Infectious Disease

The AJMC® Infectious Disease compendium is a comprehensive resource for news and interviews about the viruses, bacteria, fungi, and parasites that create illness and outbreaks.

Latest News

MMR vaccine vial - Leigh Prather - AdobeStock_283415438.jpeg
Falling Vaccination Rates May Bring Back Measles, Polio in US

June 24th 2025

Model predicts millions of cases, hospitalizations, and deaths if routine childhood vaccination rates decline significantly.

Mental health recovery | Image Credit: Maggie L. Shaw/sora.chatgpt.com
Prolonged Mental Health Recovery Linked to Long COVID

June 10th 2025

One dose of the MMR vaccine provides 95% protection against measles, and 2 doses of the MMR vaccine are 97% effective against measles. - Image Credit: Leigh Prather - stock.adobe.com
CDC Urges All International Travelers to Be Vaccinated Against Measles

June 3rd 2025

nikitos - stock.adobe.com
ACP Experts Say FDA, CDC Moves May Undermine COVID-19 Vaccine Coverage for Millions

June 2nd 2025

COVID-19. | Image Credit: Production Perig - stock.adobe.com
The Argument Against Routine Antibiotics for Patients With Nonsevere COVID-19

May 19th 2025

Advancing UTI Treatment: Highlights from IDWeek 2024

Discover groundbreaking research on urinary tract infections, including findings from the EAGLE-2 and EAGLE-3 trials. Learn how gepotidacin, a first-in-class oral therapy, addresses antimicrobial resistance and unmet needs in UTI management.

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Continuing Medical Education
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June 26th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology
June 26th 2025

Advancing Immunotherapy in Endometrial Cancer: A Managed Care Perspective on Personalized Care

1.5 Credits / Gynecologic Cancer, Health Equity, Diversity & Inclusion, Oncology, Women's Health

More News

What We're Reading: FTC Launches PBM Inquiry; FDA Advisers Recommend Novavax; Drug Prices Soar
June 8th 2022

What We're Reading: FTC Launches PBM Inquiry; FDA Advisers Recommend Novavax; Drug Prices Soar

AJMC Staff
The Federal Trade Commission (FTC) launched an inquiry into the practices of pharmacy benefit managers; FDA advisers overwhelmingly support approval of Novavax, a new COVID-19 vaccine; drug prices soar to 20% annual inflation.
patient speaking with doctor
May 28th 2022

Treatments That Leverage SCFAs May Be Effective in Clostridioides difficile Infection

Jaime Rosenberg
Citing outbreaks of Clostridioides difficile infection in both America and Europe, the researchers emphasized the need for more effective treatments.
Microbiome
May 24th 2022

Investigational Biotherapeutic Offers Relief From CDI Recurrence by “Filling in the Cracks” in the Microbiome

Christina Mattina
Abstracts presented at Digestive Disease Week 2022 showed that RBX2660, an investigational microbiota-based drug, was more likely to reduce the recurrence of Clostridioides difficile infection (CDI) compared with placebo.
Microbiota in gut
May 22nd 2022

Posters Show Success of RBX2660 in Reducing C difficile Recurrence, Reviving Microbiome

Christina Mattina
A pair of posters presented at Digestive Disease Week 2022 showed the efficacy of an investigational biotherapeutic in preventing Clostridioides difficile infection recurrence and restoring the microbiome.
Robin Gelburd, JD
May 19th 2022

Contributor: Most Diagnosed With Long COVID Were Never Hospitalized

Robin Gelburd, JD
The latest report from FAIR Health shows that the majority of people diagnosed post-COVID condition were never hospitalized.
Image of HPV vaccines
May 16th 2022

HPV Rates Continue to Decline, New Data Suggest Herd Immunity Growing

Jared Kaltwasser
Experts warn, however, that human papillomavirus (HPV) vaccinations missed because of the COVID-19 pandemic could stymie this progress.
Image of a hospital
May 11th 2022

Clostridioides difficile Infection May Be Underdiagnosed in Health Care Facilities, Study Finds

Rose McNulty
A study of hospitals and long-term care facilities in Louisville, Kentucky, found low rates of Clostridioides difficile testing in patients with new-onset diarrhea who are frequently infected.
Graphic of hospital setting
May 8th 2022

SHEA Updates Guidelines for Central Line-Associated Bloodstream Infection Prevention in Hospitals

Rose McNulty
Preventing health-care–associated infections in acute-care hospitals is crucial for patient well-being and health care cost burden, and comprehensive guidelines based on current research are an important aspect of prevention.
FDA Approves First Drug for Recurrent Vulvovaginal Candidiasis
May 4th 2022

FDA Approves First Drug for Recurrent Vulvovaginal Candidiasis

AJMC Staff
The drug, oteseconazole, is an azole antifungal indicated to reduce the incidence of recurrent vulvovaginal candidiasis in females who are infertile or postmenopausal.
Gastrointestinal
May 2nd 2022

Study Gives Insight Into Fidaxomicin’s Gut-Sparing Activity in Clostridioides difficile

Jaime Rosenberg
Fidaxomicin, now commonly used to treat Clostridioides difficile infection, selectively targets the bacterium while sparing crucial gut commensals that protect against colonization. However, knowledge gaps in the molecular basis of its narrow-spectrum activity remain.
Study: Effective Treatment Significantly Improves HRQoL in Recurrent Clostridioides difficile
April 30th 2022

Study: Effective Treatment Significantly Improves HRQoL in Recurrent Clostridioides difficile

Jaime Rosenberg
The researchers wrote that their findings showcase the need for close monitoring of patients and for effective treatments for those with recurrent infection, which occurs in 15%-30% of all patients with Clostridioides difficile.
Graphic of SARSCOV2
April 26th 2022

SARS-CoV-2 Seroprevalence Study Shows Most Americans, Especially Children, Have Prior Evidence of Infection

Allison Inserro
The CDC said that 75% of children under age 17 and more than 60% of adults up to age 49 have evidence of prior infection with SARS-CoV-2, the virus that causes COVID-19.
flu vaccine vials
April 23rd 2022

Study Finds Self-reported Historical Influenza Vaccination Status Reliable in Most Health Care Personnel

Rose McNulty
Self-reported vaccination statuses are often used in studies of influenza vaccination, and a recent study found this method reliable in health care personnel who receive the vaccine consistently. 
pollution image
April 19th 2022

How Can the Health Care Industry Help Tackle Climate Change?

Gianna Melillo
In a talk presented by The Hastings Center, Gary Cohen, president of Health Care Without Harm, explains how the health care industry can fight climate change, mitigate social determinants of health, and reduce costs through a series of targeted efforts.
dna image
April 18th 2022

Alternative K-mer–Based Approaches Offer Faster Clostridioides difficile Genome Analysis, but Leave Room for Improvement

Rose McNulty
As more bacterial DNA sequences are identified, the computational challenges associated with whole-genome sequencing have researchers looking to other potential methods of tracking and understanding differences in bacterial pathogens such as Clostridioides difficile.
White pills
April 9th 2022

Underinsurance as a Persistent Driver of Cross-Border Antibiotic Procurement in US Border Communities

Rose McNulty
Cross-border acquisition of medications such as antibiotics has long been a practice in US communities bordering Mexico, and a lack of sufficient insurance is one driver of the trend, according to a recent study.
image of china on globe
April 8th 2022

Over 100 Infectious Diseases Identified Among Chinese Population Over 4 Years

Jaime Rosenberg
In addition to the 35 notifiable infectious diseases, 95 infectious diseases not required to be reported to public health authorities were also uncovered by the population-based observational study.
medical cross
April 1st 2022

Real-World Data Suggest Fidaxomicin Reduces Clostridioides difficile Reinfection Versus Vancomycin

Rose McNulty
Both fidaxomicin and vancomycin are recommended for treatment of Clostridioides difficile infections, but real-world data suggest fidaxomicin should be the go-to treatment option.
Newspapers
April 1st 2022

What We're Reading: COVID-19 Funding Bill; Entire Human Genome Sequenced; Pandemic Impact on Teen Mental Health

AJMC Staff
Democrats and Republicans are near agreement on a $10 billion COVID-19 funding package; scientists perform the first complete, gapless sequence of a human genome; more than a third of high school students reported they experienced poor mental health during the pandemic.
Image of C diff bacteria
March 27th 2022

Study Finds Low Natural Antibody Response to Clostridioides difficile

Rose McNulty
The presence of antigen-specific and neutralizing antibodies was not associated with Clostridioides difficile infection symptoms, severity, therapy approach, treatment response, or recurrences in a new exploratory study.
pair of hands of elderly person
March 23rd 2022

Reducing Mortality, Economic Burden of Clostridioides difficile Infection in Older Adults

Rose McNulty
Improving the prevention and diagnosis of primary Clostridioides difficile infection in older adults could reduce mortality and economic burden, according to recent research.
What We're Reading
March 21st 2022

What We’re Reading: Curbing Medical Debt Reports; Omicron Antibody Treatment; Middle, High School Tobacco Use

AJMC Staff
Starting July 1, credit-reporting giants will remove certain medical debts; AstraZeneca’s Evusheld was shown to reduce the viral load of subvariants BA.1, BA1.1, and BA.2; about 4% of middle school students and 13% of high school students use some type of tobacco product, according to a report.
Image of a medical clinic
March 17th 2022

Study Finds C difficile Infection Manageable in Primary Care Settings With Specialist Guidance

Rose McNulty
Cases of Clostridioides difficile (C diff) have increasingly been reported outside of typical settings, and a survey of general practitioners in France found that many cases can be managed without hospitalization.
Picture of the White House
March 2nd 2022

Looking Beyond COVID-19, US Health Officials Outline Next Steps to Fight Disease

Allison Inserro
From one-stop testing and treatment sites to boosting research and surveillance, Biden administration health officials expanded on the COVID-19 plan the president announced in his State of the Union address Tuesday night, but the plan will require additional funding from Congress.
Expert on C. Difficile
December 23rd 2021

Challenges in the Management of C. Diff Infection

Neil Minkoff, MD Dale N. Gerding, MD Kevin U. Stephens, Sr, JD, MD Jessica Allegretti, MD, MPH Karina Abdallah, PharmD
Panelists take a step back to consider the broader challenges in managing patients with clostridium difficile infection.
Peter Hotez, MD
December 21st 2021

Dr Peter Hotez on Combatting Antivaccination Beliefs and Rescuing Public Health From Politics

Maggie L. Shaw Allison Inserro
In an interview conducted before the highly transmissible Omicron coronavirus variant began driving another wave of infections, Peter Hotez, MD, PhD, FASTMH, discussed the struggle public health officials and scientists have in fighting false beliefs about vaccinations.
Top 5 Infectious Disease Content of 2021
December 21st 2021

Top 5 Infectious Disease Content of 2021

This year's most-viewed content in infectious disease was dominated by COVID-19, as the Delta variant continued to strain the US health care system. It also included news about Clostridioides difficile.
Community Oncology Leaders Find Silver Linings in the Pandemic
December 20th 2021

Community Oncology Leaders Find Silver Linings in the Pandemic

Maggie L. Shaw
Debra Patt, MD, PhD, MBA, of Texas Oncology, and Lucio Gordan, MD, of Florida Cancer Specialists, MD, presented data from a study they conducted in partnership with the Community Oncology Alliance and Avalere Health.
Dr Leslie Kantor: Mild Flu Seasons Make Future Vaccine Matching Tricky
December 18th 2021

Dr Leslie Kantor: Mild Flu Seasons Make Future Vaccine Matching Tricky

When a flu season is mild, it can make developing a vaccine for the following season a bit more difficult as it can be hard to find the right match, but on the other hand, the US health system could benefit from less stress this winter given the unrelenting demands posed by COVID-19, says Leslie Kantor, PhD, MPH, chair and professor of the Department of Urban-Global Public Health, Rutgers School of Public Health.
Expert on C. Difficile
December 16th 2021

Payer Perspectives on Risk Stratification for CDI Recurrence

Neil Minkoff, MD Dale N. Gerding, MD Jessica Allegretti, MD, MPH Kevin U. Stephens, Sr, JD, MD Karina Abdallah, PharmD
Payer participants consider how they proactively risk stratify patients for clostridium difficile infection recurrence.
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