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Exacerbation of air pollution and heat exposure related to climate change are significantly associated with serious adverse pregnancy outcomes in the United States, results from a systematic review published in JAMA Network Open show. In response to increasing levels of ozone and particle pollution, 17 attorneys general this week called on the Trump administration to strengthen standards regulating particulate matter pollution.

A Taiwanese study revealed that attributes associated with polycystic ovary syndrome (PCOS) may increase the risks of those patients developing psoriasis as well.

Voters in Oklahoma will decide whether or not to amend the state's constitution to expand Medicaid; new studies find that nearly 300 children in the United States have contracted a rare inflammatory disorder related to coronavirus disease 2019 (COVID-19); the House of Representatives passed a bill aimed to bolster the Affordable Care Act.

Patients with steroid refractory acute graft-versus-host-disease (GVHD) have a better overall response rate (ORR) when treated with ruxolitinib compared with the best available therapy, according to results from a phase 3 trial presented at the European Hematology Association’s annual meeting.

The decision comes almost exactly a month after results from KEYNOTE-177 were presented at the annual meeting of the American Society of Clinical Oncology.

A study analyzing patients with psoriasis revealed that personality traits may have a greater impact on the development of social anxiety than disease severity.

Metformin-based therapy may be an optimal first-line treatment for patients with type 2 diabetes (T2D) and low cardiovascular risk, according to a systematic review and network meta-analysis published in Annals of Internal Medicine.

The FDA approved Phesgo (pertuzumab/trastuzumab/hyaluronidase-zzxf) as a subcutaneous (SC) treatment for adult patients with metastatic human epidermal growth factor receptor 2 (HER2)-positive breast cancer or early-stage HER-2 positive disease. The treatment combines 2 monoclonal antibodies in a single SC injection.

Both frontline and nonfrontline health care workers were found to experience stark levels of stress and poor sleep quality amid the coronavirus disease 2019 (COVID-19) pandemic, with being female and having a professional background indicated as predictors of these effects, according to study findings.

Being on an antiretroviral treatment (ART) regimen of tenofovir disoproxil fumarate/emtricitabine may lower the risk of HIV-positive individuals contracting coronavirus disease 2019 (COVID-19).

Aging and longer axial length are independent and significant risk factors for myopic maculopathy, according to a study published in JAMA Ophthalmology. The study also found the condition, which is the leading cause of irreversible visual impairment and blindness for middle-aged and older individuals, has a much higher prevalence rate in Japan compared with other Asian countries.

Female migraineurs tend to exhibit longer attack duration and greater frequency of nausea, vomiting, osmophobia, and vertigo/dizziness, compared with male migraineurs, according to a community-based study.

Lockdown because of coronavirus disease 2019 (COVID-19) is not an option in impoverished and war-torn countries; the FDA grants emergency use clearance to Danaher Corp's COVID-19 antibody test; strategizing amid misinformation spread on the pandemic.

Rita E. Numerof, PhD, is the president of Numerof & Associates, a firm that helps businesses across the healthcare sector define and implement strategies for winning in dynamic markets. For more than 25 years, she has helped executives understand the implications of an evolving healthcare market. Working with leaders in the healthcare space, she has consulted with everyone from top academic and community hospital systems, payers, and Fortune 500 pharmaceutical, device, and diagnostics companies. She is the coauthor of several books, most recently, "Bringing Value to Healthcare: Practical Steps for Getting to a Market-Based Model" (2016).

These findings highlighted that adherence to drugs is not the sole issue to address in patients with comorbidities also serving as vital factors in designing managed care plans.

While cognitive functions in patients with Parkinson disease were only slightly impacted by the coronavirus disease 2019, notable effects on urinary issues and fatigue may warrant adjustments to therapy, according to study findings.

Patients with B-cell non-Hodgkin lymphomas and B-cell acute lymphoblastic leukemia can benefit greatly from chimeric antigen receptor (CAR) T-cell therapy, but providing that therapy has become much more difficult in the age of coronavirus disease 2019 (COVID-19).

Patients between the ages of 18 and 39 who are diagnosed with solid-tumor cancers are more likely than the general population to have germline mutations that could make them more susceptible to secondary primary cancers, according to new research.

Having lower socioeconomic status, comorbidities, or being covered by Medicare was associated with less receipt of immunotherapy for stage III melanoma.

In its first briefing in 2 months, the White House Coronavirus Task Force addressed rising cases of coronavirus 2019 (COVID-19) and positive test rates across states in the South, as well as the new data that show the majority of new cases are occurring in younger Americans.

While biologics may have improved outcomes in rheumatoid arthritis (RA), they also have higher costs and adverse events, and patients are more likely to request dose reductions or drug holidays.

The use of disease-modifying therapy (DMT) was associated with a lower risk of hospitalization for patients with coronavirus disease 2019 (COVID-19), and neurological disability, age, and obesity were independent risk factors for more severe cases of infection for patients with multiple sclerosis (MS).

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

There are thousands of rare diseases, but they each affect so few patients that diagnosis and treatment can be delayed by years. Researchers examined how machine learning has been studied in rare diseases and identified areas of opportunity where future studies can improve care and treatment of rare diseases.

This week, the top managed care news included CMS proposing rules for value-based contracting in Medicaid; claims data highlighting racial disparities in COVID-19 effects; an interview with Anthony Fauci, MD, on the progress made against HIV.

The CDC has updated its guidance as to who is at risk for more severe cases of coronavirus disease 2019 (COVID-19); Texas suspended its economic reopening in the wake of surging COVID-19 cases; HHS releases updated organ donation rules.

Minimal residual disease (MRD) status has been shown to be a better indicator of the prognosis of a patient with multiple myeloma (MM) than “complete remission.” Yet, it’s still not widely used in the clinic. A new article examines the problem.