Bradley J. Monk, MD, FACS, FACOG, discusses how comprehensive molecular testing in ovarian cancer has evolved to include BRCA, folate receptor alpha, and emerging biomarkers like HER2 and CCNE1 while addressing challenges in education, reimbursement, and tumor heterogeneity that impact widespread adoption.
April 28th 2025EP. 1: The Role of Guidelines on Molecular Testing in Ovarian Cancer
A panelist discusses how National Comprehensive Cancer Network (NCCN) guidelines have influenced molecular testing in ovarian cancer, highlighting the importance of biomarkers like BRCA genes for treatment decisions, prognostic information, and family prevention strategies.
April 28th 2025EP. 2: FRα Biomarker Testing in Patients With Ovarian Cancer
A panelist discusses how folate receptor alpha (FRα) expression testing plays a crucial role in determining eligibility for mirvetuximab soravtansine (an antibody-drug conjugate therapy), emphasizing the importance of comprehensive biomarker testing at diagnosis rather than piecemeal testing.