Myeloproliferative Neoplasms (MPN)

Latest News

One of the key ways to manage thromboembolic event risk in PV is by controlling hematocrit, often by prescribing hydroxyurea. If patients develop resistance to the therapy, however, they face a higher risk of mortality. | Image credit: keetazalay - stock.adobe.com
Machine Learning Model Identifies Hydroxyurea Resistance Markers in PV

May 6th 2025

Machine learning identifies key biomarkers predicting hydroxyurea resistance in polycythemia vera, enhancing early treatment strategies and patient outcomes.

The results offer some of the first glimpses into real-world findings of the JAK inhibitor momelotinib, which was approved in 2023. | Image credit: mdaros - stock.adobe.com
Real-World Findings Confirm Clinical Data on Momelotinib in MF With Anemia

May 1st 2025

The investigators found that people with MPNs and at least one CVRF had an increased risk of both death and arterial or venous thrombosis. | Image credit: Dr_Microbe - stock.adobe.com
Cardiovascular Risk Factors Impact Outcomes in MPNs

April 21st 2025

In Charleston, West Virginia, Tracking MPN Symptoms Becomes a Priority
In Charleston, West Virginia, Tracking MPN Symptoms Becomes a Priority

January 17th 2025

Supportive Care | Image credit: Pexels photo
Kent Hospital MPN Initiative Focuses on Supportive Care

January 16th 2025

AJMC Provides Myelofibrosis Guideline Updates

Watch the series now!

AJMC Provides Myelofibrosis Guideline Updates

More News

Primary myelofibrosis cells | Image credit: LASZLO - stock.adobe.com
March 16th 2024

Disease-, Age-, Genomic-Specific Factors Increase Risk of ET, PV, PrePMF Developing Into Overt MF

Laura Joszt, MA
New research highlights the factors that increase the likelihood that essential thrombocytopenia (ET), polycythemia vera (PV), and prefibrotic primary myelofibrosis (PrePMF) will evolve into overt myelofibrosis (MF).
Polycythemia vera red blood cells | Image credit: Dr_Microbe - stock.adobe.com
March 13th 2024

Patients With MPNs Have Increased Risk of Thrombosis, Hemorrhage, Leukemic Transformation

Laura Joszt, MA
Compared with matched controls, patients with myeloproliferative neoplasms (MPNs) had a higher risk of developing thrombosis, hemorrhage, and leukemic transformation, according to a longitudinal cohort study.
Distressed young woman of color | Image credit: Diego Cervo - stock.adobe.com
March 8th 2024

AYA With MPN Face Psychological Needs That Are Poorly Understood

Laura Joszt, MA
A review of research confirms that adolescents and young adults (AYA) with myeloproliferative neoplasms (MPN) face psychological burdens but the exact burden is poorly understood.
National Comprehensive Cancer Network (NCCN) logo | Image credit: NCCN
March 6th 2024

NCCN Lists Ropeginterferon Alfa-2B as Preferred First-Line Cytoreductive Therapy for Polycythemia Vera

Ashling Wahner
The National Comprehensive Cancer Network (NCCN) recommends ropeginterferon alfa-2b as first-line cytoreductive therapy for polycythemia vera.
Screenshot of Jennifer Vaughn, MD, in a Zoom video interview
March 1st 2024

Dr Jennifer Vaughn: Patients With MPN, MDS Should Discuss Long-Term Priorities Upfront

Laura Joszt, MA Justina Petrullo
For many patients with myeloproliferative neoplasms (MPNs) and myelodysplastic syndromes (MDS), their disease will be chronic, giving them a long-term cancer experience, said Jennifer Vaughn, MD, of The Ohio State University Comprehensive Cancer Center – James Cancer Hospital.
Doctor Measuring arterial blood pressure man patient Health care in hospital | joyfotoliakid - stock.adobe.com
December 7th 2023

Reducing Cardiovascular Risk in Patients With Polycythemia Vera

Pearl Steinzor
Polycythemia vera (PV) therapy should aim to identify cardiovascular risk factors, according to one review.
Diagnosis of Myelofibrosis. Laboratory blood bottle (tube), glass slide with blood smear, hematology test, stethoscope lying on notebook with printed text hematological diagnosis of Myelofibrosis | shidlovski - stock.adobe.com
November 17th 2023

Enhancing Outcomes and Quality of Life for Patients With Myelofibrosis

Pearl Steinzor
A phase 3 trial in symptomatic and anemic patients with myelofibrosis (MF) met its primary end point, seeing a significant symptom reduction at 24 weeks with momelotinib vs danazol.
Rare diseases inscription words. Medical concept of unusual disorders | valiantsin - stock.adobe.com
October 24th 2023

The Effects of Aging on Profiling Epigenetic Changes in Myeloproliferative Neoplasms

Pearl Steinzor
Researchers identified distinct patterns of epigenetic dysregulation in myeloproliferative neoplasms.
Myeloproliferative Disorders. Myeloproliferative Disorders disease blood test inmedical laboratory: © luchschenF - stock.adobe.com
May 15th 2023

Review Highlights Features, Treatment of Budd-Chiari Syndrome in MPNs

Gianna Melillo
Budd-Chiari syndrome and myeloproliferative neoplasms (MPNs) are rare, which means available data are limited.
Yoga
November 12th 2020

Integrative Medicine Shows Benefits for Patients With MPNs

Jaime Rosenberg
A recent survey of patients with myeloproliferative neoplasms found integrative medicine interventions improved symptom burden, fatigue, depression, and improved quality of life.
<12

2 Commerce Drive
Suite 100
Cranbury, NJ 08512

© 2025 MJH Life Sciences® and AJMC®.
All rights reserved.

About
Contact
Editorial Boards
Advertise
Do Not Sell My Information
Terms & Conditions
Privacy Policy
AJMC Managed Markets Network Logo
CH LogoCenter for Biosimilars Logo