Video Series

Experts explore treatment considerations when treating patients with metastatic breast cancer with elacestrant, including dosing, patient selection, adherence, and treatment duration. Participants also discuss dose modifications, adherence concerns, and how they determine treatment failure.

Aaron Gerds, MD, MS, reviews the National Comprehensive Cancer Network (NCCN) guideline categories, including evidence, and recommendations for symptomatic high-risk myelofibrosis. He discusses considerations for selecting JAK inhibitors and the threshold for switching treatments based on responses.

Jessica Nance, MD, MS, discusses maximizing gene therapy efficiency by selecting vectors for gene size, tissue targeting, and low exposure, and focusing on precise promoters for expression.

Mirna Chehade, MD, MPH, discusses ongoing trials for emerging therapies in eosinophilic esophagitis (EoE), her views on the use of combination therapies, and the importance of shared decision-making for the chronic management of EoE throughout the different phases of a patient’s life.

Aaron Gerds, MD, MS, discusses key updates in the National Comprehensive Cancer Network (NCCN) guidelines for myelofibrosis, including new treatments such as momelotinib and refined recommendations for different patient populations. He reviews symptom management, spleen size, and supportive care measures for optimal patient outcomes.

Experts review groundbreaking insights from review the 2023 American Society of Hematology Annual Meeting and Exposition (ASH 2023) and discuss the paradigm shift in myeloma frontline treatments, exploring quads, bispecifics, and the dynamic evolution of therapeutic approaches.

Mirna Chehade, MD, MPH, discusses the challenges faced by patients with eosinophilic esophagitis (EoE), including the absence of predictive factors for personalized treatment, the social implications of dietary restrictions, and the need for invasive procedures, while emphasizing the importance of regularly scheduled follow-up visits to address medical, nutritional, and psychosocial factors for better outcomes.

Experts discuss the evolving landscape of multiple myeloma treatment, exploring real-world evidence's role in shaping the future and its impact on clinical decisions, rare subgroups, and treatment sequencing.

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