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A recent review explored the mechanism of a 5-hydroxytryptamine (5-HT 1f) agonist used in the treatment of acute migraine pain.

While minimal residual disease has become an important way to track how patients respond to therapies for multiple myeloma, the treatment implications of the metric are not yet clear, according to a review article.

A new analysis of nearly 3 decades of data suggests leukemia rates are falling, except for 2 specific types.

The designation would be to reduce the risk of heart failure or cardiovascular death in patients who have suffered an acute MI, which is a known cause of heart failure.

Patients with Parkinson disease who experience visual impairment were found to be more prone to behavioral issues such as depression and anxiety, as well as dementia and death, according to study findings.

Because male breast cancer is such a rare disease, few strides have been made that convey advantages in its detection, incidence, and mortality. Most treatment guidelines have been extracted from studies performed among female patients.

Hemophilia care principles have been on the rise in Europe over the course of the last decade, however, differing regions and policies on the continent reveal gaps in access to various treatments and specialty services.

Automatic positive airway pressure was found to significantly improve peak oxygen uptake, left ventricular function, and quality of life in patients with comorbid obstructive sleep apnea and heart failure with reduced left ventricular ejection fraction, according to study findings.

Using composite endpoints to predict clinically important deterioration in chronic obstructive pulmonary disease (COPD) could help investigators assess disease activity in clinical trials and better manage individual patients, according to a recent study.

Karen Kobelski is the vice president and general manager of clinical surveillance, compliance & data solutions at Wolters Kluwer. She brings more than 25 years of experience to her position, which expands her previous leadership role over the Safety & Surveillance group to also include the Health Language portfolio of data normalization solutions.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Promoting engagement in physical activity in early rheumatoid arthritis (RA) can provide small benefits, according to results from a proof of concept study published in Musculoskeletal Care.

Transient ischemic attack is a common form of stroke, and 1 in 4 stroke survivors go on to experience a second stroke—most within the first month.

This week, the top managed care news included states facing COVID-19 spikes reporting health coverage losses; new COVID-19 data protocol raises concerns; and experts discuss key steps to reduce racial inequities in cancer care.

The review article highlights the many ways that multiple sclerosis (MS) affects women over the lifespan, from pregnancy to childbirth to menopause and beyond—and how both research and clinical practice fall short in meeting their needs.

Facedown positioning following surgery is not more likely to close large (≥400 mcm) macular holes compared with seating faced forward, according to a study published in JAMA Ophthalmology. However, visual acuity outcomes may be superior when patients are placed facedown after surgery.

Stress cardiomyopathy has presented in more patients with acute coronary syndrome during the coronavirus disease 2019 pandemic, despite none having positive antibody results for the virus, compared with several measured periods before the pandemic.

Research identified a new type of cell that is in the blood during the period before a rheumatoid arthritis flare and may be used to predict a flare in the weeks before one occurs, according to research published in New England Journal of Medicine.

The direct effect of childhood trauma on migraine is outweighed by the mediation effect of adulthood attachment, according to a study published in the International Journal of Environmental Research and Public Health.

Patients with type 2 diabetes who sleep too much (≥ 10 hours) or too little (≤ 5 hours) were found to exhibit a higher mortality rate. Those at a younger age of diabetes onset who reported longer sleep duration were also associated with greater risks of all-cause and cardiovascular mortality, according to study findings published today.

The authors said the results show a need to develop more targeted interventions for populations at risk of chronic kidney disease (CKD).

Opioid overdose deaths rose to a new record in 2019 after dropping in 2018; CMS Administrator Seema Verma was investigated for mishandling taxpayer dollars; a new report shows the many risks seniors face if children return to school.

Other respiratory diseases, such as chronic obstructive pulmonary disease and asthma, also have seasonal variations, but the impact of such variation on interstitial lung disease (ILD) is poorly understood.

Although early diagnosis of axial spondyloarthritis is crucial for patients to receive timely access to care and effective treatment, these patients experience a diagnostic delay of more than 7 years, on average.

To effectively end the HIV epidemic in the United States, combination strategies should be tailored according to need, backed by evidence-based interventions, and scaled according to location, report study results in The Lancet HIV.

Following an announcement that hospitals are to bypass the CDC and send all coronavirus disease 2019 (COVID-19)–related information to a central database, questions have been raised as to the future of COVID-19 data transparency and politicization.

Recognizing trends in health care that align with the COVID-19 pandemic and related racial disparities can improve the design of timely and effective strategies by employers to safely return employees to the workplace. Some of these efforts include less wait time for testing results, an improved focus on social determinants of health, and greater accessibility to care, said Lauren Vela, MBA, senior director at Pacific Business Group on Health.

A combination of machine learning and random optimization may aid in predicting medication overuse in migraineurs, if clinical/biochemical features, drug exposure, and lifestyle are taken into consideration, according to a study published in Computational and Structural Biotechnology Journal.