The AJMC® Psoriasis compendium is a comprehensive resource for clinical news and expert insights for the chronic skin disease, which tends to go through cycles where it flares and goes into remission.
Depression, Lack of Efficacy Linked With DMARD Discontinuation in PsA
By year 5 of therapy with disease-modifying anti-rheumatic drugs (DMARDs), only about one-third of patients with psoriatic arthritis (PsA) were expected to be continuing with their therapy.
Biologic Use May Decrease Risk of Psoriatic Arthritis in Patients With Psoriasis
Patients with psoriasis who received biologic treatments were at significantly lower risk of developing psoriatic arthritis, with women representing a potentially at-risk group.
Physical Activity May Lower Risk of Cardiovascular Disease in Patients With Psoriasis
Physical activity was significantly associated with cardiorespiratory fitness and pulse wave velocity, a preclinical indicator of future cardiovascular disease risk, in patients with psoriasis.
Psoriasis Linked With Severe Coronary Calcification, Heart Disease
A recent study aimed to understand whether psoriasis and psoriatic arthritis are independent risk factors for coronary calcification and coronary artery disease. It found both correlate with higher rates of calcification, but only psoriasis was linked with severe calcification and disease.
Study: Psoriatic Arthritis, Joint Pain Drive Analgesic Use in Patients With Psoriasis
A new prospective cohort study suggests joint pain, rather than skin pain or disease severity, correlates with greater use of analgesics.
Analysis Finds Elevated Risk of Psoriasis, Psoriatic Arthritis in Patients With Uveitis
Taiwanese patients with uveitis were shown to be at greater risk of developing psoriasis and psoriatic arthritis than the general population, and hypertension, diabetes, and obesity were more prominent in these populations as well.
Obesity Linked With Lower QOL, Greater Disease Burden in Patients With Psoriatic Arthritis
Patients with psoriatic arthritis and rheumatoid arthritis who were obese were shown to present with significantly lower quality of life (QOL) and worse disease activity than those with normal weight.
Infliximab, Adalimumab Use Associated With Risk of Serious Infection in Patients With Psoriasis
New users of infliximab and adalimumab who had moderate to severe psoriasis exhibited an increased risk of hospitalization due to serious infection compared with etanercept users, with use of ustekinumab conversely linked with a decreased risk.
Assessing Performance of Psoriasis, Atopic Dermatitis Questionnaires Over Time
Researchers investigated whether responses to questionnaires on psoriasis and atopic dermatitis prevalence remained consistent over time.
Low Fitness in Young Adults May Increase Risk of Psoriasis Later in Life
Low cardiorespiratory fitness among young adult men was significantly associated with an increased risk of psoriasis and psoriatic arthritis over 3 decades.
Patients With Psoriatic Arthritis Have Altered Hemostatic Function, Analysis Finds
The new report may help explain why patients with psoriasis have a higher risk of cardiovascular problems.
Psoriasis One of the Most Common Immune-Mediated Diseases Affecting US Adults
Psoriasis is prevalent among more than 7.5 million adults in the United States, a new study says.
Case Reports: Off-label Tildrakizumab Effective in Nail Psoriasis
A new report suggests patients with persistent nail psoriasis may benefit from biologics like tildrakizumab.
Psoriasis Recap: Updated COVID-19 Guidance, Guselkumab Study Results, and More
Recent reports document new COVID-19 guidance for people with psoriatic disease, positive safety and efficacy results for guselkumab, and findings linking the C-Jun protein with psoriasis.
Study: Alcohol Abuse Associated With Poor Therapeutic Response in Psoriasis
Alcohol abuse, obesity, and the use of systemic therapies instead of biologics were all linked with poor response among individuals with psoriasis.
Systemic Therapies Linked With Herpes Zoster Risk in Patients With Psoriasis
Three biologics appeared to increase herpes zoster risk, but 2 other therapies were shown to lower the risk, according to a study of patients in a Taiwanese national database.
Review: Patients With Psoriatic Arthritis Have Increased Rates of Metabolic Syndrome
Results of a systematic review and meta-analysis point to higher rates of metabolic syndrome among patients with psoriatic arthritis.
Exploring the Common Characteristics in Psoriasis and Vitiligo
Both conditions involve a genetic predisposition as well as immune pathways that are triggered by environmental factors.
A Look at Personalized Therapy for Psoriatic Arthritis
A review detailed the initial steps taken into personalized therapeutic options for psoriatic arthritis.
Psoriasis Recap: Investigational Therapies for GPP; How Patients View Remission in PsA
Generalized pustular psoriasis (GPP) may have therapies in a few years; how patients define remission in psoriatic arthritis (PsA).
Untreated Psoriasis and a Cardiac Connection: Lessons From a Case Report
A case of a patient with untreated psoriasis and nonischemic dilated cardiomyopathy (NIDCM) prompted clinicians to encourage study of the rare combination of disease.
Psoriasis Recap: Intermittent Fasting, Microbiome-Skin Links, and More
Updates from 2 recent medical meetings about links between the gut, psoriasis, and other skin disease, as well as the risk of COVID-19.
Pediatric Study Links Psoriasis, T1D
Psoriasis may be associated with an increased prevalence of type 1 diabetes (T1D).
Study Examines Role of Interleukin-30 in Psoriasis
Patients with psoriasis have a higher level of interleukin-30 (IL-30) than healthy patients, according to a recent study.
Longer PASI90 Duration Associated With Better PROs for Patients With Psoriasis
Each month of duration of 90% or more improvement in Psoriasis Are and Severity Index significantly impacted patient-reported outcomes in patients with psoriasis.
COVID-19 Had Negative Impact on Psoriasis Care, Prescription Patterns, Survey Says
Egyptian dermatologists were asked about the effect of COVID‐19 on prescription patterns, appointment rescheduling, therapy decisions, and telemedicine use.
Tildrakizumab Shows Long-term Safety, Efficacy in Patients With Plaque Psoriasis in Japan
The long-term findings come from a subgroup analysis of 120 patients in Japan taking part in an extension of the 3-part, double-blind, randomized, controlled reSURFACE 1 trial.
Case Study Describes Importance of Distinguishing PsA From Other Disorders
If left untreated, patients with psoriatic arthritis (PsA) are at risk of irreversible joint damage, cardiovascular disease, and death. Some other conditions conflated with PsA include chronic eczema, seborrheic dermatitis, onychomycosis, lichen planus, and nodular prurigo.
Patients With Psoriasis May Benefit From Long-term Treatment With Tildrakizumab
Ilumya (tildrakizumab) was shown to be safe and effective in controlling moderate to severe psoriasis for adults through 5 years of treatment in a recent study.
Study Shows Higher Incidence of Psoriasis in Patients With PCOS
A Taiwanese study revealed that attributes associated with polycystic ovary syndrome (PCOS) may increase the risks of those patients developing psoriasis as well.
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