Video Series

Video 2 - "SunRISe-1: Examining Combination Therapy for HR NMIBC"

1) A medical urologist discusses the rationale and design of the SunRISe-1 phase 2 trial, which evaluates the combination of intravesical TAR-200 and systemic cetrelimab, as well as the TAR-200 and cetrelimab monotherapy arms, in patients with Bacillus Calmette-Guérin (BCG)-unresponsive high-risk non-muscle-invasive bladder cancer (HR NMIBC), focusing on key efficacy and safety endpoints.

Video 1 - "Comparing Long-Term Efficacy of Bladder-Preserving Therapies for NMIBC "

Neal Shore, MD, FACS, discuss the key efficacy outcomes reported for nadofaragene firadenovec (ADSTILADRIN) in the phase 3 trial for patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer (NMIBC) and compare these long-term results to other bladder-preserving therapies in this population.

Video 2 - "Payer Needs and Strategies for Evaluating and Covering PDTs"

Panelists delve into the data and the cost-saving evidence required by payers to cover prescription digital therapeutics (PDTs), outline the decision-making process followed by payers, and share best practices observed in real-world to ensure the successful implementation of PDTs.

Video 1 - "Differentiating PDTs from Wellness Apps and Evaluating Efficacy"

Diana Brixner, PhD, and Ashley Peterson, MHA, explore the distinctions between prescription digital therapeutics (PDTs) and wellness mobile apps, addressing the role of insurance coverage and the clinical validation requirements that payers consider when determining whether to cover PDTs as a treatment modality.

Video 13 - "Individualized Therapy for Specific Infections Associated with Bronchiectasis"

A medical expert discusses the various types of bacteria and fungi that can grow in the lungs and sputum of bronchiectasis patients, such as Pseudomonas aeruginosa, emphasizing the importance of an individualized approach to treatment, and notes that while fungal cultures may be positive, they may not always be clinically significant.

Video 11 - "Social Burden and Goals of Therapy for Patients with Bronchiectasis"

Pamela J. McShane, MD, explains her approach to diagnosing the underlying cause of bronchiectasis, which includes identifying cystic fibrosis in older patients, and emphasizes the importance of helping patients lead a normal life while managing their condition.

Video 11 - "Social Burden and Goals of Therapy for Patients with Bronchiectasis"

A medical professional addresses the social aspects of bronchiectasis, emphasizing patients' embarrassment due to productive coughing in public spaces like grocery stores and churches, as well as the psychological challenges of planning travel and vacations due to the unpredictability of exacerbations, which can lead to social isolation.

Video 14 - "Achieving Equitable Representation in Clinical Studies"

The panel has an in-depth discussion on improving diversity in clinical trials. They discuss ways to increase minority participation through community partnerships, including providing transportation, lodging, and other resources needed to enable participation.

Video 13 - "Measuring Implicit Bias"

Pam R. Taub, MD, FACC, FASPC, leads a discussion on implicit bias and mandated trainings for medical license renewal that help eliminate bias and address disparities.

Video 10 - "Bronchiectasis Exacerbation Management"

A medical professional explores the management of bronchiectasis exacerbations, detailing the significance of sputum color, the potential for hemoptysis, and the exacerbation of comorbidities such as COPD and asthma.

Video 13 - "Concluding Thoughts on Ph+ ALL Treatment"

Medical doctors discuss the future of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) and their five-year outlook for advancements and potential cures for the disease.

Video 12 - "The Future of Ph+ ALL Treatments"

Medical doctors discuss the future of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) and their five-year outlook for advancements and potential cures for the disease.

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