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Dupilumab, with or without topical corticosteroids, significantly reduced pain and discomfort in patients with moderate to severe atopic dermatitis.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

For patients with polycythemia vera (PV), there are no differences in recommendations for preventing complications when using ruxolitinib than for myelofibrosis (MF).

A study looking at chronic obstructive pulmonary disease (COPD) and coronary heart disease found that inhaled corticosteroids (ICS) reduced future cardiac events in patients not known to have coronary heart disease.

Lowering the higher rates of diabetes seen among racial and ethnic minorities requires solutions to address all of the major factors that contribute to diabetes prevalence.

A multidisciplinary spine intervention can reduce chronic back pain–related health care utilization and costs, according to a study published in Spine.

A registry study suggests 4 in 5 patients with heart failure might benefit from the SGLT2 inhibitor dapagliflozin.

Patients with Parkinson disease (PD) who do not experience tremor were found to show improvements in reward learning after taking dopaminergic medication, while those with PD and tremor exhibited no benefit in reinforcement learning.

Findings from the GALACTIC-HF trial presented at AHA Scientific Sessions 2020 showed that patients with heart failure (HF) with reduced ejection fraction who took omecamtiv mecarbil showed a significant 8% relative risk reduction in a composite of a HF event or death from cardiovascular causes, compared with those taking placebo.

A look into the US cities hardest hit by cases of coronavirus disease 2019 (COVID-19); Anthony Fauci, MD, urges Americans to double down on health precautions amid COVID-19 surges; a study spotlights risk of high health care costs among the insured.

This week, the top managed care news included the Supreme Court signaling willingness to uphold the Affordable Care Act; Pfizer’s coronavirus disease 2019 vaccine shows 90% efficacy; racial disparities in lung cancer screenings and prescribing biologics.

Age, sex, and body mass index typically drive the development of obstructive sleep apnea, noted Krishna M. Sundar, MD, clinical professor, Pulmonary Division, Department of Medicine, medical director, Sleep-Wake Center, University of Utah.

Chimeric antigen receptor (CAR) T cells can be highly effective, but the durability of the therapy has been lacking in many patients with hematological malignancies. Many efforts are underway to fix this problem.

The FIDELIO-DKD program is perhaps just the beginning of seeing how finerenone can be used, said Rajiv Agarwal, MD, MS, FASN, a professor of medicine at Indiana University School of Medicine and a staff physician at the Veterans Affairs Medical Center in Indianapolis, Indiana.

Living in a neighborhood rife with violent crime and prostitution was linked in this recent study to worse virologic control among pregnant woman living with HIV.

A report by PwC discusses the health care agenda of President-elect Joe Biden, particularly how his term will shape the future of the Affordable Care Act, value-based care, and drug prices.

Researchers have identified additional mutations in both SMN1 and other genes, some of which may be associated with the onset of spinal muscular atrophy (SMA).

The Gates Foundation will add another $70 million of funding for vaccines and treatments against coronavirus disease 2019 (COVID-19); nursing homes see rising COVID-19 cases; finding health coverage for workers laid off due to the pandemic.

New research suggests it’s not disruptive to give radiation therapy to patients who are awaiting CAR T-cell therapy for relapsed or refractory multiple myeloma.

Michael S. Fitts, assistant dean for user access and diversity at the University of Alabama at Birmingham, discusses misconceptions of Parkinson disease related to race and age, as well as advice for patients in their treatment journey.

Experts spotlighted sex- and gender-specific changes in normal sleep and sleep disturbance, as well as attributable risk factors, during a session at the CHEST 2020 annual meeting.

Intravenous diuretic treatment of patients with decompensated heart failure can increase urine output, promote weight loss, and improve dyspnea.

Between 2003 and 2016, the United States saw a 4-fold increase in drug use–related endogenous endophthalmitis hospitalizations, contributing to a substantial health care use burden.

The US may have inadequate testing for coronavirus disease 2019 (COVID-19); potentially 80% of new COVID-19 cases are linked to indoor venues; protection against measles and mumps is suboptimal among cancer patients.

Treatment targets include several interleukins, immunoglobulin E, and alarmins, pointed out Nicola Hanania, MD, MS, pulmonary critical care physician and director, Airway Clinical Research Center, Baylor College of Medicine, Houston.

If you only experience migraine with your period for a few days, it would be difficult to recommend taking a drug all the time, said Stephen Silberstein, MD, professor of neurology at Thomas Jefferson University and director of the Headache Center at Jefferson Health.

In what is believed to be the first study of its kind, investigators found patients with leukemia face a higher risk of suicide than the general public, especially if they had acute myeloid leukemia.

Improvements in completed visits while using telemedicine to conduct rheumatology visits during the coronavirus disease 2019 pandemic may present an option for continued telemedicine use for follow-up care.