Ron Do, PhD, associate professor, Charles Bronfman Institute for Personalized Medicine at Mount Sinai, and Iain Forrest, MD-PhD candidate in Dr Do’s lab, explain their study's implications for providers and how age plays a role in genetic variant penetrance.
Due to advances in the treatment of spinal muscular atrophy (SMA), the lifespan of patients with the disease has increased significantly, allowing them to enter adulthood. However, the change in SMA prognosis has also led to a knowledge gap in the natural history, management, and treatment strategy for adult patients, according to the researchers.
Quality of life for children with asthma may be influenced by psychological and sociocultural determinants of health.
A retrospective, quasi-experimental study found that patients admitted to the intensive care unit (ICU) for acute respiratory failure (ARF) saw better outcomes when an inter-ICU transfer came within the first 2 days of admittance.
In this new analysis, results showed that CCL3, CXCL8, CXCL9, and CXCL10 may be indicators of disease severity.
Glenn Balasky, executive director of Rocky Mountain Cancer Centers, previewed topics and potential takeaways from his discussion on building a community oncology practice for the future at the 2022 Community Oncology Conference.
This new study investigated cardiovascular disease (CVD) risk outcomes among patients with a serious mental illness (SMI) attending primary care clinics that were part of HealthPartners and Park Nicollet in Minnesota and Wisconsin.
Researchers found that low levels of vitamin D and the prevalence of peripheral neuropathy were common in patients with multiple myeloma, suggesting that addressing the former could help prevent the latter.
Administering dupilumab for other atopic conditions, including atopic dermatitis (AD) and asthma, in patients who also have eosinophilic esophagitis (EoE), resulted in improved EoE symptoms.
A recent study found that a selection of non-invasive markers could help identify high-risk children with pulmonary arterial hypertension associated with congenital heart disease.
Women are known to experience more adverse events with chemotherapy, but a recent study found an increased risk across therapy types, especially immunotherapy.
Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.
A new opinion indicates paying those with substance use disorder to stay clean could be legal; the 2020 Census undercounted some racial minorities; the true global COVID-19 death toll could be 3 times higher than the official tally.
Soumya Chakravarty, MD, PhD, FACP, FACR, strategic lead, Rheumatology Therapeutic Area at Janssen, spoke on adverse patient outcomes caused by diagnostic delays in psoriatic arthritis and progress made to address this unmet need.
Across these ethical considerations, the researchers emphasize the importance of collaborating with patients and their caregivers.
This new study of pediatric patients with type 1 diabetes from France and Belgium investigated the effectiveness of insulin delivery via closed-loop and open-loop systems.
David Penberthy, MD, MBA, medical director of radiation oncology at Southside Regional Medical Center, discusses his theme as president-elect of the Association of Community Cancer Centers (ACCC) and what initiatives and discussions he looks forward to addressing over the next year.
Worse cognitive performance was seen among children prior to migraine attack onset compared with those who never developed migraine.
A recent review found that patients with chronic kidney disease (CKD) have fewer daily steps than the recommended physical activity benchmark, which has implications for their CKD prognosis.
This new study evaluated the influence of transmission bottlenecks on HIV-1 infection virulence by comparing outcomes between penile-vaginal intercourse and anal intercourse, and found more severe disease among heterosexual individuals compared with men who have sex with men.
Reasons for pursuing genomic profiling among patients with advanced bladder, renal, and prostate cancers included guiding treatment and improving treatment response, in which age and education level were found to significantly influence shared decision-making.
The House passes a $1.5 trillion spending package that does away with pandemic relief and adds the Violence Against Women Act; Purdue awaits a judge’s approval for a $6 billion settlement for its opioid case; redlining laws led to 45 million Americans breathing dirtier air decades after they were removed.
People who have both severe mental illness (SMI) and obstructive airways disease (OAD) experience extraordinary disability and isolation, which leads to a lack of access to care and increased use of urgent care.
This new study focused on the patient perspective following a diagnosis of ductal carcinoma in situ (DCIS), a noninvasive type of breast cancer also referred to as stage 0 or pre-cancer, as well as their concerns over follow-up
After years, the biosimilars horizon may be here with valuable opportunities to improve patient outcomes and reduce costs, said Eric Palmer, president and CEO of Evernorth.
A recent study found that children with sleep-disordered breathing who live in areas with greater socioeconomic vulnerability are less likely to meet with an otolaryngologist after being referred by their primary care physician.
Researchers used data to develop a nomogram that identified factors associated with worse prognoses in patients with non–small cell lung cancer (NSCLC) and liver metastases.
Dupilumab was shown to significantly improve factors of skin barrier function, including transepidermal water loss, lipid composition, and filaggrin, among patients with moderate to severe atopic dermatitis.
The meta-analysis found insufficient evidence to assess the validity of the screening in diagnosing age-related macular degeneration.
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