Nasal Polyps

The AJMC® Nasal Polyps compendium is a comprehensive resource for clinical news and expert insights for the condition, which is caused by chronic inflammation.

Mepolizumab Associated With Significant Improvement of Chronic Rhinosinusitis With Nasal Polyps, Comorbidities

January 26th 2022, 6:00pm

Article

Mepolizumab was found to reduce nasal polyp size and nasal obstruction in patients with chronic rhinosinusitis with nasal polyps regardless of the presence of potentially exacerbating comorbidities.

Endoscopic Sinus Surgery With Medical Therapy Effective for Chronic Rhinosinusitis With Nasal Polyps

January 22nd 2022, 7:00pm

Article

Patients with chronic rhinosinusitis with nasal polyps were found to benefit more from the combination of endoscopic sinus surgery plus medical therapy vs medical therapy alone, although the minimal clinically important difference was not met.

Dupilumab Linked With Significantly Improved Patient Outcomes in Severe Chronic Rhinosinusitis With Nasal Polyps

January 19th 2022, 9:00pm

Article

Patients with severe chronic rhinosinusitis with nasal polyps achieved significant improvements in health-related quality of life (HRQOL) and general health status with dupilumab treatment after 52 weeks.

Air Pollution Exposure Found to Exacerbate Severity of Chronic Rhinosinusitis With Nasal Polyps

January 13th 2022, 9:30pm

Article

Short-term exposure to several different types of air pollution was found to significantly increase disease severity in patients with chronic rhinosinusitis with nasal polyps.

Immunoglobulin Levels Linked With Nasal Polyp Development

January 10th 2022, 7:00pm

Article

Local immunoglobulin levels were found to be significantly higher in polyp tissue specimens, but not in the blood, of patients with nasal polyps.

Risk of Chronic Rhinosinusitis With Nasal Polyps Greater in Patients With Diabetes

January 8th 2022, 6:00pm

Article

A significant link was found regarding incidence of diabetes and chronic rhinosinusitis (CRS) with nasal polyps, whereas CRS without nasal polyps was not associated with diabetes.

Evaluating Dupilumab for Placement in a Value-Based Health Plan

May 10th 2021, 5:45pm

Article

Dupilumab is effective for atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyps, but a recent presentation noted the payer challenge in placing the biologic in an optimal tier.

Review Probes Role of Eosinophils in Chronic Rhinosinusitis With, Without Polyps

January 8th 2021, 5:10pm

Article

A review explored the potential role of eosinophils and their mediators in the pathophysiology of chronic rhinosinusitis (CRS) subtypes.

Subgroup Analysis Confirms Safety, Efficacy of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps

December 19th 2020, 2:30pm

Article

The analysis reviewed the safety and efficacy among patients in Japan to confirm the findings of the overall study population.

Immunological Characteristics as Potential Treatment Targets in Refractory CRS With Nasal Polyps

October 9th 2019, 5:00pm

Article

The aim of this study was to assess cytokine levels in patients with refractory chronic rhinosinusitis with nasal polyps and to identify inflammatory markers associated with certain subtypes.