Clinical

The presence of sex differences in immunological functioning influences hidradenitis suppurativa (HS).

Researchers suggest providers learning more about e-cigarettes and updated, effective cessation methods could help their patients overcome barriers to smoking cessation treatment.

Findings from a retrospective analysis suggest an association between bridging therapy and poorer outcomes among patients with aggressive, relapsed/refractory B-cell non-Hodgkin lymphoma (NHL).

Researchers found that costs were highest for those with hospital-onset clostridioides difficile infection (CDI), lower for those with community onset-health care facility association CDI, and lowest for those with community-associated CDI.

Studies showed the various treatments improved symptoms, but more trials need to be done.

Patients given LNK01001 showed significant improvement in Eczema Area and Severity Index scores over placebo.

New research found that ovarian cancer risk is reduced by salpingectomy just as much as by tubal ligation, contradicting guidelines that suggest otherwise.

Researchers found that 2.4% of the adult UK population had active atopic dermatitis (AD) between 2015 and 2019, the majority of which were mild cases of AD, as only 7.5% to 8.3% of the population had moderate to severe AD.

Dr Carney opens a discussion around factors impacting schizophrenia in patients.

Sandy Dimiterchik, an advocate for patients diagnosed with schizophrenia, leads the panel in a discussion highlighting barriers that inhibit optimal patient care.

The study was designed to help scientists better understand how to prevent in-hospital transmission of Clostridioides difficile.

Anthracyclines are widely used to treat hematological and solid-tumor cancers, but past research suggests their use may be associated with late cardiac effects, including heart failure, among patients with lymphomas and other cancers.

Patients with Prader-Willi syndrome showed early signs of microvascular disease upon screening.

Study authors used data from the Taiwan National Healthcare Insurance Research database and Death Registry for their population-based retrospective cohort study.

Investigators from China used circulating tumor DNA testing alongside bone marrow assessments to evaluate patients' pretreatment and posttreatment disease levels and to track the course of the disease.

Survey responses revealed the rates and times at which patients switched from oral to biologic therapies.

Although B-cell lymphomas can be challenging to study, there have been great advances in treatments in the second-line and later, explained Kami Maddocks, MD, professor of Clinical Internal Medicine, the Ohio State James Comprehensive Cancer Center.

The researchers conducted this study as previous ones have not assessed death rate variations among patients with chronic obstructive pulmonary disease (COPD) across the urban-rural gradient.

A global assessment found that there was a high prevalence of chronic pain in women living with HIV.

Maia Kayal, MD, MS, and Kimberly C. Chen, DO, MSHLM, discuss challenges for biosimilars with interchangeable designation related to automatic substitution in the pharmacy.

Kimberly C. Chen, DO, MSHLM, discusses the potential benefits of interchangeable biosimilars to patients and payers.

The phase 3 ENHANCE trial evaluating the first-line combination of magrolimab and azacitidine vs placebo plus azacitidine in patients with higher-risk myelodysplastic syndrome has been discontinued due to futility at a planned analysis.

John L. Marshall M.D., shares insights on health-related quality of life (HRQoL) findings from SUNLIGHT study presented at ESMO World Congress on Gastrointestinal Cancer (ESMO GI) 2023.

Committees have worked for the past 4 years to develop uniform definitions of immunotherapy resistance, but they are not yet universally used.

Nearly half of patients treated with zilucoplan were considered responders on Myasthenia Gravis Activities of Daily Living (MG-ADL) at the first week, suggesting a rapid onset of efficacy.

A review identified specificities that suggested that infections of respiratory syncytial virus (RSV) evolve chest tomography features.

The study also found that patients with a later best confirmed response to therapy demonstrated improved outcomes compared with patients who experienced an early best confirmed response.

A record low of 7.7% of Americans had no health insurance at the start of 2023; the American Academy of Pediatrics renewed its backing of gender care for children while requesting a research review; 2 lots of an oral contraceptive were recalled for possible reduction in effectiveness.

A panel of medical experts discuss the clinical and financial considerations surrounding the treatment of patients diagnosed with schizophrenia.

Social determinants of health impacting the treatment landscape for schizophrenia are discussed.