May 8th 2025
A study reveals higher health care costs and resource use for uncomplicated urinary tract infections (uUTIs), emphasizing the need for improved patient management strategies.
Dose Adjustment Considerations in Patients With Chronic Kidney Disease: Dr Linda Awdishu
November 3rd 2023For patients with chronic kidney disease, dose adjustments for other medications requires coordination with other specialists to maintain treatment efficacy, explained Linda Awdishu, PharmD, FASN, professor and division head of clinical pharmacy at the University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences.
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Presenters Have Hope for the Future of Trial Design in Pediatric Chronic Kidney Disease
November 3rd 2023Presenters at the American Society of Nephrology's Kidney Week 2023 discussed the past, present, and future of pediatric chronic kidney disease, as well as explored the obstacles and solutions for effective trial designs.
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Despite Risk, Patients With SCD Hopeful About Gene Therapies
November 2nd 2023Sickle cell disease (SCD) has known complications that include organ damage and failure, rhabdomyolysis, glaucoma, splenic sequestration, and vaso-occlusive crises. At present, the only potential cure is a bone marrow transplant, but it can be difficult to find a donor and there is a high rejection risk.
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CAR T-Cell Therapy Responses Differ by Race and Ethnicity, Study Finds
November 2nd 2023While response and safety may vary across racial and ethnic subgroups, progression-free survival and overall survival does not appear to differ when chimeric antigen receptor T-cell therapy is used in the treatment of patients with multiple myeloma.
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Glucose Fluctuation Linked to Slowed Nerve Conduction Velocity in Youth With T1D
November 2nd 2023High glucose variability in children and young adults with type 1 diabetes (T1D) strongly predicted slowed nerve conduction velocity, a forerunner of diabetic peripheral neuropathy, in a recent study.
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Private Maternal Insurance Coverage Associated With Lower Infant Mortality vs Medicaid
October 31st 2023Insurance status is known to be associated with health care access and outcomes, and a recent study found that maternal private insurance is associated with a lower infant mortality rate compared with public Medicaid insurance in the United States.
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SPHERE Registry Data Highlight Racial, Ethnic Disparities in PAH Treatment, Outcomes
October 31st 2023Data from the SPHERE registry revealed racial and ethnic discrepancies in disease severity, comorbidities, and outcomes experienced by patients with pulmonary arterial hypertension (PAH) receiving selexipag.
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Study Identifies Mechanisms of Resistance to Immunotherapy for Multiple Myeloma
October 30th 2023Investigators found that myeloma cells may lose or change targets and subsequently go undetected by these therapies, suggesting that screening for such changes regularly could help guide treatment.
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ASN Kidney Week Returns to Philadelphia to Highlight Latest Innovations, Issues in Renal Care
October 30th 2023The American Society of Nephrology (ASN) Kidney Week 2023 will take place in Philadelphia, Pennsylvania, from November 2-5, as experts from across the globe gather to discuss the latest innovations in renal care and current issues facing the field.
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STELLAR, SOTERIA Data Provide Insight Into Effects of Sotatercept in Pulmonary Arterial Hypertension
October 28th 2023At ERS International Congress 2023, new data related to use of sotatercept offered providers additional insight into the effects of the agent in people with pulmonary arterial hypertension (PAH).
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Ixazomib Shows Efficacy, Tolerability in Real-World R/R Multiple Myeloma Treatment
October 28th 2023A study of patients with relapsed or refractory (R/R) multiple myeloma who received ixazomib-based therapy in real-world settings found the treatment effective and tolerable in clinical practice.
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ANNEXA-I: Andexanet Alfa Shows Efficacy, Safety for Factor Xa Reversal in Acute ICH
October 27th 2023The phase 4 ANNEXA-I trial was stopped early after showing superior hemostatic efficacy and the capability to limit potentially life-threatening intracerebral hemorrhage (ICH) compared with usual care in patients taking oral factor Xa (FXa) inhibitors.
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Dr Melissa Levine on Implementing Value-Based Care in the Primary Care Setting
October 26th 2023Melissa Levine, MD, a family medicine specialist at Arizona Community Physicians and medical director for the Abacus Health accountable care organization (ACO), discussed strategies for succeeding in an ACO and how primary care can complement oncology care for patients with cancer.
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Exon-Skipping Therapy for DMD Linked to High Care Costs, Health Care Resource Utilization
October 25th 2023This comprehensive comparative analysis examined the economic and health care resource utilization implications of initiating glucocorticoid and exon-skipping therapy for Duchenne muscular dystrophy (DMD).
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GALACTIC Trial Reveals Less Successful RAAS Inhibitor Uptitration in Women Than Men
October 24th 2023Uptitration of renin-angiotensin-aldosterone system (RAAS) inhibitors was less successful in women than men with acute heart failure (AHF), especially in those with HF with reduced ejection fraction.
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