Lupus

The AJMC® Lupus compendium is a comprehensive resource for clinical news and expert insights for the inflammatory disease that occurs when the immune system attacks its own tissues.

Latest News

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Top 5 Most-Read Lupus Articles of 2022

December 27th 2022

The top 5 most-read articles on lupus of 2022 included the role of B cells in systemic lupus erythematosus (SLE), the diagnostic journey of women with SLE, future therapies for cutaneous lupus erythematosus (CLE), and more.

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Case Report Details Rare Case of SLE With Cutaneous Leukocytoclastic Vasculitis

December 14th 2022

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Physical Activity Benefits People With SLE, but Many Do Not Meet WHO Guidelines

December 10th 2022

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New Data Suggest Biomarker for SLE Therapy Response

December 6th 2022

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Belimumab Provides Benefit in Cutaneous Lupus Erythematosus, With or Without SLE

November 16th 2022

More News

Researchers Discover Link Between Platelet Volume, Systemic Lupus Erythematosus
October 31st 2021

Researchers Discover Link Between Platelet Volume, Systemic Lupus Erythematosus

Christine Blank
With no single biomarker for systemic lupus erythematosus, investigators wanted to investigate whether there is a connection between mean platelet volume and the disease.
doctor writing script
October 25th 2021

Phase 2 Study Suggests Belimumab After Rituximab Leads to Improvement in SLE

Jared Kaltwasser
In patients refractory to conventional therapy, the combination resulted in a 70% reduction in a key biomarker compared with placebo.
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October 24th 2021

Altered Red Blood Cell Process May Contribute to Lupus, Study Says

AJMC Staff
An abnormal retention of mitochondria can trigger the cascade of inappropriate and harmful immune activity that is characteristic of lupus, the report said.
Researchers Describe Possible Mechanism for Distorted Cognition in SLE
October 24th 2021

Researchers Describe Possible Mechanism for Distorted Cognition in SLE

AJMC Staff
The issue of systemic lupus erythematosus (SLE) is particularly important in Asia, because patients there suffer from more severe disease and damage compared with patients in Western countries.
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October 14th 2021

New Guidelines Include Updates for CLE Treatment, Management

Gianna Melillo
An international group of researchers devised updated guidelines on the management and treatment of cutaneous lupus erythematosus (CLE).
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October 1st 2021

Neuromuscular Ultrasonography May Have Potential in Assessing SLE

Jared Kaltwasser
A new study suggests the lower-cost, more patient-friendly assessment method may be a useful tool for clinicians.
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September 27th 2021

Belimumab Has Favorable Safety, Efficacy in Patients With SLE

Jared Kaltwasser
This new study adds to the literature by giving the first long-term data in these populations.
Medication in pill box
September 25th 2021

Study: Immunosuppressant Withdrawal Feasible, Safe for Many Patients With SLE and Lupus Nephritis

Jared Kaltwasser
A minority of patients will experience flares, but in most cases reintroduction of therapy will result in remission.
Picture of IV bag
September 23rd 2021

IV Belimumab for SLE Reduces Flare-Ups, Oral Corticosteroid Use

Jared Kaltwasser
Intravenous belimumab had benefits, but also resulted in more health care utilization due to the nature of its administration.
Pediatric Asian patient
September 17th 2021

Treat-to-Target Strategy Has Treatment Potential in Pediatric Lupus Nephritis

Jared Kaltwasser
Treat-to-target has long been used in adults, but a new study finds it is warranted in pediatric cases, too.
Immune system graphic
September 15th 2021

Belimumab Shows Promise in Small Cohort of Adults With NPSLE

Jared Kaltwasser
Five case reports suggested the anti-BAFF monoclonal antibody was effective at reducing disease activity scores for adults who have neuropsychiatric systemic lupus erythematosus (NPSLE).
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September 8th 2021

Case Report Underscores Varied Nature of SLE Presentation

Gianna Melillo
A case report details the presentation of systemic lupus erythematous in a young, previously healthy individual.
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September 1st 2021

Therapy Satisfaction High Among Patients With SLE, Although Burdens Remain

Jared Kaltwasser
Patients with systemic lupus erythematosus (SLE) said they still suffered significant pain and fatigue, even though they reported high rates of satisfaction with their therapies.
Dementia Tied to Most Common Form of Lupus, Study Finds
March 17th 2021

Dementia Tied to Most Common Form of Lupus, Study Finds

Larry Hanover
While an association was found between dementia and the most common form of lupus, links to other autoimmune diseases—rheumatic arthritis, Sjögren’s syndrome, and Behcet’s disease—were not found.
Researchers Identify 4 Novel Biomarkers to More Accurately Diagnose RA
January 29th 2021

Researchers Identify 4 Novel Biomarkers to More Accurately Diagnose RA

Jaime Rosenberg
A 4-biomarker panel can help ensure rheumatoid arthritis (RA) is accurately diagnosed, according to study results published in Arthritis Research & Therapy.
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January 2nd 2021

Dementia in Patients With RA Lower in Those Using Biologics, Study Says

AJMC Staff
Previous studies have suggested that inflammatory diseases such as rheumatoid arthritis (RA) can increase the risk for dementia and that tumor necrosis factor agents may have a role in preventing the incidence of dementia.
Patients With Systemic Lupus Erythematosus Have Higher Cardiometabolic Risk for CVD
December 21st 2020

Patients With Systemic Lupus Erythematosus Have Higher Cardiometabolic Risk for CVD

Jaime Rosenberg
Researchers explored the risk of cardiovascular disease (CVD) as it relates to factors like excess weight, disease evolution time, and clinical activity.
Sleep, alarm clock
October 14th 2020

Patterns of Sleep and Activity Among Adults With Arthritis

Laura Joszt, MA
A new study has identified 4 subgroups of patients with arthritis based on their 24-hour activity-sleep profiles, which may allow for tailored interventions to support patients with arthritis.
Hospital hall
August 28th 2020

Patients With Lupus, Inflammatory Arthritis Have Similar Risk of COVID-19 Hospitalization as General Population

Laura Joszt, MA
Most people with systemic lupus erythematosus and inflammatory arthritis, who use medications that make them immunosuppressed, are not necessarily at greater risk of hospitalization from coronavirus disease 2019 (COVID-19), according to 2 studies.
Transitioning Adolescents With Lupus From Pediatric to Adult Care
July 23rd 2020

Transitioning Adolescents With Lupus From Pediatric to Adult Care

Laura Joszt, MA
Transferring from pediatric to adult care can result in difficulties for patients with childhood-onset systemic lupus erythematosus.
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