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As a neurodegenerative disease, secondary progressive multiple sclerosis (SPMS) may lead to a degradation of cognition skills as the disease progresses.

Researchers review pulmonary function testing measures that span 4 categories that can assess the respiratory muscle dysfunction that happens in diseases like spinal muscular atrophy (SMA).

Researchers found abnormal coherence patterns in survivors of childhood polio.

Amid the coronavirus disease 2019 pandemic, patients with Parkinson disease reporting feelings of loneliness were found to experience greater severity of symptoms.

The analysis reviewed the safety and efficacy among patients in Japan to confirm the findings of the overall study population.

Their work may help to further understanding of the molecular mechanisms of hypomethylating agents (HMAs) and offer a guide for determining which patients are likely to respond to such treatment.

Giving patients icosapent ethyl, or Vascepa, led to a 52% reduction of the total patient-reported symptom outcome prevalence score as compared with a 24% decline for outpatients who received usual care.

Bringing together genetic work with social determinants of health can improve understanding of factors associated with ESKD disparities, said Adriana Hung, MD, MPH, associate professor of medicine at Vanderbilt University, and Bryce Rowan, a statistical genetic analyst.

The FDA Friday issued the second Emergency Use Authorization (EUA) for a coronavirus disease 2019 (COVID-19) vaccine, this one to Moderna, as the pandemic reached critical stress points across the country, especially in California.

Compared with adalimumab, sarilumab elicited greater improvements in health-related quality of life (QoL), particularly in patients with high levels of interleukin-6 (IL-6).

A new study validates the application of duplex sequencing in detecting mutations caused by chemical carcinogens.

Bradley Monk, MD, FACOG, FACS, clinician at Arizona Oncology, professor at the University of Arizona and Creighton University in Phoenix, discusses the reimbursement of PARP inhibitors in ovarian cancer.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Several states should expect fewer doses next week of the Pfizer/BioNTech coronavirus disease 2019 vaccine; a new analysis finds that prescription opioid use has dropped by 60% since 2011; availability of intensive care unit (ICU) beds in Southern California reaches 0%.

For patients who are resistant to hypomethylating agent (HMA) treatment, there are no formal treatment recommendations, but several options, spanning from novel HMAs to chemotherapy, have been or are currently being studied in the setting.

Four principal themes emerged in this study, describing why Latino/a and Black transgender women and men who have sex with men discontinued their preexposure prophylaxis (PrEP) to prevent HIV.

Patient plasma samples from this study show residual circulating tumor DNA (ctDNA) correlates with a poor prognosis in women with early-stage breast cancer, explained Alexey Aleshin, MD, senior medical director of Oncology at biotech giant Natera.

After a daylong meeting, an FDA advisory panel agreed that the second vaccine in the United States to prevent coronavirus disease 2019 (COVID-19) should be put forward for use.

Physicians will soon have a more complex set of options when treating patients with multiple myeloma (MM), but the authors of a new review article argued clinicians will need to take a pragmatic approach.

NSCLC patients who developed immune-related adverse events during immunotherapy showed longer overall survival and progression-free survival than patients who did not.

A 5-phase program designed to increase knowledge among patients with heart failure has shown promise in more effective disease management and hospital readmission reduction.

Eli Lilly & Co is set to acquire Prevail Therapeutics Inc for almost $1 billion; Pfizer’s coronavirus disease 2019 vaccine vials found to contain extra doses; a new treatment has been approved for patients with advanced breast cancer.

Older adults are often at greater risk for adverse events from treatments, but they can also be excluded from randomized controlled trials (RCTs), making it difficult to know if findings are generalizable to this population.

Both clinical and physician-based factors play a role in the risk of a patient with hematologic malignancies ending up in the ICU.

There are several signs characteristic of obstructive sleep apnea (OSA) in children and adolescents, but a sleep study interpreted according to pediatric standards is the only way to properly diagnose conditions such as sleep apnea, restless leg syndrome, or primary snoring in these populations.

Although a vaccine against coronavirus disease 2019 (COVID-19) is now in the fold, Americans should expect to remain in their current work environment in the short term, with potential long-term implications spanning the next 5 years.

Samples show certain subgroups of men with prostate cancer are more receptive to radiation therapy; FDA grants emergency use authorization to an at-home coronavirus disease 2019 (COVID-19) test; Anthony Fauci, MD, says COVID-19 herd immunity is possible by spring 2021.