Diabetes

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Todd Brusko, PhD, of the Todd M. Brusko Laboratory at the University of Florida College of Medicine, discussed how knowledge of regulatory T-cells has grown and improved, and noted that research has now entered a phase of harnessing the potential of our immune system through specific cell populations to combat root causes of type 1 diabetes (T1DM).

Bernard Zinman, MD, the director of the Leadership Sinai Centre for Diabetes and the Sam and Judy Pencer Family Chair in Diabetes Research at Mount Sinai Hospital and the University of Toronto in Canada, discusses the new therapies, SGLT-2 inhibitors, that are now approved in the United States and European Union. These drug therapies have shown clinical benefits in both type 1 and type 2 diabetes, and may also improve cardiovascular outcomes for patients with type 2 diabetes

Jaakko Tuomilehto, MD, PhD, a professor of public health at the University of Helsinki in Finland provides global epidemiological data for T1DM and discusses the World Health Organization's Diabetes Mondiale (DiaMond) study. He compares the rates of incidences of T1DM among well-developed, high-income countries to low- and middle-income nations and takes note of the epidemiological trends.

In light of ongoing healthcare reform in the US, Sheldon Greenfield, MD, the executive co-director of the Health Policy Research Institute and Donald Bren Professor of Medicine at the University of California Irvine School of Medicine, shared his insights on the role of quality care measures in the management of diabetes, and weighed in on the advantages and disadvantages associated with implementing these tools.

Accounting for what is known about the association between diabetes and low testosterone in men, Rita Basu, MD, a professor of medicine at the Mayo Clinic in Rochester, MN provides her insights on the role of testosterone supplementation in men with diabetes, and notes how clinical and managed care perspectives are integrated in practice.

Cost-effectiveness analyses (CEAs) have real effects on therapeutic approaches for patients with type 2 diabetes mellitus (T2DM). Dr. Gilmer discusses how studies like the United Kingdom Prospective Diabetes Study (UKPDS) and the Diabetes Prevention Program (DPP) have affected how researchers and scientists evaluate the benefits of new treatments.