Lupus

With no single biomarker for systemic lupus erythematosus, investigators wanted to investigate whether there is a connection between mean platelet volume and the disease.

In patients refractory to conventional therapy, the combination resulted in a 70% reduction in a key biomarker compared with placebo.

An abnormal retention of mitochondria can trigger the cascade of inappropriate and harmful immune activity that is characteristic of lupus, the report said.

The issue of systemic lupus erythematosus (SLE) is particularly important in Asia, because patients there suffer from more severe disease and damage compared with patients in Western countries.

An international group of researchers devised updated guidelines on the management and treatment of cutaneous lupus erythematosus (CLE).

A new study suggests the lower-cost, more patient-friendly assessment method may be a useful tool for clinicians.

This new study adds to the literature by giving the first long-term data in these populations.

A minority of patients will experience flares, but in most cases reintroduction of therapy will result in remission.

Intravenous belimumab had benefits, but also resulted in more health care utilization due to the nature of its administration.

Treat-to-target has long been used in adults, but a new study finds it is warranted in pediatric cases, too.

Five case reports suggested the anti-BAFF monoclonal antibody was effective at reducing disease activity scores for adults who have neuropsychiatric systemic lupus erythematosus (NPSLE).

A case report details the presentation of systemic lupus erythematous in a young, previously healthy individual.

Patients with systemic lupus erythematosus (SLE) said they still suffered significant pain and fatigue, even though they reported high rates of satisfaction with their therapies.

While an association was found between dementia and the most common form of lupus, links to other autoimmune diseases—rheumatic arthritis, Sjögren’s syndrome, and Behcet’s disease—were not found.

A 4-biomarker panel can help ensure rheumatoid arthritis (RA) is accurately diagnosed, according to study results published in Arthritis Research & Therapy.

Previous studies have suggested that inflammatory diseases such as rheumatoid arthritis (RA) can increase the risk for dementia and that tumor necrosis factor agents may have a role in preventing the incidence of dementia.

Researchers explored the risk of cardiovascular disease (CVD) as it relates to factors like excess weight, disease evolution time, and clinical activity.

A new study has identified 4 subgroups of patients with arthritis based on their 24-hour activity-sleep profiles, which may allow for tailored interventions to support patients with arthritis.

Most people with systemic lupus erythematosus and inflammatory arthritis, who use medications that make them immunosuppressed, are not necessarily at greater risk of hospitalization from coronavirus disease 2019 (COVID-19), according to 2 studies.

Transferring from pediatric to adult care can result in difficulties for patients with childhood-onset systemic lupus erythematosus.