April 16th 2024
The therapy bridges activated factors IX and X to mimic the function of missing or deficient factor VIII.
Managed Care Considerations on the Evolving Role of Bispecific Antibodies in Hematologic Malignancies
1.5 Credits / Hematology, Oncology
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Continuing the Conversation in Myelofibrosis: The Role of Managed Care in Supporting Treatment Goals Through Appropriate Use of Emerging Therapies
1.0 Credits / Hematology, Oncology
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Supporting Safe, Effective, and Equitable Access to B-Cell Maturation Antigen (BCMA)-Directed Treatments in Multiple Myeloma: Strategies for Specialty and Managed Care Pharmac...
1.5 Credit / Hematology, Oncology
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Advances in the Treatment of Myelofibrosis: Updates and Considerations for Managed Care Professionals
1.0 Credit / Hematology, Oncology
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Andexanet Alfa Fully Neutralizes Anticoagulation From Thrombotic Disorder Treatment
February 22nd 2023Researchers found that the anticoagulant effects of apixaban, betrixaban, edoxaban, and rivaroxaban were partially neutralized at an andexanet alfa dose of 50 mcg/mL and were completely neutralized at 100 mcg/mL.
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FVIII Inhibitory Antibody Titer Shows Implications for Response to IST Treatment for AHA
February 13th 2023Data show that patients who have factor VIII (FVIII) inhibitor titers of 20 or higher BU/mL took longer to achieve complete responses (CR) and had lower CR rates vs patients with lower titers.
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Despite High False-Positive Rate of FIT, Patients With Hemophilia Have High CRC Detection Rate
February 11th 2023The researchers underscored the importance of their findings for a wide group of patients with inherited bleeding disorders, as most colorectal cancer (CRC) screening programs across the globe use fecal immunochemical testing (FIT).
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Safety and Efficacy of New Hemophilia Treatments Are Most Important, Patients Report
December 7th 2022Safety and efficacy were the most important factors for patients with hemophilia learning about gene therapies, although more research is needed to see how collaboration between providers and patients contributes to the best outcomes.
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NSAIDs May Be Safe for Use in Hemophilia, but More Research Is Needed
November 11th 2022The hesitation to prescribe nonsteroidal anti-inflammatory drugs (NSAIDs) to patients with hemophilia is not supported by current research, based on a recently published review, but the available studies had significant limitations.
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Cost-Savings Model Estimates Reduced Economic Burden With Gene Therapy for Hemophilia A
November 6th 2022Gene therapy is a novel approach to hemophilia A treatment that carries a substantial cost up front but may lead to cost savings compared with current prophylaxis agents in the long run.
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ICER Releases Draft Evidence Report on Gene Therapies for Hemophilia A and B
September 17th 2022Despite $2.5 million placeholder price tags, the Institute for Clinical and Economic Review draft evidence report considers gene therapy cost-effective versus comparators in both hemophilia A and B.
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Review Looks at Impact of SDOH on Bleeding Disorders
September 9th 2022More than 3 million Americans have inherited bleeding disorders, and social determinants of health (SDOH) play a role in a number of ways, including cost for treatment, difficulty accessing specialists, educational barriers, and more.
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Case Study Chronicles Onset and Treatment of Acquired Hemophilia A Following HSCT for ALL
September 6th 2022The case emphasizes the importance for clinician awareness of the potential for rare immune-mediated disorders, including acquired hemophilia A (AHA), following allogeneic hematopoietic stem cell transplantation (HSCT).
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Systematic Approaches to Patient Educational Needs May Benefit Those With Bleeding Disorders
September 2nd 2022Nurse-led education is an essential aspect of care for patients with bleeding disorders, but there is currently a lack of research on specific strategies to improve patient self-management through education.
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Gaps Remain Between European Regions for Hemophilia Care Despite Improvements
July 17th 2020Hemophilia care principles have been on the rise in Europe over the course of the last decade, however, differing regions and policies on the continent reveal gaps in access to various treatments and specialty services.
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Prevalence of Hemophilia Worldwide Is Triple That of Previous Estimates, New Study Says
September 10th 2019The meta-analysis showed that more than 1,125,000 men around the world have the inherited bleeding disorder; 418,000 of those have a severe version of the mostly undiagnosed disease. Previously, only 400,000 people globally were estimated to have hemophilia.
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