Sleep

Sleep duration among adolescents aged 9 to 11 was shown to influence elements of mental health, including depression, anxiety, impulsive behavior, and cognitive performance, according to study findings.

Drug developers have made significant strides in understanding narcolepsy in recent years. Now, those advances are translating into a robust pipeline of potential new therapies.

In 2019, the US Department of Defense (DoD) and Department of Veterans Affairs (VA) approved clinical practice guidelines regarding management and treatment of chronic insomnia disorder and obstructive sleep apnea in VA and DoD patients. The VA/DoD Evidence-Based Practice Work Group formulated the framework to enable more effective screening, treatment, and managements of these diseases, according to a review published in Annals of Internal Medicine.

The Narcolepsy Monitor—a companion app for long-term narcolepsy symptom monitoring—may be a helpful tool for gaining insight into the individual burden of narcolepsy symptoms over time and may serve as a patient-reported outcome measure, according to study findings.

In new guidelines issued today by the American Academy of Neurology (AAN), researchers provide sleep intervention recommendations to families, neurologists, and other healthcare providers in making decisions on the best treatments available for children and teens with autism.

Using a deep learning–based model to characterize sleep staging, researchers were able to accurately and automatically detect patients with and without obstructive sleep apnea (OSA), but accuracy decreased with increasing OSA severity, according to study findings.

Medicare beneficiaries with untreated obstructive sleep apnea (OSA) have increased healthcare utilization (HCU) and costs across all points of service, according to results of a recent study published by the Journal of Clinical Sleep Medicine.

Medical cannabis was found to exhibit an overall positive effect on maintaining nightime sleep in patients with chronic pain, but frequent use was associated with problems of both waking up at night and falling asleep, according to study findings.

Jazz Pharmaceuticals announced today it had redeemed its priority review voucher to submit a New Drug Application to the FDA on January 21, 2020; the company seeks approval for JZP-258, an investigational medication to treat cataplexy and excessive daytime sleepiness in patients 7 years and older with narcolepsy.

Along with weight loss, exercise, and nutrition, employers now target sleep improvements in employees; a Republican member of the FTC supports Medicare drug price negotiations; sepsis is likely responsible for 20% of deaths worldwide.

Sleep duration was found to reflect the profile of specific circulating microRNAs in the blood of school-aged children and adolescents, indicating the potential efficacy of a blood test to examine those at risk of negative health outcomes related to insufficient sleep, according to study findings.

Narcolepsy type 1 (NT1) may be caused by an autoimmune T-cell response to orexins and could be triggered by flu antigens, according to study findings.

People who regularly sleep less than 4 hours or more than 11 hours were found to be 2 to 3 times more likely to have pulmonary fibrosis compared with those who sleep for 7 hours a day, according to study results.

The researchers reported that aging brings degeneration of the circadian pacemaker, a progressive decline in melatonin output and decrease in rhythm amplitude which contributes to increasing sleep fragmentation and waking up earlier in the morning.

Water fluoride concentrations were associated with higher odds of reports of snorting, gasping, or stopping breathing while sleeping at night.

People who sleep 9 or more hours a day, take midday naps lasting more than 90 minutes, or have poor sleep quality may be at an increased risk of stroke, according to study findings.

Narcolepsy management should be a combination of behavioral and pharmacologic strategies that are tailored to the patient with consideration of the impact of symptoms and how they may evolve, according to a recent review aiming to improve narcolepsy diagnosis and management.

A regular sleep schedule may decrease obesity risks, says an Italian study.

This week, the top managed care stories included the White House seeking a truce between CMS Administrator Seema Verma and HHS Secretary Alex Azar; Sanofi will shift its focus from diabetes to cancer drugs; results highlight real-world evidence of chimeric antigen receptor T-cell therapies.

Results of the study indicated that irregular schedules, increased night shifts, sleep disturbances, and work hours were related to a higher burnout risk in police officers.

Modifiable lifestyle behaviors, such as physical activity, sleep time, television time, and diet, were shown to contribute to risk of obesity and cardiometabolic conditions in early childhood, according to study findings.

A recent review examined the challenges of treating excessive daytime sleepiness due to obstructive sleep apnea (OSA) and narcolepsy.

The association between disadvantaged communities and heightened risk of cardiovascular disease was attributed to factors that impair sleep quality and duration, such as living in noisy environments, working several jobs with various shifts, and having greater levels of emotional and financial stress, according to study findings.

Chronic opioid therapy was found to disrupt sleep and increase the risk of sleep disorders, while prescription drug use for pain and sleep exhibited an increased risk of frailty among users, according to 2 study findings stressing the need for heightened prescription education among providers for potential adverse risks.