD, urges continued mask wearing as vaccines become available.

Although half of US rheumatologists have patients for which nonmedical switching has been suggested, only 35% were likely to switch patients with rheumatoid arthritis doing well on a reference product to a biosimilar.

Even heterosexual women are at risk of contracting HIV, so gay men should not be singled out as the only population with a transmission risk, said Milena Murray, PharmD, MSc, BCIDP, AAHIVP, associate professor, Midwestern University College of Pharmacy.

The investigator of the STRENGTH study says findings raise questions about the landmark REDUCE-IT trial, but other evidence suggests the drugs involved are different.

A loosening of Missouri’s permit-to-purchase and concealed carry firearm laws may have contributed to increased rates of firearm suicides among young residents, according to a recent study published in JAMA Network Open.

As some private health insurance companies move to end waivers of cost sharing for virtual care, there will be several aspects to monitor for employers, particularly its impact on accessibility and potential deferral of health care services.

Dupilumab, with or without topical corticosteroids, significantly reduced pain and discomfort in patients with moderate to severe atopic dermatitis.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

A study looking at chronic obstructive pulmonary disease (COPD) and coronary heart disease found that inhaled corticosteroids (ICS) reduced future cardiac events in patients not known to have coronary heart disease.

Lowering the higher rates of diabetes seen among racial and ethnic minorities requires solutions to address all of the major factors that contribute to diabetes prevalence.

A multidisciplinary spine intervention can reduce chronic back pain–related health care utilization and costs, according to a study published in Spine.

A registry study suggests 4 in 5 patients with heart failure might benefit from the SGLT2 inhibitor dapagliflozin.

Patients with Parkinson disease (PD) who do not experience tremor were found to show improvements in reward learning after taking dopaminergic medication, while those with PD and tremor exhibited no benefit in reinforcement learning.

Findings from the GALACTIC-HF trial presented at AHA Scientific Sessions 2020 showed that patients with heart failure (HF) with reduced ejection fraction who took omecamtiv mecarbil showed a significant 8% relative risk reduction in a composite of a HF event or death from cardiovascular causes, compared with those taking placebo.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

A look into the US cities hardest hit by cases of coronavirus disease 2019 (COVID-19); Anthony Fauci, MD, urges Americans to double down on health precautions amid COVID-19 surges; a study spotlights risk of high health care costs among the insured.

This week, the top managed care news included the Supreme Court signaling willingness to uphold the Affordable Care Act; Pfizer’s coronavirus disease 2019 vaccine shows 90% efficacy; racial disparities in lung cancer screenings and prescribing biologics.

Age, sex, and body mass index typically drive the development of obstructive sleep apnea, noted Krishna M. Sundar, MD, clinical professor, Pulmonary Division, Department of Medicine, medical director, Sleep-Wake Center, University of Utah.

Chimeric antigen receptor (CAR) T cells can be highly effective, but the durability of the therapy has been lacking in many patients with hematological malignancies. Many efforts are underway to fix this problem.

The FIDELIO-DKD program is perhaps just the beginning of seeing how finerenone can be used, said Rajiv Agarwal, MD, MS, FASN, a professor of medicine at Indiana University School of Medicine and a staff physician at the Veterans Affairs Medical Center in Indianapolis, Indiana.

Living in a neighborhood rife with violent crime and prostitution was linked in this recent study to worse virologic control among pregnant woman living with HIV.

A report by PwC discusses the health care agenda of President-elect Joe Biden, particularly how his term will shape the future of the Affordable Care Act, value-based care, and drug prices.

Researchers have identified additional mutations in both SMN1 and other genes, some of which may be associated with the onset of spinal muscular atrophy (SMA).

The Gates Foundation will add another $70 million of funding for vaccines and treatments against coronavirus disease 2019 (COVID-19); nursing homes see rising COVID-19 cases; finding health coverage for workers laid off due to the pandemic.

New research suggests it’s not disruptive to give radiation therapy to patients who are awaiting CAR T-cell therapy for relapsed or refractory multiple myeloma.

Michael S. Fitts, assistant dean for user access and diversity at the University of Alabama at Birmingham, discusses misconceptions of Parkinson disease related to race and age, as well as advice for patients in their treatment journey.

Experts spotlighted sex- and gender-specific changes in normal sleep and sleep disturbance, as well as attributable risk factors, during a session at the CHEST 2020 annual meeting.