Opinion|Videos|April 30, 2025

HIV Viral Suppression: Clinical Significance and Impact on Patient Outcomes

A panelist discusses how viral suppression in HIV patients means achieving undetectable virus levels (below 50 or 20 copies per ml), which prevents immune system damage and transmission to others, summarized as "undetectable equals untransmissible" (U=U).

Episodes in this series

Viral Suppression in HIV Management

Key Themes:

  • Definition of Viral Suppression
    • Viral suppression means HIV viral load is below detectable levels on laboratory tests
    • Current laboratory standards define suppression as less than 50 copies/ml or less than 20 copies/ml
  • Clinical Significance
    • Suppression indicates virus is not replicating, preventing further immune system damage
    • Regular viral load monitoring is essential for confirming ongoing suppression
  • Transmission Prevention
    • Dr. Walmsley highlighted the "U=U" principle: "Undetectable equals Untransmissible"

Virally suppressed patients cannot transmit HIV to others, representing a major advancement

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