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This week, the top managed care news included top pharmaceutical executives refuse to attend a Trump meeting after executive orders on costs; a survey shows concerns about reopening schools, toll of COVID-19 split by party lines, background; a review of 20 years of data concludes vaccines are "remarkably safe."

The ADAURA trial was stopped in April 2020 after an independent monitoring committee called for the trial to be unblinded 2 years early based on a determination of overwhelming efficacy.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Occipital pain is linked to migraine, but the 2 conditions are sometimes difficult to separate.

Bristol Myers Squibb and bluebird bio submitted a second Biologics License Application (BLA) to the FDA for idecabtagene vicleucel (ide-cel), the companies’ investigational B-cell maturation antigen–directed chimeric antigen receptor (CAR) T-cell immunotherapy, indicated for adults with relapsed and refractory multiple myeloma (MM).

During the coronavirus disease 2019 (COVID-19) pandemic, clinics have closed to varying degrees. As clinics look to reopen or welcome back patients after a COVID-19 infection, the American College of Rheumatology (ACR) has released advice on strategies for reopening practices as the pandemic continues.

A study outlines the association between early school closures and reduced coronavirus disease 2019 (COVID-19) incidence and mortality; Baylor University will ship COVID-19 testing kits to all students expected to return to campus in the fall; the National Collaborative on Gun Violence awarded $7.5 million in grants to fund research on the crisis.

Patients with myeloproliferative neoplasms (MPNs) have high disease burden, and management of their disease can vary widely to include watchful waiting, phlebotomy, or drug therapy.

Results for EMPEROR-Reduced have been highly anticipated, as they are expected to set off a new round of competition in the drug class, which was first developed to treat type 2 diabetes.

Researchers discuss the implications of nonmotor symptoms in patients with Parkinson disease, which can contribute to major sleep, ocular, olfactory, throat, cardiovascular, gastrointestinal, genitourinary, or musculoskeletal disorders.

Although the name suggests the disease affects only the kidneys, development of fluid-filled cysts can spread to the liver, the pancreas, and other organs. While a healthy kidney is about the size of a fist, a kidney filled with cysts from polycystic kidney disease (PKD) can grow to be about the size of a football weigh up to 30 pounds

Less than 1% of all breast cancers occur in men, making this a rare disease among that patient population, and most treatment guidelines are based on outcomes and survival rates seen in women with the disease.

Insulin cost-sharing caps may benefit children and young adults with type 1 diabetes (T1D), according to new research published in JAMA Pediatrics.

Patients who have both skin and joint symptoms with psoriatic arthritis have greater disease burden and worse quality of life compared with patients who have joint-only involvement.

Results from a racially diverse clinical trial show that despite bringing palliative care to rural and minority populations with heart failure facing hurdles to accessing such care, using telehealth delivery methods to improve access does not improve the mood or quality of life of patients or their caregivers.

Using automated spectral-domain optical coherence tomography, researchers found the presence of subretinal fluid (SRF) in individuals with diabetic macular edema (DME) is associated with lower baseline best-corrected visual acuity. The findings of this retrospective study suggest automated quantification of intraretinal fluid and SRF may be an objective approach to assess DME treatment.

Through GoMo Health’s partnership with the Center for Health Technology and Innovation (CHTI) at the American Heart Association (AHA), GoMo, in collaboration with the AHA, has launched the telehealth care coordination solution, known as Concierge Care, a behaviorally-based, patient-centric care solution that can lead to measurable and sustainable population health, said Patrick Dunn, program director of CHTI at the AHA, and Bob Gold, chief executive officer of GoMo Health.

Laboratories cannot keep up with the demand for coronavirus disease 2019 (COVID-19) testing results; job losses in Texas have led to many losing their insurance; a new California poll shows that Latinos worry most about finances and getting sick from COVID-19.

Through the partnership, Humana and Heal will expand the startup’s current markets to include Chicago, Charlotte, Houston and others that are part of Bold Goal, a multi-year effort to improve overall health of communities by addressing both medical needs and working with partners to address social determinants of health, such as food insecurity.

FDA increased oversight of antibody testing on May 5, requiring them to meet standards of other molecular tests.

HIV-positive individuals with end-stage kidney disease may now have a larger pool of kidneys available to them, with recent study results from the National Institutes of Health (NIH) showing that kidneys from HIV-positive deceased donors can be used in addition to those from HIV-negative donors.

When it comes to ease of use, ability to self-inject, and confidence in using an erenumab-prefilled disposable autoinjector, individuals with migraine consistently endorsed the preventive treatment, according to study results published in Patient Preference and Adherence.

Amid the coronavirus disease 2019 pandemic in Italy, a significant number of patients with epilepsy reported difficulties managing their condition, especially those who reported greater use of antiseizure medications for chronic therapy and poor sleep quality, according to study findings.

The race for a coronavirus disease 2019 (COVID-19) vaccine is one of the most urgent public health challenges, with multiple vaccine candidates entering phase 3 trials and case counts around the world steadily climbing. MJH Life Sciences™ will host a free webinar with the top minds in infectious disease, virology, and vaccinology to discuss the latest trial information on vaccines.

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are associated with an almost 3-fold increased risk of diabetic ketoacidosis (DKA) in some patients with type 2 diabetes (T2D), according to data from a retrospective cohort study published in Annals of Internal Medicine.

Compared with digital mammography, digital breast tomosynthesis, also called 3-dimensional (3-D) mammography, has been proven superior at effectively detecting breast cancer and leading to fewer recall visits, but more information is needed for how subgroups of women with different breast densities benefit from the screening method, especially those classified as having extremely dense breast tissue.

Data from DAPA-CKD show that the trial met all its primary and secondary end points for patients with chronic kidney disease, with and without type 2 diabetes. The announcement comes after a data monitoring committee halted the trial in March 2020 when it found the evidence of efficacy was overwhelming.

A meeting at the White House with top pharmaceutical executives has been cancelled after the Trump administration’s executive orders signed this past Friday on the topic drew criticism from the drug industry; Kodak has won a $765 million US government loan to assist in expediting domestic production of drugs to treat several medical conditions and reduce US reliance on foreign supplies; more than a third of patients with mild illness from coronavirus disease 2019 (COVID-19) reported related symptoms that lasted for 2 to 3 weeks after testing positive.