HIV

The AJMC® HIV compendium is a comprehensive resource for clinical news and expert insights for the condition, including disparities in care, prevention of infection among at-risk groups, and the importance of viral suppression.

Latest News

PrEP | Image credit: alimyakubov - stock.adobe.com
Higher Levels of PrEP Use Associated With Reduction in HIV Diagnoses

June 30th 2025

Making pre-exposure prophylaxis (PrEP) more accessible can help to decrease the incidence of HIV in the US.

PrEP | Image credit: Bowonpat - stock.adobe.com
Researchers Estimate PrEP Needed in the US Across Multiple Subgroups

June 24th 2025

Colleen Kelley, MD, MPH
Accessibility Important After FDA Approves Lenacapavir for PrEP: Q&A With Colleen Kelley, MD, MPH

June 20th 2025

Image credit: Yale School of Medicine
Lenacapavir Offers Promising Step Forward in HIV Prevention: Q&A With Onyema Ogbuagu, MBBCh, FACP, FIDSA

June 19th 2025

FDA Approved
Twice-Yearly Lenacapavir Approval Marks Major Milestone in Prevention of HIV

June 18th 2025

Clarifying USPSTF Recommendations for HIV Pre-Exposure Prophylaxis (PrEP)

This discussion focuses on how to address barriers and disparities as obstacles to using PrEP, with a focus on USPSTF PrEP guidelines and ACA Part 47 for payers and providers.

This multi-stakeholder roundtable panel discussion will focus on how to address barriers and disparities as obstacles to the use of PrEP, with a focus on increased understanding and education around US Preventive Services Task Force (USPSTF) PrEP guidelines and Affordable Care Act Part 47 for payers and providers.
Continuing Medical Education
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June 30th 2025

Navigating the HIV Treatment Frontier: Equipping Managed Care Professionals With Strategies for Innovation, Access, and Adherence

1.5 Credits / HIV/AIDS, Infectious Diseases
June 30th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology
June 30th 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

More News

PrEP for HIV Prevention: Essential for Ending the Epidemic, but Out of Reach for Many
July 24th 2018

PrEP for HIV Prevention: Essential for Ending the Epidemic, but Out of Reach for Many

Jaime Rosenberg
Despite pre-exposure prophylaxis (PrEP) being crucial for preventing new HIV infections and working toward an end to the epidemic, the treatment is still out of reach for many.
Urgent Change in Approach to HIV Pandemic Is Needed, Report Says
July 20th 2018

Urgent Change in Approach to HIV Pandemic Is Needed, Report Says

Jaime Rosenberg
According to a report, existing HIV tools and strategies are insufficient, and despite historic breakthroughs in maximizing prevention and treatment strategies, the HIV pandemic will likely continue to be a global challenge for the foreseeable future.
FDA Approves First Darunavir-Based Single-Tablet Regimen for HIV
July 18th 2018

FDA Approves First Darunavir-Based Single-Tablet Regimen for HIV

Jaime Rosenberg
Janssen announced the approval of Symtuza (darunavir 800 mg, cobistat 150 mg, emtricitabine 200 mg, and tenofovir alafenamide 10 mg) for the treatment of HIV-1 in treatment-naïve and certain virologically suppressed patients.
MANNA: Providing Nutritious Meals and a Sense of Community to People Living With HIV
July 13th 2018

MANNA: Providing Nutritious Meals and a Sense of Community to People Living With HIV

Jaime Rosenberg
Since 1990, MANNA has been providing nourishing meals and a sense of community to people living with HIV and other chronic diseases in Philadelphia.
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July 13th 2018

Modeling the Impacts of Restrictive Formularies on Patients With HIV

James Baumgardner, PhD Caroline Huber, MPH Mina Kabiri, PhD Lara Yoon, MPH Jacki Chou, MPP, MPL John Romley, PhD
Constraining access to HIV regimens can have significant implications for patients. This study examined the economic and health impacts of restrictive HIV formulary designs.
Mobile Health Intervention for HIV Improves Retention in Care, Patient Outcomes
July 11th 2018

Mobile Health Intervention for HIV Improves Retention in Care, Patient Outcomes

Jaime Rosenberg
Through the use of a smartphone app, researchers observed that participants became more engaged with their HIV care, resulting in improved linkage to and consistency of care, increased CD4 counts, and decreased viral loads.
HIV Vaccine Candidate Proves Safe, Induces Immune Response in Healthy Adults, Monkeys
July 7th 2018

HIV Vaccine Candidate Proves Safe, Induces Immune Response in Healthy Adults, Monkeys

Jaime Rosenberg
Research results from 2 studies found that the mosaic Ad26–based HIV vaccine regimens were both well-tolerated and induced a robust immune response against HIV in healthy adults and rhesus monkeys.
This Week in Managed Care: July 6, 2018
July 6th 2018

This Week in Managed Care: July 6, 2018

This week, the top managed care stories included a federal judge blocking Kentucky’s Medicaid work requirements; CMS announced it would launch a demonstration to encourage Medicare Advantage providers to take on more risk; and researchers identify racial disparities in HIV incidence and recommended a 5-part plan of action.
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July 5th 2018

Study Summary: Impact of Same-Day HIV Testing and ART Initiation on Patient Care and Outcomes

Koenig SP, Dorvil N, D
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July 5th 2018

Study Summary: Effect of Comorbid MDD on HIV Disease Profression

Owora AH. Major depression disorder trajectories, HIV disease progression: results from a 6-year outpatient clinic cohort. Medicine (Baltimore). 2018, 97(12):e0252. doi: 10.1097/MD.0000000000010252.
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July 5th 2018

Study Summary: Risk of Mother-to-Baby-HIV Trasmission Among Mothers Coinfected with Other STIs

Adachi K, Xu J, Yeganeh N, et al, NICHD HPTN 040 Study Team. Combined evaluation of sexually transmitted infections in HIV-infected pregnant women, infant HIV transmission. PLoS One. 2018, 13(1):e0189851. doi: 10.1371/journal.pone.0189851.
Identifying Missed Opportunities for HIV Testing in Clinical Settings
July 3rd 2018

Identifying Missed Opportunities for HIV Testing in Clinical Settings

Jaime Rosenberg
Pinpointing and eliminating missed opportunities for HIV testing and diagnosis in healthcare settings has the potential to reduce HIV transmission, especially among high-risk groups.
What We're Reading: Trauma Fees Inflate ED Bills; CDC Chief Switches View; Painkiller Shortages in Hospitals
July 2nd 2018

What We're Reading: Trauma Fees Inflate ED Bills; CDC Chief Switches View; Painkiller Shortages in Hospitals

AJMC Staff
Collected emergency department (ED) bills show that trauma fees are costly and swing widely; the head of the CDC has changed his mind about opposing the use of condoms and needle programs as ways to stop the spread of sexually transmitted diseases; EDs around the country are struggling with shortages of painkillers and cardiac drugs.
Researchers Highlight Disproportionate HIV Incidence Among African Americans, Recommend Plan of Action
June 29th 2018

Researchers Highlight Disproportionate HIV Incidence Among African Americans, Recommend Plan of Action

Jaime Rosenberg
African Americans are still disproportionately affected by HIV compared with other ethnic groups.
Increasing Awareness and Early Diagnosis on National HIV Testing Day
June 27th 2018

Increasing Awareness and Early Diagnosis on National HIV Testing Day

Jaime Rosenberg
As tomorrow marks National HIV Testing Day, over 400 organizations and clinics nationwide are spearheading efforts to promote testing.
Many People at Risk of Contracting HIV Are Not Screened Annually
June 24th 2018

Many People at Risk of Contracting HIV Are Not Screened Annually

Jaime Rosenberg
Many people at high risk of getting HIV—including those who inject drugs, gay and bisexual men, and partners of people with HIV—are not screened annually and experience delays in diagnosis.
Viral Suppression in People With HIV Associated With Reduced Cancer Risk
June 21st 2018

Viral Suppression in People With HIV Associated With Reduced Cancer Risk

Jaime Rosenberg
For people living with HIV who achieve viral suppression from antiretroviral therapy, there is a reduced risk of developing both AIDS-defining cancer and non-AIDS-defining cancer.
Walgreens, Greater Than AIDS Team Up With Health Organizations to Provide Free HIV Testing
June 13th 2018

Walgreens, Greater Than AIDS Team Up With Health Organizations to Provide Free HIV Testing

Jaime Rosenberg
On National HIV Testing Day on June 27, Walgreens and Greater Than AIDS will partner with over 200 health and community organizations to provide free HIV testing and information at Walgreens stores in over 180 cities.
NCI-Designated Cancer Centers Endorse Goal of Eliminating HPV-Related Cancers
June 13th 2018

NCI-Designated Cancer Centers Endorse Goal of Eliminating HPV-Related Cancers

Jaime Rosenberg
The 70 National Cancer Institute (NCI)-designated cancer centers underscored the importance of increased HPV vaccination and evidence-based screening, with the goal of eliminating cancers caused by the human papillomavirus (HPV).
Early ART Initiation Significantly Reduces Treatment Failure in Patients With HIV
June 8th 2018

Early ART Initiation Significantly Reduces Treatment Failure in Patients With HIV

Jaime Rosenberg
New study results have concluded that antiretroviral therapy (ART) initiation within 30 days of HIV diagnosis is associated with a significantly reduced risk of treatment dropout and failure.
Successful Management of HIV Is Outpacing That of Diabetes in Women
June 7th 2018

Successful Management of HIV Is Outpacing That of Diabetes in Women

Jaime Rosenberg
Among HIV-positive women with diabetes, HIV control has improved over time, but diabetes control has not.
PEPFAR Reaches 14 Million People With HIV Globally
May 31st 2018

PEPFAR Reaches 14 Million People With HIV Globally

Jaime Rosenberg
As this month marks the 15th anniversary, the US President’s Emergency Plan for AIDS Relief (PEPFAR) now supports over 14 million people globally with HIV treatment.
Study Will Assess Safety of HIV-to-HIV Kidney Transplantation
May 29th 2018

Study Will Assess Safety of HIV-to-HIV Kidney Transplantation

Jaime Rosenberg
The HOPE in Action Multicenter Kidney Study will examine the safety of HIV-to-HIV kidney transplantation.
Podcast: This Week in Managed Care—Impact of Hypertension Guideline Update and Other Health News
May 26th 2018

Podcast: This Week in Managed Care—Impact of Hypertension Guideline Update and Other Health News

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.
This Week in Managed Care: May 25, 2018
May 25th 2018

This Week in Managed Care: May 25, 2018

This week, the top managed care stories include the finding that new guidelines will mean the number of people with hypertension will soar; research finds that most diabetes apps don’t lower glycated hemoglobin; and a health plan announced its plan to fight housing instability.
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May 25th 2018

Study Summary: HIV-1 Resistance to Integrase Strand Transfer Inhibitors

You J, Wang H, Huang X, et al. Therapy-emergent drug resistance to integrase strand transfer inhibitors in HIV-1 patients: a subgroup meta-analysis of clinical trials. PLoS One. 2016, 11(8):e0160087. doi: 10.1371/journal.pone.0160087.
Early Initiation of Antiretroviral Therapy Can Prevent HIV-Related Brain Damage
May 23rd 2018

Early Initiation of Antiretroviral Therapy Can Prevent HIV-Related Brain Damage

Jaime Rosenberg
Neurological damage begins early in infection, particularly during untreated infection, and worsens with the continued absence of combination antiretroviral therapy (cART). However, initiating cART may halt further deterioration, emphasizing the importance of early cART.
FDA Warns of Neural Tube Birth Defects From HIV Drug Dolutegravir
May 21st 2018

FDA Warns of Neural Tube Birth Defects From HIV Drug Dolutegravir

Jaime Rosenberg
The FDA has warned of serious cases of neural tube birth defects involving the brain, spine, and spinal cord affecting babies born to women with HIV being treated with dolutegravir.
FDA Expands Indication for PrEP to Reduce Risk of HIV in Adolescents
May 18th 2018

FDA Expands Indication for PrEP to Reduce Risk of HIV in Adolescents

Jaime Rosenberg
The FDA has approved an expanded indication for Gilead Science’s emtricitabine/tenofovir disoproxil fumarate (Truvada) to reduce the risk of HIV in at-risk adolescents. Truvada for pre-exposure prophylaxis (PrEP) was first approved for the use in adults in 2012.
FDA Releases Draft Guidance on HIV Treatment Development For Pediatric Patients
May 16th 2018

FDA Releases Draft Guidance on HIV Treatment Development For Pediatric Patients

Jaime Rosenberg
The FDA has drafted new recommendations on the development of drugs to treat pediatric patients with HIV meant to be applied on a global scale.
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