Opinion|Videos|January 26, 2024

Navigating the Multiple Myeloma Treatment Landscape

Renowned multiple myeloma specialists discuss challenges in treatment decisions, exploring real-world data's role, assessing risks in diverse populations, and interpreting cross-trial comparisons.

This is a video synopsis/summary of a Peer Exchange featuring Joshua Richter, MD; Rafat Abonour, MD; Faith Davies, MD; and Amrita Krishnan, MD.

Richter addresses the importance of real-world data (RWD) in understanding drug behavior in specific patient populations. Abonour emphasizes the need for better representation of African Americans in clinical trials and advocates for RWD to bridge this gap. Davies discusses the significance of RWD in assessing frail patients, acknowledging the limitations and variations in data collection standards. The conversation delves into the challenges of comparing trials directly and the role of indirect comparison studies, such as the MAIA (NCT02252172) vs SWOG S0777 (NCT00644228), with Krishnan highlighting the need for access to individual patient data for meaningful comparisons.

Video synopsis is AI-generated and reviewed by AJMC® editorial staff.

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