Cardiovascular

Elevated blood pressure and stage 1 and 2 hypertension before age 40 puts young adults at higher risk for cardiovascular disease (CVD) events later in life compared to those with normal blood pressure, according to a new study published in JAMA.

The label change includes data from the LEADER trial, which showed that the same active ingredient, liraglutide, reduced major cardiovascular events when given at a lower dose.

Cardiovascular outcomes trials have changed type 2 diabetes drug development and added to the knowledge base, but some think these giant studies make therapies too costly and discourage innovation.

Amgen has announced that the price of its proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, evolocumab (Repatha), will be reduced by 60%, from an annual price of $14,100 down to $5850.

The analysis of data from EMPA-REG OUTCOME arrives as the FDA weighs the future of these large trials.

Patient preference should be considered because medications don't work if adherence is poor, the experts noted.

For 2017, New Jersey's largest insurer made particularly good progress in certain diabetes measures and in cancer screenings.

Black and Latino individuals are less likely than their white peers to develop early-onset atrial fibrillation (EOAF), yet these individuals experience higher rates of stroke, heart failure, and mortality from AF than do white patients. To date, little has been known about this paradox, as most research into EOAF focuses on white patients.

Heart failure hospitalization has been a target for accountable care organizations seeking to find ways to cut costs from the healthcare system. But it remains to be seen how many of the estimated 2 million patients would gain access to the device if it received an expanded indication and payer coverage.

Full results from the cardiovascular outcomes trial for dapagliflozin (Farxiga) will be presented at the American Heart Association annual meeting in November.

In the United States, a woman age 30 to 70 years of age has a 1 in 8 chance of dying from a noncommunicable disease (NCDs), putting the nation on par with low and middle-income countries, and setting it apart with Iceland among high-income countries, according to a report published Thursday in The Lancet.

The study by the National Institute on Aging produced a few surprises and was stopped early when aspirin showed no benefit.

The announcement comes with word from FDA touting the effectiveness of its efforts to advance digital health regulatory pathways.

The application is based on results presented in March at the 67th Scientific Session of the American College of Cardiology.

The analysis of patient records found no elevated risk of retinopathy among those using glucagon-like peptide-1 (GLP-1) receptor agonists to treat type 2 diabetes.

Serious vascular events in patients with diabetes can be prevented with aspirin use, according to results of the ASCEND (A Study of Cardiovascular Events iN Diabetes) trial, which were presented at the ongoing ESC Congress in Munich, Germany.

GOP senators have introduced legislation they say would protect provisions for preexisting conditions under the Affordable Care Act; Cigna shareholders have voted in favor of the acquisition of pharmacy benefit manager Express Scripts; and study results show that aspirin does not lower cardiovascular (CV) risk in the long-term.

A Health Affairs analysis showed a wide range of cost-effectiveness estimates for 30 of the most commonly prescribed cardiovascular drugs, suggesting that drug pricing is not consistently aligned with value.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Physician and patient predictors of hyperlipidemia screening and statin prescription at a large, multihospital regional health center based on electronic health record data.

Health plans continue to show interest in expanding outcomes-based contracts, according to an Avalere Health study that also found cardiovascular diseases, infectious diseases, and oncology represent the most common therapeutic areas to have these contracts.

Sulfonylureas are an older class of type 2 diabetes therapy but remain the most commonly prescribed antidiabetic drug after metformin.

Direct oral anticoagulants (DOACs) are associated with increased prescription costs. Actual practice data show a high switch rate and poor adherence among DOAC initiators that need to be addressed.

Findings from a 10-year research project show that implementing health initiatives at a population level can improve health and reduce the risk of heart disease for an entire community.

Public health messaging has typically focused on the volume of walking not the intensity. This study suggests for those with limited time, a faster pace could make a difference.