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Results of a retrospective study conducted in China assessed the safety and efficacy of ixazomib for multiple myeloma.

A study examining the relation between rituximab infusion and hospitalization as a result of COVID-19 for patients with multiple sclerosis (MS) found that the 2 were not related, contradicting past research.

Clinicians should be willing to work with patients eager to try “do-it-yourself” insulin systems, but should also warn them of the risks, the guidelines state.

An FDA advisory panel voted in favor of emergency authorization for Merck's COVID-19 pill; South African drug maker Aspen Pharmacare announced that it was finalizing the first agreement to control production of the Johnson & Johnson COVID-19 vaccine in Africa; the International AIDS Society launched its latest strategy to find a cure for HIV.

Researchers sought to classify opioid and triptan use for migraine based on geographic location.

Results of a cohort study showed that transfeminine individuals may be at a higher risk for type 2 diabetes (T2D) compared with cisgender females, but revealed little evidence that gender-affirming hormone therapy impacts diabetes risk.

The social, structural, and economic drivers of HIV are not so different from COVID-19. Still, those who have witnessed the ravages of HIV have been in a 40-year holding pattern when it comes to a vaccine, according to experts from the Rutgers School of Public Health.

This new investigation into the use of sodium-glucose co-transporter 2 (SGLT2) inhibitors for heart failure shows significant benefit in persons with heart failure with preserved ejection fraction (HFpEF).

CTI BioPharma's New Drug Application had previously been granted Priority Review. The PDUFA date was November 30.

The CDC expands its recommendation on booster shots to all adults aged 18 and older amid Omicron variant concerns; a federal judge temporarily blocks COVID-19 vaccine mandates for health workers in 10 states; the Supreme Court will begin hearing arguments on Mississippi’s landmark abortion case tomorrow.

Using data from the FDA Adverse Event Reporting System, researchers investigated the prevalence of pentosan polysulfate sodium–associated retinal disorders.

Patients with concomitant psoriasis, nail psoriasis, and psoriatic arthritis (PsA) exhibited significant improvements in joint and disease severity symptoms, as well as quality of life (QOL) after 3 months of treatment with tumor necrosis factor-α (TNF) inhibitors of adalimumab, etanercept, or infliximab.

Data showed differences in statin use to prevent cardiovascular disease among Finnish patients with type 2 diabetes.

Dutch investigators found a screening questionnaire might be a good tool to identify patients warranting further testing for systemic lupus erythematosus (SLE).

Results of a nationwide retrospective cohort study show maternal infection with syphilis, gonorrhea, or chlamydia was associated with an increased risk of preterm birth.

President Joe Biden will provide an update today on his administration’s response to the Omicron COVID-19 variant; marked rise in lung transplants for patients with COVID-19 sparks ethical questions; an independent panel of experts will advise FDA tomorrow on the use of Merck’s COVID-19 antiviral pill.

A small study found a correlation between age and small vessel disease risk that suggest the importance of regular brain MRI monitoring in patients with Fabry.

Funmi Olopade, MD, FACP, professor of medicine and human genetics and founding director of the Center for Clinical Cancer Genetics and Global Health at the University of Chicago Medical Center, explains how transgender women are included in breast cancer research and emphasizes why it is important to include all women.

In a recent study, researchers detailed the use of various biosensors for minimal residual disease (MRD) detection in non–small cell lung cancer (NSCLC).

The prevalence of chronic obstructive pulmonary disease (COPD) underdiagnosis, false diagnosis, and treatment in the primary care setting is high and often inconsistent with Global Initiative for the Chronic Obstructive Lung Disease (GOLD) guidelines.

Kimberly Westrich, MA, vice president of health services research at the National Pharmaceutical Council, discusses the shift to a value-based system from a fee-for-service one and how the health care system can incentivize high-value care.

This new review from China investigated the relationship between diet and fertility among women with polycystic ovary syndrome (PCOS) and provides clinical and evidence-based nutrition recommendations to help manage their reproductive health.

Kidney organoids designed with the same mutation as that present in Fabry disease can help investigators better understand how the disease functions, authors suggested.

Results of a retrospective study revealed potential markers of COVID-19 severity among those with chronic obstructive pulmonary disease, asthma, or chronic bronchitis.

An open-label randomized trial found patients using the closed-loop system had more time in their target glucose ranges.

A recent review outlined advances and challenges in utilizing liquid biopsy to detect measures such as circulating tumor DNA in patients with solid tumors.

Further investigation on the pathogenesis and treatment of patients with schistosome-associated pulmonary arterial hypertension (Sch-PAH) may lead to improved symptoms and higher rates of survival.

Judith Lavrich, MD, and Jordan Hamburger discuss what additional studies need to be carried out in order to better understand the effects of virtual learning on children's long-term eye health.