Psoriasis

The AJMC® Psoriasis compendium is a comprehensive resource for clinical news and expert insights for the chronic skin disease, which tends to go through cycles where it flares and goes into remission.

Latest News

Adalimumab | Image credit: luchschenF - stock.adobe.com
Methotrexate Adds No Benefit to Adalimumab in Psoriasis Treatment, Study Suggests

June 16th 2025

Target trial emulation study finds no added effectiveness or persistence with combination therapy for plaque psoriasis.

Psoriasis | Image credit: SergeVo - stock.adobe.com
Low BSA in Psoriasis May Still Mean High Disease Burden

June 12th 2025

Psoriasis skin, eczema, rash and other skin diseases. | Image credit: stockmaster - stock.adobe.com.jpg
Patients With GPP Face Elevated Mortality Risk, Study Finds

June 3rd 2025

woman with psoriasis | Image credit: Andrey Popov - stock.adobe.com
Biosimilar Starjemza Gains FDA Approval as Ustekinumab Shows Significant Psoriasis-Itch Relief

May 29th 2025

Plaque psoriasis | Image credit: Milan Lipowski - stock.adobe.com
FDA Approves Roflumilast Topical Foam 0.3% for Plaque Psoriasis

May 22nd 2025

A Personalized Approach to Disease Management in Psoriasis

A panel of experts discuss their personalized approaches to treating patients with psoriasis and comorbidities such as metabolic syndrome.

Ryan Haumschild, PharmD, MS, MBA, Bhavesh Shah, PharmD, Mark Lebwohl, MD, and Robert Groves, MD.
Continuing Medical Education
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June 18th 2025

Treatment Gaps in the Management of Generalized Pustular Psoriasis: Enhancing the Role of Managed Care

1.5 Credits / Dermatology, Immunology
June 18th 2025

Advancing Patient Outcomes in Hidradenitis Suppurativa: Updates and Strategies for Managed Care

1.5 Credits / Dermatology

More News

Edward W. Cowen, MD, MHSc.
January 30th 2022

Dr Edward W. Cowen Addresses Current Management of Pustular Psoriasis

Matthew Gavidia
Edward W. Cowen, MD, MHSc, senior clinician and acting branch chief, Dermatology Branch, National Institutes of Health, discusses treatment considerations for patients with different types of pustular psoriasis.
Older person hands.
January 28th 2022

Risankizumab Associated With Improved Skin Clearance vs Secukinumab in Moderate to Severe Psoriasis

Matthew Gavidia
Psoriasis Area and Severity Index scores indicated that patients with moderate-to-severe psoriasis had improved skin clearance when treated with risankizumab compared with secukinumab treatment.
Edward W. Cowen, MD, MHSc.
January 22nd 2022

Dr Edward W. Cowen Discusses Pathophysiology, Treatment of Pustular Psoriasis

Matthew Gavidia
Edward W. Cowen, MD, MHSc, senior clinician and acting branch chief, Dermatology Branch, National Institutes of Health, speaks on cytokines involved in the pathophysiology in pustular psoriasis and off-label therapy use.
Physician treating patient.
January 19th 2022

Patients With Psoriatic Disease, Dermatologists Prefer Specialist-Led Care Model for CVD Prevention

Matthew Gavidia
Patients with psoriatic disease and dermatologists reported their preferred strategies to improve cardiovascular disease risk management, with a specialist-led model of care touted by both groups.
Individualizing Therapy in Patient Subpopulations Without Compromising Contracts
January 18th 2022

Individualizing Therapy in Patient Subpopulations Without Compromising Contracts

The panel closes the program with giving their final thoughts on individualizing therapies for plaque psoriasis and metabolic syndrome in specific patient subpopulations.
Support Services to Help Patient Adherence in Psoriasis
January 18th 2022

Support Services to Help Patient Adherence in Psoriasis

Drs Lebwohl and Groves list support services to help with patient adherence.
Utilizing Lower Volume Agents for Plaque Psoriasis and MetS
January 18th 2022

Utilizing Lower Volume Agents for Plaque Psoriasis and MetS

Bhavesh Shah, PharmD, explains how lower volume agents can be beneficial when treating plaque psoriasis and metabolic syndrome.
Person comforting other individual.
January 15th 2022

Heightened Depressive, Anxiety Burden Found in Patients With Comorbid Psoriasis and PsA

Matthew Gavidia
Patients with comorbid psoriasis and psoriatic arthritis exhibited significantly higher rates of depression and anxiety vs those with psoriasis alone, whereas lifetime suicidality prevalence was not different between the 2 groups but still heightened compared with the general population.
2 physicians working.
January 12th 2022

Adjuvant Ultraviolet-Based Therapy More Effective vs Monotherapy in Psoriasis

Matthew Gavidia
Patients with psoriasis exhibited superior efficacy outcomes when treated with ultraviolet (UV)-based phototherapy plus other adjuvant therapies vs UV monotherapy, with similar safety profiles shown for both approaches.
Utilizing Real-World Evidence for Cost/Value Analyses
January 11th 2022

Utilizing Real-World Evidence for Cost/Value Analyses

Robert Groves, MD, and Bhavesh Shah, PharmD, comment on the role real-world evidence plays in creating cost/value analyses for psoriasis and metabolic syndrome.
Population Health and MetS
January 11th 2022

Population Health and MetS

Dr Groves discusses the impact of population health knowledge in patients with metabolic syndrome.
Person scratching neck.
January 7th 2022

Comorbidities in Patients With Psoriasis Linked With More Severe Skin Lesions, Adverse Treatment Outcomes

Matthew Gavidia
Patients with psoriasis who had comorbidities were associated with worse health-related quality of life and impaired treatment outcomes with conventional therapy, whereas biologic treatments maintained high efficacy despite presence of co-occuring conditions.
Elderly hands.
January 4th 2022

Spesolimab Linked With Higher Incidence of Lesion Clearance, Adverse Reactions in Patients With Pustular Psoriasis

Matthew Gavidia
Treatment with the interleukin-36 inhibitor spesolimab was associated with improved lesion clearance vs placebo after one week, but also a greater incidence of infection and systemic drug reactions.
Identifying Responder and Non-Responders Early in the Psoriasis Treatment Plan
January 4th 2022

Identifying Responder and Non-Responders Early in the Psoriasis Treatment Plan

Dr Lebwohl explains how he can recognize who will respond early to psoriasis treatments and who won’t respond at all.
Switching Among Biologics for Patients With Psoriasis
January 4th 2022

Switching Among Biologics for Patients With Psoriasis

Bhavesh Shah, PharmD, elaborates on switching biologics in psoriasis treatment.
Designing Appropriate Treatment Regimens for Patients With Psoriasis and MetS
December 28th 2021

Designing Appropriate Treatment Regimens for Patients With Psoriasis and MetS

Drs Lebwohl and Groves comment on what they factor in when deciding to switch agents and provide targeted treatments for psoriasis and metabolic syndrome.
Doctor looking at a EHR.
December 27th 2021

Psoriasis Severity, Treatment Outcomes Differ Across US Regions

Matthew Gavidia
Psoriasis severity and treatment outcomes were found to differ across US geographic regions, in which the East South Central and West South Central regions were associated with the greatest frequencies of very severe disease burden and decreased likelihood of achieving targeted response within 6 months of initiating biologic therapy.
Hospitalized child.
December 22nd 2021

Tobacco Exposure May Increase Psoriasis Risk in Children

Matthew Gavidia
Childhood psoriasis was found to be significantly associated with environmental tobacco smoke exposure, whereas intrauterine smoking exposure was not associated with an increased risk in pediatric populations.
Extrapolating Clinical Data for Decision-Making
December 21st 2021

Extrapolating Clinical Data for Decision-Making

Mark Lebwohl, MD, details how he extrapolates clinical data in his decision-making when trying to treat patients with psoriasis.
Payer Considerations When Treating Psoriasis With Different Therapeutics
December 21st 2021

Payer Considerations When Treating Psoriasis With Different Therapeutics

Drs Groves and Lebwohl discuss payer considerations for ensuring treatment with the appropriate agent for patients with psoriasis and metabolic syndrome.
Psoriasis top 5 articles
December 20th 2021

Top 5 Most-Read Psoriasis Articles of 2021

Matthew Gavidia
The top 5 most-read psoriasis articles of 2021 on AJMC.com covered risk factors involved in the pathogenesis and treatment of psoriatic disease and cost considerations for treatment.
Spotlighting a patient.
December 18th 2021

Study Finds No Standardized Treatment, Continued Health Care Utilization in Pustular Psoriasis

Matthew Gavidia
A case series of patients with pustular psoriasis indicated a lack of standardized treatment and continued health care utilization, in which men were at greater risk of an emergency department or hospital encounter.
Doctor and patient.
December 15th 2021

Comorbid Psoriasis, NAFLD Linked With Significantly Impaired Kidney Function

Matthew Gavidia
Patients with comorbid nonalcoholic fatty liver disease (NAFLD) and chronic plaque psoriasis were shown to have significantly lower estimated glomerular filtration rate levels and greater prevalence of more advanced chronic kidney disease.
Effectiveness of Treatment Options in Patients With Psoriasis and MetS
December 15th 2021

Effectiveness of Treatment Options in Patients With Psoriasis and MetS

Bhavesh Shah, PharmD, and Mark Lebwohl, MD, elaborate on treatment effectiveness in patients with both psoriasis and metabolic syndrome.
Increased Risk of Metabolic Syndrome in Patients With Psoriasis
December 15th 2021

Increased Risk of Metabolic Syndrome in Patients With Psoriasis

Drs Lebwohl and Groves discuss patients with psoriasis and the increased risk they have for also being diagnosed with metabolic syndrome.
Patient Adherence With Psoriasis Treatments
December 13th 2021

Patient Adherence With Psoriasis Treatments

Bhavesh Shah, PharmD, and Mark Lebwohl, MD, explain the difficulties of patient adherence to psoriasis treatments.
Disease Burden for Patients With Plaque Psoriasis
December 13th 2021

Disease Burden for Patients With Plaque Psoriasis

Dr Mark Lebwohl explains disease burden for patients with plaque psoriasis and discusses the common comorbidities clinicians see.
Physician with patient.
December 9th 2021

Nail Involvement May Reduce Efficacy of Ustekinumab For Psoriasis

Matthew Gavidia
Nail involvement was shown to reduce the effectiveness of ustekinumab in the treatment of moderate to severe psoriasis, whereas secukinumab exhibited overall higher efficacy than ustekinumab and similar response rates regardless of nail involvement.
Person clasping hand.
December 6th 2021

Patients With Psoriatic Disease May Have Greater Risk of VTE, PVD

Matthew Gavidia
Patients with psoriasis were found to have a more than 20% increased risk of developing incident venous thromboembolism (VTE) and peripheral vascular disease (PVD), with notable at-risk groups including women and those with concomitant psoriatic arthritis.
Person touching neck.
December 2nd 2021

Brodalumab Improves Skin Clearance, QOL vs Ustekinumab in Comorbid Psoriasis, PsA

Matthew Gavidia
Patients with concomitant psoriasis and psoriatic arthritis (PsA) were shown to be 3.1-fold more likely to achieve complete skin clearance when treated with brodalumab vs ustekinumab after 52 weeks, with further improvements reported for quality of life (QOL).
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