Lupus

Women with systemic lupus erythematosus (SLE) were twice as likely to experience carotid plaque buildup during the 5 years of this study.

Investigators found anti-ribosomal P protein antibodies, a serological marker for systemic lupus erythematosus (SLE), were linked with higher ferritin levels, independent of interleukin 6 levels.

Patients who took supplements had improvements, although they did not become apparent until patients had been taking supplements for a year.

Patients with SLE had higher levels of Wnt5A if they were experiencing active disease.

Dutch investigators found a screening questionnaire might be a good tool to identify patients warranting further testing for systemic lupus erythematosus (SLE).

Five gene hubs were identified, with one in particular appearing to correlate strongly with the pathogenesis of lupus nephritis.

A re-evaluation of patients found most had intermediate lupus erythematosus, even though the vast majority were initially diagnosed with the limited-cutaneous form of the disease.

In both blood and urine samples, patients with systemic lupus erythematosus and renal involvement were found to have higher levels of interleukin-35 compared with patients with systemic lupus erythematosus and no known renal involvement.

The report suggests childcare concerns could be a significant factor keeping Black women from attending weekly workshops.

Patients with lupus nephritis (LN) were found to have as much as twice the inpatient hospitalizations of patients with systemic lupus erythematosus without LN.

Cost increases were particularly pronounced among patients with severe systemic lupus erythematosus (SLE), the study found.

With no single biomarker for systemic lupus erythematosus, investigators wanted to investigate whether there is a connection between mean platelet volume and the disease.

In patients refractory to conventional therapy, the combination resulted in a 70% reduction in a key biomarker compared with placebo.

An abnormal retention of mitochondria can trigger the cascade of inappropriate and harmful immune activity that is characteristic of lupus, the report said.

The issue of systemic lupus erythematosus (SLE) is particularly important in Asia, because patients there suffer from more severe disease and damage compared with patients in Western countries.

An international group of researchers devised updated guidelines on the management and treatment of cutaneous lupus erythematosus (CLE).

A new study suggests the lower-cost, more patient-friendly assessment method may be a useful tool for clinicians.

This new study adds to the literature by giving the first long-term data in these populations.

A minority of patients will experience flares, but in most cases reintroduction of therapy will result in remission.

Intravenous belimumab had benefits, but also resulted in more health care utilization due to the nature of its administration.

Treat-to-target has long been used in adults, but a new study finds it is warranted in pediatric cases, too.

Five case reports suggested the anti-BAFF monoclonal antibody was effective at reducing disease activity scores for adults who have neuropsychiatric systemic lupus erythematosus (NPSLE).

A case report details the presentation of systemic lupus erythematous in a young, previously healthy individual.

Patients with systemic lupus erythematosus (SLE) said they still suffered significant pain and fatigue, even though they reported high rates of satisfaction with their therapies.

While an association was found between dementia and the most common form of lupus, links to other autoimmune diseases—rheumatic arthritis, Sjögren’s syndrome, and Behcet’s disease—were not found.