Hemophilia

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More News

August 23rd 2023

Patients, Clinicians Need Hemophilia Gene Therapy Shared Decision-Making Tool

Victoria Johnson

Clinicians and nurses who treat patients with hemophilia with a gene therapy identified important factors and considerations needed in a potential shared decision making tool.

August 18th 2023

National Hemophilia Foundation Updates Name to National Bleeding Disorders Foundation

AJMC Staff

A 75-year-old foundation updates its name to reflect a more comprehensive mission.

Asian doctor checking on African baby boy in mother's arms. Healthcare for baby concept: © Dollydoll - stock.adobe.com

May 8th 2023

There Is Much to Consider and Discuss in Previously Untreated Hemophilia

Treatment options have improved care, but also increased the need for patient education.

Blood sample positive with hemophilia disease: © jarun011 - stock.adobe.com

May 5th 2023

Bleeding, Damage Common in Pediatric Hemophilia Despite Prophylaxis

About a quarter of joints examined had at least 1 joint bleed.

Service Satisfaction Indicator: © Olivier Le Moal - stock.adobe.com

May 1st 2023

Dutch Hemophilia Patients Report Satisfaction With Care

However, the patients also said they worried about insufficient care coordination between specialists and other care providers.

picture of tubes of blood labels with the word hemeophilia

April 25th 2023

New Recombinant Factor IX Leads to Significant Cost Savings in Hemophilia B

The projected cost reductions held both for patients switching from a different extended-half-life product and for patients switching from a standard-half-life product.

Medical Team Performing Surgical Operation in Modern Operating Room: © Gorodenkoff - stock.adobe.com

April 21st 2023

Patients With Bleeding Disorders Face Similar Surgery Risks to Healthy Controls

Gianna Melillo

Little is known about the risk of bleeding in patients with bleeding disorders who undergo major surgeries or outcomes for those managed perioperatively at hemophilia treatment centers.

Back view of strong motivated woman celebrating workout goals towards the sun. Morning healthy training success: © Dirima - stock.adobe.com

April 14th 2023

Certain Exercises Well Tolerated by Patients With Severe Hemophilia

Gianna Melillo

Recommendations are lacking on strength exercise intensity, tolerability, and adverse effects for patients with severe forms of hemophilia.

Hands holding a drop of blood, blood donation, blood transfusion, world blood donor day, world hemophilia day concept: © Rodrigo Rivas - stock.adobe.com

April 11th 2023

Many Patients With Hemophilia Experience Functional Declines Over Time

Gianna Melillo

Study authors determined that regular musculoskeletal assessments can help facilitate personalized care for patients who have hemophilia, in that they can detect changes early.

Ankle twist sprain accident in sport exercise running jogging: © mansong - stock.adobe.com

March 30th 2023

Pain May Predict Impaired Outcomes in Patients With Hemophilia and Ankle Hemarthropathy

Hemarthropathy in multiple joints is a common feature of more severe forms of hemophilia, with the ankle joint often being reported as the main site of pain.

Doctor working with tablet in hands in the lab with message hemophilia - © angellodeco - stock.adobe.com

March 26th 2023

Use of Pain, Depression, Anxiety Meds Higher Among Patients With Hemophilia

This analysis found that the 3000 patients with hemophilia had higher rates of pain, depression, and anxiety medication use.

March 21st 2023

Study Examines Changes in Hemophilia Prescribing Practices Since 1999

Allison Inserro

Specific dosing regimens of treatments prescribed by blood specialists have not been widely studied, despite the advent of newer hemophilia therapies, the researchers said.

Image of blood analysis: blindturtle - stock.adobe.com

March 18th 2023

Group Develops Measure They Say Could Help Tailor Hemophilia Treatment

The measure will allow for a more complete picture of treatment burden and how it affects things like health-related quality of life and adherence, explained researchers.

Image of bones with osteoporosis: adimas - stock.adobe.com

March 16th 2023

BMD Reduced, but Stable Throughout Course of Hemophilia, Say Findings

Prior to this study, explained researchers, data on the long-term course of osteoporosis, as evaluated through bone mineral density (BMD) in these patients, have been lacking.

Lab tech holding test tube with blood: curlymary - stock.adobe.com

March 11th 2023

Rare Risk of Acquired Hemophilia A Seen Following COVID-19 Infection, Vaccination

A group of researchers detailed a case of acquired hemophilia A (AHA) following infection and again following vaccination, and provided additional insights through their systematic review of available data.

March 10th 2023

FVIII Half-life in Patients With Hemophilia Largely Determined by Clearance of VWF

These new findings suggest that variability in factor VIII (FVIII) half-life in patients, though impacted by all 3 factors, is largely attributed to variability in the clearance of endogenous von Willebrand factor (VWF).

Image of a doctor examining a digital image of a heart

February 26th 2023

Researchers Outline CVD Management Approach in Patients With Hemophilia

The approach for cardiovascular disease (CVD) was based on expert opinion, personal experience, and adaptation of evidence from people who did not have hemophilia.

February 22nd 2023

Andexanet Alfa Fully Neutralizes Anticoagulation From Thrombotic Disorder Treatment

Researchers found that the anticoagulant effects of apixaban, betrixaban, edoxaban, and rivaroxaban were partially neutralized at an andexanet alfa dose of 50 mcg/mL and were completely neutralized at 100 mcg/mL.

February 19th 2023

Researchers Explore Ethical Considerations for Gene Therapy in Hemophilia

The second half of 2022 brought the first gene therapies for hemophilia to the market in both the United States and abroad.

February 14th 2023

Early Factor VIII Prophylaxis Initiation Associated With Long-term Joint Status Preservation in Hemophilia A

Rose McNulty

Early initiation of prophylaxis regimens and joint status monitoring over time are the most relevant aspects of evaluating treatment efficacy in this patient population, study authors concluded.

Image of a lab technician running blood tests

February 13th 2023

FVIII Inhibitory Antibody Titer Shows Implications for Response to IST Treatment for AHA

Data show that patients who have factor VIII (FVIII) inhibitor titers of 20 or higher BU/mL took longer to achieve complete responses (CR) and had lower CR rates vs patients with lower titers.

February 11th 2023

Despite High False-Positive Rate of FIT, Patients With Hemophilia Have High CRC Detection Rate