Psoriasis

Use of biologics to treat psoriasis may impact prevalence of comorbidities like depression and obesity, according to an abstract presented at the Virtual 2020 International Society for Pharmacoeconomics and Outcomes Research meeting.

A recent analysis describes the effects of the pandemic, including restrictions on outdoor activities and loss of income, on patients with psoriasis in China earlier this year.

Despite some clues, scientists don’t yet understand which patients with psoriasis are likely to eventually develop psoriatic arthritis; solving that riddle could have major impacts on patient care.

Psoriatic arthritis and psoriasis both place a significant economic burden on patients, but a new analysis shows the burden on people with the former is significantly higher.

A patient’s sex, disease duration, and residence were the most common sociodemographic factors shown to affect illness acceptance, life satisfaction, sense of stigmatization, and quality of life among those who have psoriasis, according to the results of a recent study.

Two of the panelists appearing during the Virtual ISPOR 2020 meeting preview what's needed in improving value assessment: Lou Garrison, PhD, of the University of Washington, and Leah Howard, JD, of the National Psoriasis Foundation.

Some oncologists refrain from prescribing checkpoint immunotherapy in patients with Kaposi sarcoma who also have psoriasis or other skin conditions. A new case report says the therapy can be successfully completed while still controlling the skin condition.

Platelet function may aid in determining disease severity for patients with psoriasis who are at an increased risk of developing cardiovascular disease (CVD) and increased inflammation, a review notes.

Guidelines created by the American Academy of Dermatology (AAD) and the National Psoriasis Foundation (NPF) address care management and treatment options for patients with psoriasis in relation to the increased risk of developing inflammatory, cardiovascular, and metabolic conditions.

A new review article finds patients who suffer from psoriatic arthritis (PsA) face a higher risk of type 2 diabetes (T2D), though the exact reasons for the linkage are not yet clear.

Investigators still have a lot to learn about the links among psoriatic arthritis, inflammation, and depression, but a growing body of evidence suggests significant interplay.

A range of new research is helping scientists better understand psoriasis while also raising new questions. One approach is looking at how the gut microbiome affects the disease.

A number of advances have been made in recent years in our understanding of the genetics of psoriatic diseases and psoriatic arthritis specifically. However, those advances have yet to translate into clinically meaningful insights.

Psoriasis typically emerges among the young, while Alzheimer disease is mainly a disorder of old age, raising the question of whether psoriasis has an impact on the later development of neurodegenerative diseases.

The study, with a small sample size, said most patients who take infliximab for more than 6 years report continued efficacy.

In a recently published review, researchers examined the brain-skin connection and the pathogenesis of psoriasis, focusing on the serotonergic system.

Limited data about the effects of psoriasis therapy during pregnancy make it difficult to know which options are possible for pregnant patients and which ones can be harmful, according to a review.

Researchers found a frequent association of depression with psoriasis and atopic dermatitis, according to a descriptive-explorative and retrospective study published in Psychiatry Investigation.

Overall, however, the FDA has reported 12 cases of dyshidrotic eczema caused by secukinumab, the investigators noted.

Research has suggested patients with psoriasis are at a higher risk of hypertension, but a recent meta-analysis aimed to prove the case by looking at tens of thousands of cases.

The combination of the biologic adalimumab and hydroxychloroquine may be responsible for the improvement in lichen planopilaris, including the hair regrowth, according to the study.

The results are in line with earlier studies, and the current review found a link with bladder cancer and lung cancer.

Patients undergoing immunotherapy could be at risk for psoriasis flare-ups, even if the patient is asymptomatic at the initiation of cancer treatment. A newly published case report outlines a rare case where immunotherapy had to be stopped due to severe skin lesions.

Dose reduction of biologics adalimumab, etanercept, and ustekinumab was not shown to be as effective as providing the usual doses for treatment of psoriasis, according to study findings published today.

New research finds salivary antioxidants and oxidative stress could be important biomarkers for plaque psoriasis.