Hemophilia

Latest News

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FDA Approves Fitusiran for Reducing Bleeds in Patients With Hemophilia A/B

March 28th 2025

Data from the ATLAS research comprises a series of trials that have yielded years of long-term, comprehensive data on the safety and efficacy of fitusiran (Qfitlia; Sanofi).

Red blood drop with double helix | Image credit: Елена Бутусова-stock.adobe.com
Hemophilia A Gene Therapy Superior to Standard of Care in Phase 3 Trial

July 26th 2024

hemophilia damage | Image Credit: Akarat Phasura-stock.adobe.com
Field Study Highlights Differences in Factor IX Variant Lab Results

June 28th 2024

Hemophilia definition | Image Credit: © VitezslavVylicil - stock.adobe.com
In Patients With Hemophilia A, Physical Activity Levels Low

June 26th 2024

Red blood drop with double helix | Image credit: Елена Бутусова - stock.adobe.com
AAV5 Gene Therapy for Severe Hemophilia A Successfully Enables FVIII Production

June 20th 2024

Continuing Medical Education
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May 1st 2025

Addressing the Gaps and Clinical Challenges in Chronic Lymphocytic Leukemia: Updates and Strategies for Managed Care

1.5 Credits / Hematology, Hematologic Cancer, Oncology
May 1st 2025

Keeping Pace With New Developments in Multiple Myeloma: Updates and Strategies to Optimize Bispecific Antibodies and CAR T-Cell Therapy

1.5 Credits / Oncology, Hematology, Hematologic Cancer
May 1st 2025

ASH Annual Meeting Coverage: Highlighting the Recent Updates in TKI Use in the Treatment of CML – Insights and Application for Managed Care

1.0 Credit / Oncology, Hematology, Hematologic Cancer

More News

National Hemophilia Foundation Updates Name to National Bleeding Disorders Foundation
August 18th 2023

National Hemophilia Foundation Updates Name to National Bleeding Disorders Foundation

AJMC Staff
A 75-year-old foundation updates its name to reflect a more comprehensive mission.
Asian doctor checking on African baby boy in mother's arms. Healthcare for baby concept: © Dollydoll - stock.adobe.com
May 8th 2023

There Is Much to Consider and Discuss in Previously Untreated Hemophilia

Jared Kaltwasser
Treatment options have improved care, but also increased the need for patient education.
Blood sample positive with hemophilia disease: © jarun011 - stock.adobe.com
May 5th 2023

Bleeding, Damage Common in Pediatric Hemophilia Despite Prophylaxis

Jared Kaltwasser
About a quarter of joints examined had at least 1 joint bleed.
Service Satisfaction Indicator: © Olivier Le Moal - stock.adobe.com
May 1st 2023

Dutch Hemophilia Patients Report Satisfaction With Care

Jared Kaltwasser
However, the patients also said they worried about insufficient care coordination between specialists and other care providers.
picture of tubes of blood labels with the word hemeophilia
April 25th 2023

New Recombinant Factor IX Leads to Significant Cost Savings in Hemophilia B

Jared Kaltwasser
The projected cost reductions held both for patients switching from a different extended-half-life product and for patients switching from a standard-half-life product.
Medical Team Performing Surgical Operation in Modern Operating Room: © Gorodenkoff - stock.adobe.com
April 21st 2023

Patients With Bleeding Disorders Face Similar Surgery Risks to Healthy Controls

Gianna Melillo
Little is known about the risk of bleeding in patients with bleeding disorders who undergo major surgeries or outcomes for those managed perioperatively at hemophilia treatment centers.
Back view of strong motivated woman celebrating workout goals towards the sun. Morning healthy training success: © Dirima - stock.adobe.com
April 14th 2023

Certain Exercises Well Tolerated by Patients With Severe Hemophilia

Gianna Melillo
Recommendations are lacking on strength exercise intensity, tolerability, and adverse effects for patients with severe forms of hemophilia.
Hands holding a drop of blood, blood donation, blood transfusion, world blood donor day, world hemophilia day concept: © Rodrigo Rivas - stock.adobe.com
April 11th 2023

Many Patients With Hemophilia Experience Functional Declines Over Time

Gianna Melillo
Study authors determined that regular musculoskeletal assessments can help facilitate personalized care for patients who have hemophilia, in that they can detect changes early.
Ankle twist sprain accident in sport exercise running jogging: © mansong - stock.adobe.com
March 30th 2023

Pain May Predict Impaired Outcomes in Patients With Hemophilia and Ankle Hemarthropathy

Jaime Rosenberg
Hemarthropathy in multiple joints is a common feature of more severe forms of hemophilia, with the ankle joint often being reported as the main site of pain.
Doctor working with tablet in hands in the lab with message hemophilia - © angellodeco - stock.adobe.com
March 26th 2023

Use of Pain, Depression, Anxiety Meds Higher Among Patients With Hemophilia

Jaime Rosenberg
This analysis found that the 3000 patients with hemophilia had higher rates of pain, depression, and anxiety medication use.
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March 21st 2023

Study Examines Changes in Hemophilia Prescribing Practices Since 1999

Allison Inserro
Specific dosing regimens of treatments prescribed by blood specialists have not been widely studied, despite the advent of newer hemophilia therapies, the researchers said.
Image of blood analysis: blindturtle - stock.adobe.com
March 18th 2023

Group Develops Measure They Say Could Help Tailor Hemophilia Treatment

Jaime Rosenberg
The measure will allow for a more complete picture of treatment burden and how it affects things like health-related quality of life and adherence, explained researchers.
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March 16th 2023

BMD Reduced, but Stable Throughout Course of Hemophilia, Say Findings

Jaime Rosenberg
Prior to this study, explained researchers, data on the long-term course of osteoporosis, as evaluated through bone mineral density (BMD) in these patients, have been lacking.
Lab tech holding test tube with blood: curlymary - stock.adobe.com
March 11th 2023

Rare Risk of Acquired Hemophilia A Seen Following COVID-19 Infection, Vaccination

Jaime Rosenberg
A group of researchers detailed a case of acquired hemophilia A (AHA) following infection and again following vaccination, and provided additional insights through their systematic review of available data.
image of blood vessels
March 10th 2023

FVIII Half-life in Patients With Hemophilia Largely Determined by Clearance of VWF

Jaime Rosenberg
These new findings suggest that variability in factor VIII (FVIII) half-life in patients, though impacted by all 3 factors, is largely attributed to variability in the clearance of endogenous von Willebrand factor (VWF).
Image of a doctor examining a digital image of a heart
February 26th 2023

Researchers Outline CVD Management Approach in Patients With Hemophilia

Jaime Rosenberg
The approach for cardiovascular disease (CVD) was based on expert opinion, personal experience, and adaptation of evidence from people who did not have hemophilia.
Image of Andexxa
February 22nd 2023

Andexanet Alfa Fully Neutralizes Anticoagulation From Thrombotic Disorder Treatment

Jaime Rosenberg
Researchers found that the anticoagulant effects of apixaban, betrixaban, edoxaban, and rivaroxaban were partially neutralized at an andexanet alfa dose of 50 mcg/mL and were completely neutralized at 100 mcg/mL.
Image of a stethoscope next to a globe
February 19th 2023

Researchers Explore Ethical Considerations for Gene Therapy in Hemophilia

Jaime Rosenberg
The second half of 2022 brought the first gene therapies for hemophilia to the market in both the United States and abroad.
Blood flowing
February 14th 2023

Early Factor VIII Prophylaxis Initiation Associated With Long-term Joint Status Preservation in Hemophilia A

Rose McNulty
Early initiation of prophylaxis regimens and joint status monitoring over time are the most relevant aspects of evaluating treatment efficacy in this patient population, study authors concluded.
Image of a lab technician running blood tests
February 13th 2023

FVIII Inhibitory Antibody Titer Shows Implications for Response to IST Treatment for AHA

Jaime Rosenberg
Data show that patients who have factor VIII (FVIII) inhibitor titers of 20 or higher BU/mL took longer to achieve complete responses (CR) and had lower CR rates vs patients with lower titers.
image of blood tests
February 11th 2023

Despite High False-Positive Rate of FIT, Patients With Hemophilia Have High CRC Detection Rate

Jaime Rosenberg
The researchers underscored the importance of their findings for a wide group of patients with inherited bleeding disorders, as most colorectal cancer (CRC) screening programs across the globe use fecal immunochemical testing (FIT).
image of blood pressure monitor
February 10th 2023

Systematic Strength Training Protocols May Benefit People With Hemophilia

Pearl Steinzor
Strength training for people with hemophilia (PwH) should consider exercise variables and pain threshold, a review finds.
What We’re Reading: J&J Ends HIV Vaccine Trial; Deaths After Abortion Bans; Sanofi Looks to Hemophilia A Drug
January 19th 2023

What We’re Reading: J&J Ends HIV Vaccine Trial; Deaths After Abortion Bans; Sanofi Looks to Hemophilia A Drug

AJMC Staff
Johnson & Johnson (J&J) ends late-stage HIV vaccine trial; mothers in states with abortion bans are almost 3 times more likely to die before, during, and after birth; Sanofi hopes to release a drug for hemophilia A in 2023.
Graphic with the title and health icons
December 23rd 2022

Top 5 Most-Read Hemophilia Articles of 2022

Justina Petrullo
The most-read hemophilia articles of the year highlighted new drug developments for hemophilia, the impact of carrier status, and opportunities for better patient education.
Male patient and doctor
December 7th 2022

Safety and Efficacy of New Hemophilia Treatments Are Most Important, Patients Report

Justina Petrullo
Safety and efficacy were the most important factors for patients with hemophilia learning about gene therapies, although more research is needed to see how collaboration between providers and patients contributes to the best outcomes.
map of europe
November 26th 2022

Access to Genetic Testing in Europe for Hemophilia Needs Improvement, Study Says

Allison Inserro
Optimized hemophilia care requires rapid, accurate, and high-quality genetic testing, but access to these tests varies across the European Union, according to a recent study.
global health image
November 25th 2022

Current Research and Logistical Considerations for Gene Therapy in Hemophilia

Rose McNulty
A recent review poses gene therapy as a novel treatment option with potential to reduce health care disparities globally.
What We're Reading
November 23rd 2022

What We’re Reading: Increase in People Seeking Coverage; Monkeypox Name Change; Hemophilia Gene Therapy Approved

AJMC Staff
The HHS announced an increase in individuals seeking coverage from Healthcare.gov; monkeypox will receive a name change to destigmatize the virus; a gene therapy for hemophilia was approved and is now the most expensive in the world.
Offbeat image of research
November 11th 2022

NSAIDs May Be Safe for Use in Hemophilia, but More Research Is Needed

Rose McNulty
The hesitation to prescribe nonsteroidal anti-inflammatory drugs (NSAIDs) to patients with hemophilia is not supported by current research, based on a recently published review, but the available studies had significant limitations.
graphic depicting genetic therapy
November 6th 2022

Cost-Savings Model Estimates Reduced Economic Burden With Gene Therapy for Hemophilia A

Rose McNulty
Gene therapy is a novel approach to hemophilia A treatment that carries a substantial cost up front but may lead to cost savings compared with current prophylaxis agents in the long run.
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