Eosinophilic Esophagitis (EoE)

The AJMC® Eosinophilic Esophagitis (EoE) compendium is a comprehensive resource for clinical news and expert insights for the chronic immune system disease. EoE is an allergic condition in which the esophagus becomes inflamed and cannot contract properly

FDA Approves Dupilumab as First Therapy for Eosinophilic Esophagitis

May 20th 2022, 7:56pm


Eosinophilic esophagitis is a chronic inflammatory disorder in which eosinophils, a type of white blood cell, proliferate in the esophagus, causing difficulties with eating and swallowing.

Dupilumab Improves Lung Function, Asthma Attacks in Children With Atopic Comorbidities

May 16th 2022, 4:30pm


Dupilumab improved lung function and reduced severe asthma exacerbation rates in children with moderate to severe asthma with or without atopic comorbidities.

Rare, Novel Chromosomal Duplication of Entire IL-33 Gene Documented in Case Study

May 15th 2022, 6:31pm


In their paper, the researchers detail the first, to their knowledge, case of a potential gain of function phenotype for IL-33 in a human.

Colette Romero on the Strategies Her Family Uses to Cope With EoE

May 13th 2022, 6:08pm


Colette Romero, whose child has eosinophilic esophagitis (EoE), describes some of the coping strategies her family uses to encourage her son to keep healthy.

EoE Research Examines Long-term Efficacy of PPIs in Responders

May 9th 2022, 8:15pm


A recent study sought to address what is known about proton pump inhibitors (PPIs) as a therapy for eosinophilic esophagitis and long-term outcomes in patients who respond to them as a way to guide treatment decisions.

Report Describes Case of Eosinophilic Enteritis Complicated by CMV

May 4th 2022, 2:08pm


The authors said that to their knowledge, this is the first report of cytomegalovirus (CMV) that developed during the treatment of eosinophilic enteritis in an adult.

Proton Pump Inhibitors Plus Food Elimination Diet Superior to Monotherapy in Refractory EoE

April 29th 2022, 10:30pm


A small retrospective study examined outcomes in patients with eosinophilic esophagitis (EoE) who did respond to solo therapies.

Patients With EoE Lack Effective, Targeted Therapies for Long-term Disease Control, Review Finds

April 19th 2022, 9:48pm


The lack of effective long-term control of eosinophilic esophagitis (EoE) highlights the unmet need for targeted systemic therapies.

Psychiatric Disease Risk Higher for Patients With EoE, Study Says

April 16th 2022, 9:02pm


Other gastrointestinal disorders and inflammatory diseases have also been linked to psychiatric disorders, but not much is known about the connection to eosinophilic esophagitis (EoE).

In Adults With EoE, Dilation May Mask Underlying Inflammation

April 15th 2022, 9:34pm


The study was conducted because information on the relationship between eosinophilic esophagitis (EOE) symptoms and biologic findings are limited, so researchers looked at the long-term effects of esophageal dilation, including patient-reported outcome (PRO) measures.