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The study illuminates how the weight loss, reduction in fatty liver disease, and a decreased risk for cardiovascular disease happens in patients taking SGLT2 inhibitors.

Earlier this week, the FDA granted priority review to a new drug application for fedratinib for the treatment of myelofibrosis. The drug had previously been awarded an orphan drug designation for the treatment of primary and secondary myelofibrosis.

This is part 1 of a 3-part vaccine series covering the potential of vaccines for infectious diseases, the impact of the antivaccination movement, and the promise of vaccines for cancer treatment.

Even moderate drinkers, who consume 7 to 13 alcoholic beverages per week, are at risk for developing high blood pressure, which can lead to heart attack or stoke, according to an abstract to be presented at the upcoming American College of Cardiology Scientific Sessions and Exposition in New Orleans, Louisiana.

Not having enough tissue is often a problem in precision medicine. The senior author of a new study said a liquid biopsy could become a new standard.

Patients with migraine headaches may have a risk of also having dry eye disease (DED).

Planned Parenthood and the American Medical Association have become the latest groups to sue the Trump administration over rule changes to Title X; an Ohio teen testified before a Senate committee about why he defied his mom and get vaccinated; and a federal judge has ruled that a unit of UnitedHealth Group had implemented policies discriminating against patients with mental health and substance abuse disorders.

Those who use e-cigarettes face higher risks of having a heart attack, experiencing emotional distress, and developing coronary artery disease compared to non-users, according to an abstract to be presented at the upcoming American College of Cardiology Scientific Sessions and Exposition in New Orleans, Louisiana.

The FDA is anticipated to release a finalized guidance document any day now around the regulation of fecal microbiota transplants for the treatment of Clostridium difficile infection. The outcome will dictate how they’re priced, who oversees their use, and who can make money off the treatment.

Analysis of a 2-year study showed that fluctuations in yearly chronic obstructive pulmonary disease (COPD) exacerbation rates may be associated with variations in Haemophilus influenzae colonization.

The FDA has approved esketamine for adult patients with treatment-resistant depression. The treatment has demonstrated improvement in depression symptoms, as well as sustained improvement in symptoms.

The Trump administration is working on a payment model that would favor home dialysis over in-clinic treatment for kidney disease; California is suing the Trump administration over rule changes to Title X; Trump has ordered the creation of a task force to address veteran suicide.

An analysis of exchange premiums finds that older adults with incomes just above the premium subsidy cutoff (400% of poverty), particularly in rural areas where premiums are highest, have the most severe affordability challenges.

Compared with other drug regimens, a carfilzomib-based regimen resulted in longer time to next treatment, as well as longer overall survival and improved 24-month survival, among patients with relapsed or refractory multiple myeloma (RRMM).

FDA Commissioner Scott Gottlieb, MD, will resign his post in about a month. The physician has been active in fighting youth e-cigarette use, encouraging generic drug competition, and in modernizing approval processes while leading the FDA. Reports said he wants to spend more time with his family.

A second patient has been reported to have been cured of infection with HIV since the start of the epidemic; thousands have reported complications to the FDA with medical devices and implants; a 30-person national ethics committee has been appointed in China to oversee high-risk clinical trials.

Researchers discovered a strong correlation between cerebral small vessel diseases and motor symptoms in patients with Parkinson disease, according to a recent cross-sectional study.

The results come after the American Diabetes Association and the American College of Cardiology have recently issued guidelines calling for the use of GLP-1 receptor agonists for patients with type 2 diabetes and cardiovascular risk.

Another study dispelling concerns about links between the measles, mumps, rubella (MMR) vaccine to autism has been released, this time with additional focus about subgroups of children.

Two abstracts presented at the Transplantation and Cellular Therapy Meetings analyzed the detection of minimal residual disease during and after hematopoietic stem cell transplantation.

The change comes on the heels of hearings in Congress where insulin costs were held up for scrutiny.

Some patient advocacy groups opposing Medicare changes have received funding from pharma companies in the past; new techniques allow scientists to target individual cells for analysis; rural nursing homes continue to close.

Low-value care that offers no benefit to patients, or can actually cause more harm than good, is costly to patients and the healthcare system. While low-value services are being identified and measured, it has been more difficult to reduce the use of low-value care.

According to recently published research, vitamins B12 and B9 can lower levels of homocysteine, improve anemia status, and boost physical health in patients with relapsing remitting multiple sclerosis (MS).

A recent study measured exhaled breath condensate (EBC) content that contained ultrafine particles (UFP) as a reflection of inflammation and oxidative stress in patients with chronic obstructive pulmonary disease (COPD) and as a marker of exacerbations.

In a recent study, researchers looked to analyze the association of migraine that presents with visual aura with atrial fibrillation (AF) as migraines with a visual aura are associated with a cardioembolic stroke risk.

A technology update, a new drug approval, and a drug recall due to more impurities.

The Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion that an orphan drug, volanesorsen (Waylivra), receive a conditional marketing authorization. The drug would be the first medication approved for the treatment of the familial chylomicronemia syndrome (FCS).