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Unmet Needs In CLL and SLL Treatment Management
Deborah Stephens, DO, shares unmet needs in the current treatment landscape of CLL and SLL.
EP: 1.Clinical Characteristics Distinguishing CLL and SLL
EP: 2.Quality of Life Impacted By CLL and SLL Diagnosis and Management
EP: 3.Evaluating Current Treatment Landscape of CLL and SLL
EP: 4.Unmet Needs In CLL and SLL Treatment Management
EP: 5.Indications and Considerations For BTK Inhibitor Use In CLL and SLL Management
EP: 6.Examining Safety and Efficacy of BTK Inhibitors In CLL and SLL Treatment
EP: 7.Determining Optimal CLL / SLL Therapy: Ibrutinib, Acalabrutinib and Zanubrutinib
EP: 8.Key Highlights From ASH 2023
EP: 9.Economic Burden Associated With BTK Inhibitor Use
EP: 10.Patient Education Driving BTK Inhibitor Treatment Adherence
EP: 11.Optimizing BTKi Treatment Strategies
EP: 12.Key Considerations for Treating Patients Diagnosed With CLL and SLL
This is a video synopsis/summary of a Peer Exchange involving Ryan Haumschild, PharmD, MS, MBA; Tara Graff, DO, MS; Ryan Jacobs, MD; Deborah Stephens, DO; and Jennifer Woyach, MD.
Stephens discusses how Bruton tyrosine kinase (BTK) inhibitors address unmet needs in chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) compared to previouschemotherapies with severe adverseeffects that impacted patients’ lives. Ibrutinib was a game changer as the first BTK inhibitor that patients could take as a pill at home. This ease of access and high efficacy servesa major unmet need. Even newer therapies still require in-person infusions unlike BTK inhibitors, which can be shipped to patients directly. This provides wider access with less frequent lab monitoring or clinic visits.
However, unmet needs remain since these drugs are not curative and must be taken continuously. Adverseeffects still occur, and resistance can develop after multiple lines of therapy. So while BTK inhibitors have helped patients live their liveswith minimal impact, areas needing work include finding a cure, further reducing adverseeffects, and overcoming resistance. A key benefit is the convenience and accessibility for patients.
Video synopsis is AI-generated and reviewed by AJMC® editorial staff.
Frameworks for Advancing Health Equity: Urban Health Outreach
May 9th 2024In the series debut episode of "Frameworks for Advancing Health Equity," Mary Sligh, CRNP, and Chelsea Chappars, of Allegheny Health Network, explain how the Urban Health Outreach program aims to improve health equity for individuals experiencing homelessness.
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Margin Status Likely Not a Factor in STS Recurrence
May 10th 2024The optimal negative margin required following surgical resection and perioperative radiotherapy for extremity soft tissue sarcoma (STS) remains up for debate, with investigators of a new study using Union for International Cancer Control classification to define resection margin.
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A Focus on Women: AUA Best Posters Highlight Female Athletes, Prenatal Care, and Women in Urology
May 9th 2024Three posters from the American Urological Association (AUA) 2024 Annual Meeting focused on urinary incontinence in female athletes, prenatal care for fetuses with spina bifida in California, and the experiences of women residents at the Brady Urological Institute.
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