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The Biden administration purchases an additional 200 million coronavirus disease 2019 (COVID-19) vaccine doses; the president plans to revoke Medicaid work requirements; companies seek billion-dollar tax deductions in opioid crisis settlement.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

This week, the top managed care news included President Biden’s DOJ reversing course in case seeking to overturn the Affordable Care Act; once-weekly semaglutide and lifestyle changes slashed body weight by 15%; updates on COVID-19 vaccines and treatments.

Carfilzomib-dexamethasone improved renal overall and complete response in patients with relapsed or refractory multiple myeloma (RRMM) compared with a regimen of bortezomib-dexamethasone in a real-world study.

A temporary switch from oral to intravenous (IV) selexipag is safe and well tolerated in the treatment of pulmonary arterial hypertension (PAH).

Compared with patients with Parkinson disease, rheumatoid arthritis, or epilepsy, those with multiple sclerosis exhibited higher rates of medication adherence throughout the first year of treatment.

A comparison of 2 time periods shows that following an initial decline, hospital admissions for primary management of heart failure rose between 2014 and 2017.

Abatacept was shown to have a 9% increase in likelihood of achieving remission compared with conventional therapy for rheumatoid arthritis (RA), which the researchers contribute to the treatment’s lower discontinuation rates.

CDC updates its guidance to reflect best mask-wearing practices; study highlights racial disparities in nursing home coronavirus disease 2019 (COVID-19) deaths; North Dakota to consider mandatory mental health studies in schools.

Humana and IBM Watson Health collaboration to streamline access to accurate information on benefits and health care costs for Humana employer group members, agents, and employers.

An investigation of 24 women from the United Kingdom’s PROTECTOR trial has revealed that their concerns toward cancer risk and menopause affect their choice of surgery as treatment for ovarian cancer.

Whereas patient care was often bogged down in bureaucracy when he was younger, Robert K. Massie Jr, PhD, MA, of the Society for Progress, notes that hospitals and caregivers are increasingly paying attention to what makes sense for patient care.

In the placebo-controlled trial, 86% of participants who received semaglutide attained at least a 5% reduction in total body weight.

The Department of Justice (DOJ), under a new administration, on Wednesday dropped its previous position that the now-defunct tax provision in the Affordable Care Act (ACA) cannot be severed from the rest of the law, thus making the entire health law unconstitutional.

Compared with pollen season in 1990, today's pollen season is starting earlier and lasting longer, largely because of human-caused climate change, researchers said.

The FDA approved a prescription tongue muscle stimulation device that claims to reduce mild sleep apnea and snoring in patients with obstructive sleep apnea.

Using optical coherence tomography, researchers found that length of disorganization of retinal inner layer, length of external ellipsoid zone disruption, and foveal avascular zone circularity were associated with visual impairment in treatment-naïve patients with diabetes.

Experts outlined the impact value-based insurance design (VBID) has had on the coronavirus disease 2019 (COVID-19) pandemic response and future potential applications of the model.

Significant differences in health characteristics may provide insight into why females are far more likely to suffer asthma than males

The FDA issues an emergency use authorization (EUA) for Eli Lilly’s coronavirus disease 2019 (COVID-19) treatment; insurance waivers for COVID-19–related costs are starting to expire; new data update convalescent plasma’s indication.

In a review published in Frontiers in Psychiatry, researchers outlined potential mechanisms accounting for comorbid bipolar disorder and migraine and examined therapeutic targets for treatment to improve prognosis in these patients.

House Democrats include a major expansion of Affordable Care Act (ACA) subsidies in their proposed coronavirus disease 2019 (COVID-19) relief package; differences between vaccine hesitancy and refusal are spotlighted; CanSino Biologics’ 1-shot vaccine is 65.7% effective against symptomatic COVID-19 cases.

On this episode of Managed Care Cast, we speak with experts from ChristianaCare, which implemented a diabetes pilot program at 4 of its primary care sites in 2019 and saw its population of patients with well-controlled disease grow by 16%.

Bayer and Orion corporation today announced the upcoming expansion of the global clinical development program for darolutamide (Nubeqa), an oral androgen receptor inhibitor for patients with prostate cancer.

Machine learning of data from 3 well-known heart studies shows a decline in heart failure risk from drinking at least 1 cup of caffeinated coffee each day.

Results of a longitudinal prospective case-control study found rates of retinal thinning were higher among individuals with sickle cell retinopathy compared with individuals without the condition.

An Apple Watch designed to remotely monitor fluctuations of resting tremor and dyskinesia in persons with Parkinson disease was shown to match in-clinic evaluations of these symptoms and capture symptom changes in response to treatment for 94% of participants.

Migraine is a potential risk factor for asthma and asthma is a potential risk indicator for migraine, authors of a systematic review and meta-analysis concluded.