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A combination of machine learning and random optimization may aid in predicting medication overuse in migraineurs, if clinical/biochemical features, drug exposure, and lifestyle are taken into consideration, according to a study published in Computational and Structural Biotechnology Journal.

Early trial results on a possible coronavirus disease 2019 (COVID-19) vaccine seem promising; out-of-state visitors cannot enter Hawaii until September because of COVID-19; could Arkansas soon see Medicaid work requirements again?

Pralsetinib, an investigational precision therapy in late-stage development for individuals with alterations in the RET gene, would be jointly sold in the United States by the 2 companies if it is approved.

Subclinical changes in retinochoroidal vasculature occur in obese individuals, according to a study published in PLoS ONE. Surgical intervention, such as bariatric surgery, may have a favorable outcome on the choroidal thickness in these patients’ eyes.

Using mindfulness meditation apps may provide an effective way to self-manage and reduce depression and anxiety in patients with myeloproliferative neoplasm (MPNs).

States currently facing a surge of coronavirus disease 2019 (COVID-19) cases also report the greatest increases in residents who lost health insurance due to the pandemic, according to an analysis published by Families USA.

Breast cancer diagnosed in the year following a negative result after a mammogram has now been associated with an increase in mortality compared with breast cancer detected at a screening, report JAMA Network Open study results.

A quality improvement project led by a multidisciplinary team was found to significantly improve on-time administration of levodopa and other medications for patients with Parkinson disease, according to study findings.

There was a greater incidence of heart disease, both cardiovascular and ischemic, among women and men who survived childhood maltreatment, according to study results published Monday from the United Kingdom.

In individuals with type 2 diabetes (T2D), sleep problems are associated with disturbances in cortisol responses to stress, in addition to changes in diurnal cortisol output, according to a study published in Psychoneuroendocrinology.

A pair of late-breaking abstracts presented during AIDS 2020, this year’s virtual meeting of the International AIDS Society, detailed the effects that the coronavirus disease 2019 pandemic has had on trends in at-risk sexual behaviors and pre-exposure prophylaxis (PrEP) use, both in the United States and in Australia, due to shelter-in-place orders and social distancing.

Florida announced a record-breaking 15,000 new coronavirus disease 2019 (COVID-19) infections on Sunday; New York City marks its first day without a COVID-19 death since the pandemic began; Education Secretary Betsy DeVos defended the reopening of schools in the fall.

Researchers called for new guidance to address the underreporting of patient engagement in rare disease clinical trials after finding a dismal amount of patient-reported outcome measures listed in orphan drug labeling claims.

Two abstracts presented at the European Hematology Association's annual meeting evaluated the frequency of myeloid malignancies in patients with autoimmune disease and the impact autoimmune diseases have on patients with sickle cell disease.

Clinical trial result revealed that upadacitinib may be more effective in treating patients with rheumatoid arthritis than the gold standard of care, methotrexate.

A new oral therapy approved by the FDA will provide patients with myelodysplastic syndromes, who typically visit a health care facility for intravenous treatment, with an oral at-home option that can be beneficial during the coronavirus pandemic.

New research sheds light on how multiple sclerosis affects the work lives of people with the disease. The data show that these patients face higher risks of missed work, even for reasons not directly linked to the disease.

Palliative medicine consultations for heart failure were linked with increased rates of advance directives being included in a patient’s electronic medical record, according to study results published this month in Journal of Maine Medical Center.

A new analysis of bone marrow plasma cells has helped to identify two biomarkers for multiple myeloma, which appear to play a role in the prognosis and clinical characteristics of the disease.

The focus on curbing COPD prevalence has largely focused on smoking cessation, but there are other factors, including diet, that can contribute to the risk of developing COPD.

The coronavirus disease 2019 pandemic presents a new challenge: patients have severe flu-like symptoms, but the virus can also cause renal failure. Doctors and patients need analgesics that go easy on the liver and kidneys but are not addictive, and this week researchers at LSU Health New Orleans Neuroscience Center of Excellence announced they have discovered a new class of drugs that can do the job.

This week, the top managed care news included CMS planning to pay more for at-home dialysis equipment; ACR supports continued use of telemedicine after the COVID-19 pandemic passes; AJMC®’s coverage of AIDS 2020, the 23rd International AIDS Conference.

Scientists do not yet have a full understanding of how multiple myeloma develops, but a new article suggests the gut microbiome is one factor that may play a role.

In patients with Parkinson disease (PD) who underwent deep brain stimulation, dementia prevalence and incidence were not found to be higher than those in the general PD population, according to study findings.

A new study suggests that people living with multiple sclerosis (MS) are often concerned about the costs of their care, but they do not always raise the concern with their doctor.

Investigators used death certificate data to determine the annual average decline of deaths attributed to systemic sclerosis.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.