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Current guidelines for chronic obstructive pulmonary disease (COPD) call for using antibiotics in the emergency department (ED) when presented with acute exacerbations of COPD (AECOPD). A recent study sought to determine the rate at which patients with AECOPD are treated with antibiotics and also looked at the proportions of antibiotic classes prescribed, trends of antibiotic treatment, and identified independent predictors of antibiotic therapy.

Contributors to AJMC.com share their expertise about important, timely topics in managed care on a regular basis, and in 2018, these were the top 5 most-read articles they wrote and published on our online managed care network.

The practices that have been participating in CMS’ Oncology Care Model have undergone significant practice transformation in order to be successful in the program. However, even after being in the model for 2 years, there are still remaining opportunities for investment.

Hepatitis C virus (HCV) is the most frequently reported bloodborne infection in the United States, and prevalence has increased in recent years. Researchers recently sought to estimate the prevalence of HCV at the state level in order to more accurately guide prevention and care efforts.

This week, the top managed care news included a federal judge ruling that the Affordable Care Act is unconstitutional; new diabetes standards address cardiovascular risk; efforts targeting loneliness show improved health outcomes.

Researchers found no evidence that initiation of inhaled corticosteroids or leukotriene receptor antagonist therapy is associated with fewer wheezing/asthma attacks than therapy with a short-acting ß-agonist alone in preschool children with recurrent wheezing/asthma.

Outgoing Senator Orrin Hatch, R-Utah, is urging fellow Republicans to oppose President Donald Trump’s International Pricing Index; after 12 patients became seriously ill from stem cell injections, the FDA issued a warning to the company that made the product and sent a letter to 20 clinics warning them that stem cell products should be regulated by the agency; Cigna has finalized its $54 billion purchase of Express Scripts.

The year 2018 was a banner year for biosimilars, with the number of FDA-approved biosimilar products nearly doubling, and with major policy, business, and regulatory developments that moved the biosimilars marketplace forward. Here are 5 of the top developments in biosimilars for the past year, as reported by The Center for Biosimilars®, a sister site of The American Journal of Managed Care®.

The FDA has issued a warning that rare but serious cases of stroke and tears in the lining of arteries in the head and neck have occurred in patients with multiple sclerosis (MS) who received treatment with alemtuzumab (Lemtrada).

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