Opinion|Videos|October 29, 2025

Translating Real-World Outcomes in mCRC Into Patient Conversations

Panelists discuss how real-world outcomes inform patient conversations and support shared decision-making for third-line metastatic colorectal cancer therapies.

Panelists highlight how real-world outcomes shape patient discussions, especially when setting realistic expectations about efficacy, safety, and quality of life with third-line options.

They note that real-world evidence with trifluridine/tipiracil plus bevacizumab and with fruquintinib confirms trial findings, providing confidence to patients about likely benefits.

By framing treatment conversations around both clinical data and real-world outcomes, clinicians can foster shared decision-making that aligns patient goals with available therapies.

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