Sleep

Gut microbiome composition, sleep physiology, the immune system, and cognition were found to be interlinked, indicating possible therapies of gut microbiome manipulation to improve sleep quality, according to study findings.

As increasing evidence suggests that a disrupted sleep-wake cycle can drive the development of Alzheimer disease and other neurocognitive disorders via β-amyloid accumulation, a new study finds that the association between β-amyloid accumulation and cognitive impairment can be mediated by sleep disruption even after the onset of cognitive decline.

Insufficient sleep among 2 adolescent groups aged 6-12 and 13-17 was linked with decreased childhood flourishing, a measurement of behavioral and social well-being that affects school performance, as well as, physical and mental health, according to a study to be presented at the American Academy of Pediatrics 2019 National Conference & Exhibition in New Orleans, Louisiana.

Veterans with posttraumatic stress disorder (PTSD), whether or not they had experienced a traumatic brain injury (TBI), were more likely to experience rapid eye movement (REM) sleep behavior disorder than veterans without TBI or PTSD, according to the findings of a new study.

Using and adhering to positive airway pressure therapy was associated with fewer inpatient and overall acute care visits and a lower likelihood of having costs from those visits among patients with moderate or severe obstructive sleep apnea.

Research presented at the 123rd Annual Meeting of the American Academy of Ophthalmology 2019 in San Francisco, California, indicated sleep apnea as a risk factor for diabetic macular edema, a complication of diabetes that can cause vision loss or blindness.

Pairing a sedative with an antidepressant was shown to be potentially beneficial in patients with suicidal thoughts, chiefly those with severe insomnia, according to a study.

A study of college students found that better sleep—specifically, higher quality, longer duration, and greater consistency of sleep—was associated with higher scores on quizzes and midterm exams.

Minority representation in clinical studies often becomes overlooked, which can inhibit attributable research and heightened risk awareness within these subpopulations.

According to results of a survey asking 1300 Americans about their perceptions and knowledge of sleep disorders like narcolepsy, many respondents were not familiar with common symptoms of the disease and their understanding was often shaped by television shows or movies.

According to findings from a cohort study, patients with obstructive sleep apnea were more likely than healthy controls to develop depressive and anxiety disorders over a 9-year follow-up.

A study on zebrafish revealed that the intensity of brain activity during the day, controlling for length of time being awake, is linked to sleep necessity through a neuron named galanin.

The importance of sleep is magnified for patients with Alzheimer disease (AD), who commonly experience sleep disturbances due to changes in their neurotransmitter systems. However, the impact of AD and other dementias on sleep is also seen among caregivers of patients with dementia.

The sleep timing preferences and patterns of adolescent girls are linked to an increased risk for obesity, with weaker, albeit non-significant, associations observed in boys, according to a new study.

Napping during the day 1 or 2 times weekly may lower risk of heart attack and stroke, but no association was found with the duration or greater frequency of naps, according to a new study.

In a new study, researchers compared the associations between several measures of breathing patterns during sleep and daytime sleepiness related to obstructive sleep apnea (OSA). They found that nighttime oxygen desaturation severity was a strong predictor of sleepiness.

Less than 6 hours of sleep, as well as durations of longer than 9 hours, are associated with a greater risk of heart attack, according to a new study.

In individuals undergoing hip arthroscopy in the Military Health System, a diagnosis of sleep apnea or insomnia after the surgery was associated with chronic opioid use, more healthcare visits, and higher medical costs.

Researchers identified a new gene mutation that impacts an individual’s sleep necessity and wakefulness.

A study of pairs of twins revealed that obstructive sleep apnea and measures of the disorder seem to be heritable, but daytime sleepiness is mostly influenced by environmental factors.

During the menopause transition, women with type 2 diabetes are more likely to have sleep disturbances due to an alteration in their hormonal response to insulin.

Prior to the launch of solriamfetol (Sunosi) for narcolepsy and obstructive sleep apnea, the Drug Enforcement Administration designated it as a Schedule IV drug, indicating that it has a low potential for abuse and a low risk of dependence. Around the same time, results from the phase 3 TONES 3 study were published, showing the drug’s efficacy in increasing wakefulness and reducing sleepiness.

Researchers found underlying associations of insomnia with heart disease and stroke.

The clinical manifestations of symptoms experienced by children and adolescents with narcolepsy can differ from those seen in adults, presenting barriers to a timely diagnosis.

Obstructive sleep apnea, a catalyst for higher rates of depression, is a factor in the failure of major depressive disorder treatment, according to a June study published in The Journal of Psychiatric Research.