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Bacterial changes in the oral cavity from immunosuppression, not HIV itself, are more likely to blame for the greater incidence of oral caries in children 6 months to 6 years, reports a study from the Department of Oral Biology at the Rutgers University School of Dental Medicine.

Researchers found that cough reflex sensitivity is amplified during chronic obstructive pulmonary disease (COPD) exacerbation and reduces after recovery, while its persistence can help serve as a predictor for future exacerbations.

The American College of Cardiology updates guidance on prescribing SGLT2 inhibitors and GLP-1 receptor agonists to patients with type 2 diabetes and cardiovascular disease or CV risk.

Hinge Health announced the expansion of its clinical and technical musculoskeletal (MSK) capabilities to cover the full continuum of MSK care. The move will provide the most complete back and joint health solution to employers and health plans.

A study based on real-world data collected from the West German Headache Center at the University Hospital Essen, Germany, concluded erenumab appears to be a promising treatment option for patients with highly therapy-refractory migraine.

Results from a large population-based cohort study, published in Arthritis Care & Research, found individuals with rheumatoid arthritis (RA) had a lower rate of incident type 2 diabetes (T2D) compared with the general non-RA population and cohorts with with hypertension, osteoarthritis (OA), and psoriatic arthritis (PsA).

Several issues are affecting the uptake of telehealth services among older adults; phase 1 trials results from Australia demonstrate immune responses from a coronavirus disease 2019 (COVID-19) vaccine candidate; Purdue Pharma could be on the hook for an $18.1-billion fine from the Justice Department.

Among the changes announced this week include the expanded use of telehealth in Medicare, giving payment parity to hospital outpatient surgery centers, simplifying evaluation and management codes, and changing performance measures for accountable care organizations (ACOs).

The coronavirus disease 2019 (COVID-19) vaccines that are leading the pack are utilizing a new vaccine technology that has never been approved for human use by the FDA. As a result, there are a lot of unknowns.

Evidence may support a greater comorbidity burden among patients with heart failure with preserved ejection fraction (HFpEF) or reduced ejection fraction (HFrEF), although this finding was shown to be worse among women with HFpEF.

Life expectancy trends in the United States "paint a troubling portrait of life and death," according to a new study published in The Milibank Quarterly. State policies have played an important role in the stagnation and recent decline in life expectancy.

Cognitive behavioral therapy for insomnia delivered via telemedicine was found to be noninferior to in-person delivery in managing severity, with similar improvements in daytime functioning exhibited between the 2 methods, according to study findings.

A Health Affairs study found 49% of all rural low-income communities have no intensive care unit beds; New York loosened its restrictions granting hospitals and care facilities some legal immunity during the coronavirus disease 2019 (COVID-19) pandemic; all students in New Jersey will be required to wear masks in school.

Higher-income countries are seeing their rates of premenopausal breast cancer increase faster, whereas cases of postmenopausal breast cancer are increasing in number faster in lower-income studies.

The ruling reversed a lower court ruling regarding the drug discount program for hospitals that serve patients covered by Medicaid.

Overall, there are 145 registered and ongoing clinical trials for therapies targeting Parkinson disease, of which 28 are currently in phase 3, according to review findings.

Deborah Birx, MD, warned the United States has entered a new phase in the coronavirus disease 2019 (COVID-19) pandemic; the United States will send $2 billion in funding to GlaxoSmithKline and Sanofi to ramp up production of a COVID-19 vaccine; the pandemic highlights health illiteracy among Americans.

Chronic migraine (CM) may be associated with widespread disruption of normal white matter (WM) integrity in the brain, according to a study published in The Journal of Headache and Pain.

A new treatment option is approved for patients with a common form of non-Hodgkin lymphoma who cannot have an autologous stem cell transplant.

Deirdre Ruttle, chief marketing officer, InstaMed and head of Wholesale Payments Healthcare Marketing, J.P. Morgan, discusses streamlined payment options in a post COVID-19 world.

Patients with rheumatoid arthritis (RA) have a higher risk of cardiovascular disease (CVD), because inflammation plays a pivotal role in the development of CVD. However, there is a need for greater improvement of CVD risk prevention.

A new study finds even if renal function is restored, patients who have severe renal impairment when diagnosed with multiple myeloma have lower overall survival rates.

Previous research has established acute graft-versus-host disease (GVHD) in the gastrointestinal tract as the primary cause of both GVHD severity and mortality, and as a result, emphasis is placed on preventing acute gut GVHD while still preserving the graft-versus-leukemia effect of allogeneic hematopoietic stem cell transplantation.

A shorter course of pulmonary rehabilitation, with phone support, improved symptoms and reduced hospital readmissions for patients with post-acute exacerbation in chronic obstructive pulmonary disease (AECOPD).

A study analyzing data from 2 Philadelphia hospitals shows pregnant black and Hispanic women are nearly 5 times more likely to be exposed to coronavirus disease 2019 (COVID-19); global reports of seasonal influenza are at record lows; economic disparities are highlighted by turnaround times for COVID-19 tests. 

This week, the top managed care news included top pharmaceutical executives refuse to attend a Trump meeting after executive orders on costs; a survey shows concerns about reopening schools, toll of COVID-19 split by party lines, background; a review of 20 years of data concludes vaccines are "remarkably safe."

The ADAURA trial was stopped in April 2020 after an independent monitoring committee called for the trial to be unblinded 2 years early based on a determination of overwhelming efficacy.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.