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A single-blind, parallel, randomized clinical trial found that a continuous positive airway pressure (CPAP) machine was more effective in normalizing polysomnographic parameters and improving quality of life in patients with mild obstructive sleep apnea (OSA) compared with the mandibular advancement device.

A recent cohort study found that two-thirds of patients could transmit SARS-CoV-2 at 5 days since their symptoms began; the median infectiousness duration in the sample was 5 days.

Despite intranasal corticosteroid (INCs) being a treatment mainstay for chronic rhinosinusitis with nasal polyps, there are ongoing high rates of nonadherence, which can affect treatment efficacy, according to this study’s authors.

Researchers found automated foot strike detection is viable for smartphone-based fall risk classification in patients with lower limb amputations.

CDC Director Rochelle Walensky, MD, MPH, called public guidance during the COVID-19 pandemic “confusing and overwhelming”; CVS, Walgreens, and Walmart were ordered to pay $650.6 million to 2 Ohio counties after improperly dispensing prescription painkillers; a new screening method can detect extra or missing chromosomes in embryos and fetuses within hours.

Investigator Global Assessment score of very severe atopic dermatitis (AD) was associated with dupilumab discontinuation due to adverse effects, although generally adequate 1-, 2-, and 3-year drug survival rates were also observed.

Most participants were able to complete the assessments at home, and their scores correlated well with in-clinic assessments.

Adult patients from dermatology clinics affiliated with 2 Midwest universities were evaluated for their ability to differentiate skin cancer by sight and for their skin cancer knowledge.

The FDA Wednesday approved betibeglogene autotemcel (Zynteglo), the first cell-based gene therapy for the treatment of adult and pediatric patients with beta-thalassemia who require regular red blood cell transfusions.

A new case report highlights the potential benefits of risk assessment for women with a family history of autoimmune diseases, such as systemic lupus erythematosus (SLE), who are considering the human papillomavirus (HPV) vaccine.

A study found that adolescents who were more physically active had better sleep quality and heart rate variability than those who were sedentary.

Value management, theranostics, clinical trial access, and a mobile pharmacy are major innovations being integrated into independent community oncology practices, as highlighted at the Quality Cancer Care Alliance Summer 2022 National Leadership Summit.

Patient engagement solutions facilitate active care participation, but several myths persist that hinder their adoption and implementation.

A new FDA rule will allow hearing aids to be purchased without prescriptions; the FDA has received more than 48,000 reports of faulty Philips respiratory devices between May and July; HHS has extended postpartum Medicaid in Hawaii, Maryland, and Ohio.

The new report reverses previous research suggesting that White men who consumed large amounts of gamey meat and rich foods were most at risk.

Treatment with anti-interleukin (IL)-17A inhibitors for psoriasis consistently improved outcomes across primary and secondary endpoints compared with all other approved biologics, and researchers also found differences between anti-IL-17A inhibitors.

A new report offers insights from a multidisciplinary team of experts on intrahepatic cholangiocarcinoma (iCCA).

Anchalee Avihingsanon, MD, PhD, HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand, is principal investigator of the ALLIANCE trial.

While noting that providers and their patients should be aware of the potential risk, the researchers underscored that the risk of new-onset psoriasis due to tumor necrosis factor-α inhibitor (TNFi) treatment appears to be rare and that strategies do not need to change for patients with immune-mediated inflammatory diseases such as inflammatory bowel disease (IBD) and/or rheumatoid arthritis (RA).

Entresto (sacubitril/valsartan) is approved for use in adult and pediatric heart failure, and previous research shows it to be cost-effective in the long term.

The case describes hemophagocytic lymphohistiocytosis (HLH), which occurred in a young boy in Italy with spinal muscular atrophy, who was treated with onasemnogene abeparvovec.

The Institute for Value-Based Medicine series visits Texas Oncology in Austin.

Korean patients with type 2 diabetes (T2D) who had reduced levels of estimated glomerular filtration rate and/or proteinuria, 2 hallmarks of diabetic kidney disease, had a greater risk of developing Parkinson disease.

Despite the Hospital Transparency Rule being in effect, the majority of 340B hospitals are not reporting their prices for top services and drugs, and those that have, reported on “egregious” markups, said Ted Okon, MBA, executive director, Community Oncology Alliance.

President Joe Biden is anticipated to sign the $750 billion climate, health care, and tax legislation into law today; the United Kingdom is first to approve Moderna’s updated COVID-19 vaccine targeting both the original and Omicron variants; nearly 2000 mental health employees of Kaiser Permanente are on strike over staffing shortages.

Infants born between the 23rd and 25th weeks of pregnancy, classified as extremely low gestational age newborns, are surviving in increasing numbers, note study authors, and with that is growing clinical interest in their long-term sequelae, including pulmonary hypertension (PH).