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FDA significantly restricts the use of 2 COVID-19 monoclonal antibody treatments ineffective against the Omicron variant; an expert panel advises the Israeli government to offer a fourth COVID-19 vaccine dose to adults; there was a substantial increase in visits for mental health and substance abuse among physicians with no prior history during the pandemic.

The new one-page tool can be completed about 20 minutes faster than the older form, but it is also more accurate, investigators said.

In this poster presented at the 2022 ASCO Gastrointestinal Cancers Symposium, minimal residual disease (MRD) status as detected by postsurgery plasma cell-free DNA continued its strong track record of being a reliable predictor of disease progression in colorectal cancer (CRC).

Although men and women with advanced kidney disease experienced physical and mental declines in health-related quality of life (QOL), men’s declines occurred at a significantly faster rate, researchers concluded.

Researchers in Turkey analyzed the impacts of mask and disinfectant use among patients with confirmed migraine diagnoses.

Researchers examined differences in lung cancer screening and follow-up rates among individuals residing in Hawaii.

David R. Stukus, MD, FACAAI, of Nationwide Children's Hospital and The Ohio State University College of Medicine, and a board member of the American College of Allergy, Asthma & Immunology, discusses guidelines for eosinophilic esophagitis, as well as some disease patterns that may occur.

Findings presented at the 2022 ASCO Gastrointestinal Cancers Symposium showed no significant differences in tissue and plasma genomic profiles of patients with early-onset and late-onset colorectal cancer, but a greater enrichment of the BRCA1 and PTEN mutations were noted in the tissue of those with early-onset disease.

Results of a study carried out in Iran found those with a recent history of depressive disorders were more likely to suffer from polypharmacy, or taking 5 or more medications concurrently.

Women in the study were 3 times more likely to be affected by rheumatoid arthritis (RA) and nearly 4 times more likely to develop hypothyroidism, compared with men.

The CDC is working to change its definition of being fully vaccinated against COVID-19; a study finds that men who tested positive for COVID-19 showed a short-term decline in fertility; a nonprofit group of scientists seeks to optimize the clinical trial process and reduce cost.

According to a recent study, nearly 50% of patients with connective tissue disease, such as lupus, died when sepsis occurred.

One of the long-term effects of COVID-19 may be small fiber neuropathy in the ocular surface causing similar symptoms to dry eye disease and diabetic neuropathy, a recent study found.

In this column, an endocrinologist discusses the growing problem of liver disease and new options at their disposal, including vibration-controlled transient elastography.

Predictive markers may make it easier to figure out which patients require the often costly and invasive measures needed to confirm the coronary complication in patients with systemic lupus erythematosus.

Patients with chronic rhinosinusitis with nasal polyps were found to benefit more from the combination of endoscopic sinus surgery plus medical therapy vs medical therapy alone, although the minimal clinically important difference was not met.

Among the 3 methods used across 478 samples included in the study, next-generation sequencing provided the most favorable results.

A review of 3 common risk assessment tools for pulmonary arterial hypertension (PAH) found they successfully predict survival for up to 5 years after initial diagnosis.

In this recent CDC report, data show decreases in new HIV diagnoses in Lesotho, in Africa, among adolescent girls and young women attending antenatal care.

The severity of excessive daytime sleepiness correlated with the prevalence of Parkinsonian-like symptoms in adults aged 50 to 64, but further research is needed to determine the mechanisms behind the findings.

Among the most notable findings were that acute generalized exanthematous pustulosis is typically triggered by antimicrobial agents and may be associated with complications of the liver or kidney for some patients.

Edward W. Cowen, MD, MHSc, senior clinician and acting branch chief, Dermatology Branch, National Institutes of Health, speaks on cytokines involved in the pathophysiology in pustular psoriasis and off-label therapy use.

A nationwide study in Finland showed that the number of antibiotics and asthma drugs fell by 59.6% and 19.8%, respectively, from 2019 to 2020, generating millions in cost savings.

Researchers said they wanted to take a broad look at the level and scope of the disruption for those with Parkinson disease and dementia still living at home and compare the findings to before the pandemic.

Researchers have found that most US patent infringement cases against biosimilar manufacturers cover patents filed over a decade after the originator product's FDA approval, leading to limits on competition among biologic drugs.

Over the 24-year period, there were 57 spinal muscular atrophy diagnoses in 53 families, and a disease birth prevalence of 1 per 8286 births in Estonia.

Throughout their paper, researchers highlighted acne treatment for these patients often involves other considerations—including reproductive health and mental health—and dermatologists should keep these in mind when making decisions for each patient.

Given the heterogeneous nature of breast cancer, biomarkers evaluated throughout treatment help provide a clearer picture of the treatment paradigm.