Nasal Polyps

The AJMC® Nasal Polyps compendium is a comprehensive resource for clinical news and expert insights for the condition, which is caused by chronic inflammation.

Dupilumab Reduces OCS Dosage, Improves Lung Function for Asthma, CRSwNP

May 22nd 2022, 3:15pm


Dupilumab was associated with reductions in exacerbations and oral corticosteroids (OCS) dosage, as well as improved lung function, in patients with OCS-dependent asthma with and without comorbid chronic rhinosinusitis with nasal polyps.

Chitosan-Based Gel Found to Lower Risk of Wound Infection, Synechia After Nasal Polyps Surgery

May 20th 2022, 5:45pm


Use of a chitosan-based gel dressing after endoscopic sinus surgery for nasal polyps was found to reduce risk of wound infection and synechia in patients, although no difference was observed regarding granulations.

Dupilumab Improves Lung Function, Asthma Attacks in Children With Atopic Comorbidities

May 16th 2022, 4:30pm


Dupilumab improved lung function and reduced severe asthma exacerbation rates in children with moderate to severe asthma with or without atopic comorbidities.

Improved Sense of Smell Achieved With Biologics for CRS With Nasal Polyps, Asthma

May 12th 2022, 12:20pm


Patients with comorbid chronic rhinosinusitis (CRS) with nasal polyps and severe asthma reported significant improvement in their sense of smell when treated with the biologics omalizumab, mepolizumab, reslizumab, or benralizumab, with no significant differences observed between the treatment groups.

Experts Provide Overview of CRSwNP, Available Biologic Treatments

May 9th 2022, 4:52pm


Katharine Rimes, PharmD, and John Bosso, MD, discussed updates in management of chronic rhinosinusitis with nasal polyps at the 2022 Asembia Specialty Pharmacy Summit.

Machine Learning Identifies Predictors of Revision Endoscopic Sinus Surgery

May 5th 2022, 6:20pm


A machine learning approach identified age and several comorbidities, such as nasal polyps and asthma, as being associated with revision endoscopic sinus surgery among patients with chronic rhinosinusitis.

Clinical Improvement of AERD Achieved With Dupilumab Use for Asthma, CRS With Nasal Polyps

May 3rd 2022, 6:25pm


Patients with aspirin-exacerbated respiratory disease (AERD) who initiated treatment with dupilumab as an add-on asthma or chronic rhinosinusitis with nasal polyps therapy reported rapid clinical improvement that was sustained after 3 months.

HPV Infection May Increase Risk of Developing CRS With Nasal Polyps

April 30th 2022, 6:25pm


Presence of human papillomavirus (HPV) was significantly associated with incidence of chronic rhinosinusitis with nasal polyps (CRSwNP), although no differences in disease severity were observed among HPV-positive and HPV-negative patients with CRSwNP.

Real-world Patients Show Significant Improvement With Dupilumab for CRS With Nasal Polyps

April 28th 2022, 7:15pm


Use of dupilumab was associated with significant improvement in clinical symptoms of chronic rhinosinusitis (CRS) with nasal polyps among real-world patients in Canada, with benefits shown to be similar to that observed in randomized clinical trials.

Surveyed Patients Identify Unmet Needs in CRS With Nasal Polyps

April 23rd 2022, 6:20pm


Patients with chronic rhinosinusitis (CRS) with nasal polyps identified several unmet needs regarding their condition, particularly a lack of public and physician awareness on disease burden and poor sleep quality.