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Obstructive sleep apnea was identified as an independent risk factor for severe coronavirus disease 2019 (COVID-19) resulting in hospitalization.

Compared with triptan nonresponders, patients with migraine who report a response to at least 1 triptan have a higher likelihood of responding to treatment with erenumab, according to real-world data published in The Journal of Headache and Pain.

Results of a phase 2 trial showed that an activin type II receptor blockade, achieved via bimagrumab, led to significant loss of fat mass, gain in lean mass, and metabolic improvements among patients with type 2 diabetes (T2D) and overweight or obesity.

Swedish patients with type 2 diabetes and obesity who underwent gastric bypass surgery exhibited a reduced risk of developing new diabetic retinopathy, compared with those who did not undergo surgery.

Vaccination rates against coronavirus disease 2019 (COVID-19) are significantly lower in Black Americans compared with White Americans; spotlighting the impact of the pandemic on children with mental illness; a rapid blood test predicts which patients with COVID-19 are at highest risk of severe complications or death.

Amid recent reforms on price transparency by CMS and the Trump administration, payers' workloads will substantially increase with notable challenges that include having to maintain accurate prices and the impact of exposed negotiated rates.

Investigators found that the ratio of lymphocytes to high-density lipoprotein (HDL) performed better in predicting pulmonary function than the neutrophil-lymphocyte ratio and the platelet-lymphocyte ratio.

The incoming Biden administration will be challenged to address flex capacity, the supply chain, and real-time data as we transition from coronavirus disease 2019 (COVID-19) response to durable recovery.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

A population-based study from the Netherlands showed that individuals with had at least 1 direct relative affected with chronic kidney disease (CKD), suggesting that biomarkers for CKD can aid in detecting the early stages of the disease.

A flow cytometric score developed in 2012, which uses 4 parameters to distinguish low-grade myelodysplastic syndromes (MDS) from nonclonal cytopenias, is simple and practical for screening patients with MDS, according to research published in the American Journal of Translational Research.

Tyrosine kinase inhibitor (TKI) therapy enables patients with chronic myeloid leukemia (CML) to reach life expectancies equivalent to the general population and treatment-free remission, but quality of life can deteriorate with treatment.

There is a greater prevalence of acid reflux disease in patients with both of these conditions, and treating the sleep apnea in turn may improve the acid reflux, which then may improve the cough, stated Krishna M. Sundar, MD, clinical professor, Pulmonary Division, Department of Medicine, and medical director, Sleep-Wake Center, University of Utah.

Machine learning identified patients with rheumatoid arthritis who may have an increased chance of achieving clinical response with sarilumab, with those selected also showing an inferior response to adalimumab.

CMS finalized a rule on electronic data entry that will streamline the prior authorization process and improve data transparency for providers, payers, and patients.

Florida Cancer Specialists has integrated SpaceOAR Hydrogel into its armamentarium as a pre-treatment for radiation therapy in prostate cancer patients.

New research underscores the substantial economic burden associated with early discontinuation of guideline-recommended hypomethylating agent (HMA) therapy among patients with refractory anemia with excess blasts, a diagnosis that substantially overlaps with higher-risk myelodysplastic syndrome (MDS).

Mepolizumab and benralizumab are both potent targets of the interlukin-5 pathway with the ability to significantly reduce eosinophil counts, according to new research published in Allergy, Asthma & Clinical Immunology.

Panel testing for genetic variants linked to more cancers is cost-effective than just testing or BRCA1/2 mutations, says a clinical director for a women's health company.

Based on US health insurance consumer behavior reported in the eHealth Insights: 2020 Retrospective report, notable trends of the past year to watch for in 2021 include the popularity of $0 premium Medicare Advantage plans, the rise of telemedicine, and potential hesitancy against taking a vaccine for coronavirus disease 2019.

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HHS aims to ease access to medication-assisted treatment for patients with opioid use disorder; David Kessler, MD, named top Operation Warp Speed official; President-Elect Joe Biden unveils coronavirus disease 2019 (COVID-19) relief package.

Focused ultrasound subthalamotomy was shown to improve motor features among patients with Parkinson disease who present with asymmetric symptom severity.

Investigators using real-world data found that patients receiving treatment from slow mist inhalers (SMIs) had fewer exacerbations and hospitals readmissions compared with patients using dry powder inhalers (DPIs).

The researchers say their new results can ease the concerns physicians or patients have when weighing the decision to switch route of administration for rheumatoid arthritis treatment.

The US Surgeon General, Vice Admiral Jerome Adams, MD, and other officials urged for greater uptake of FDA-approved treatments for coronavirus disease 2019 (COVID-19) in an effort to slow the surge of cases requiring hospitalization. However, logistic, monetary, and efficacy concerns may have drastically limited the amount of biologic treatments actually administered to patients.

Among the viewpoints offered by the authors to overcome barriers in solving unmet needs in pulmonary arterial hypertension (PAH) are preclinical pipelines for drug repurposing, working around challenges in early-stage trial design, and refining target selection and demonstration of engagement.

A comparison of 3 levels of SARS-CoV-2 antibodies in convalescent plasma shows that the 30-day death rate was lowest in the group receiving high-titer plasma.