Sarepta Therapeutics has started screening participants for a Phase 3 clinical trial to test its gene therapy candidate SRP-9003 in children with limb-girdle muscular dystrophy type 2E; wastewater testing points to a new COVID-19 infection wave fueled by the JN.1 variant; most patients on anti-obesity medications kept at least some weight off up to a year after they stopped taking them.
Global warming, wildfires, precipitation, floods, and storms impact patients with atopic dermatitis (AD).
The TROP-2–directed antibody drug conjugate is currently being investigated as a monotherapy and a combination therapy for non–small cell lung cancer (NSCLC) in 3 trials: phase 3 EVOKE-01, phase 2 EVOKE-02, and phase 3 EVOKE-03.
Momelotinib was given category 2A and 2B status for patients with high- and low-risk myelofibrosis (MF) and MF with anemia. However, ruxolitinib retains a higher category of recommendation as a treatment for patients with MF.
A recent cohort study finds that prenatal opioid exposure is associated with increased risk of certain immune-related conditions, including asthma.
Insomnia in patients undergoing hemodialysis was not found to be significantly affected by cognitive behavioral therapy for insomnia (CBT-I) or pharmacotherapy.
A new report compared the blood immune repertoires of patients with chronic lymphocytic leukemia (CLL) who received chemoimmunotherapy and those who received ibrutinib.
Results from a meta-analysis suggest a correlation between natural hair color and the development of skin cancer.
The researchers explained that their findings expanded upon evidence of the harmful respiratory effects of night shifts while also providing valuable evidence for the development of COPD prevention strategies.
People living with HIV reported feeling inferiority due to HIV and gloomy feelings during the COVID-19 pandemic, as researchers linked internalized HIV stigma to depressive symptoms.
Compared with a hemoglobin A1c (HbA1c) level of 5.5%, adolescents with overweight or obesity were 72 times more likely to have diabetes if their HbA1c was 6.3% to 6.4%.
Separate machine learning models were able to effectively predict both the length of hospital stay and the risk of prolonged hospitalization in people living with HIV.
The study, which pulled self-reported data from online bulletin boards across the US, Canada, and the United Kingdom in 2020, found that the degree of burden varied based on patient disease stage, among other factors.
Pharmaceutical companies required to update prescribing information for chimeric antigen receptor (CAR) T-cell therapies; Texas dashboard reports a 40% increase in pediatric flu cases; a blood test shows high accuracy for Alzheimer disease biomarkers.
In a cohort with more than half a million women with endometrial, ovarian, or cervical cancer, less than 1% were enrolled in a clinical trial, and more than 85% of enrolled women were White.
This new economic valuation of the societal and health care benefits of gene therapy to treat sickle cell disease (SCD) concludes the highly personalized treatment has potential to be cost effective if priced below $2 million.
A multidisciplinary approach is needed in patients with pulmonary arterial hypertension (PAH) who contract COVID-19, as they may experience worse outcomes.
Although ibrutinib adds to the cost of treatment, its benefits over the long term justify the cost, investigators found.
Meeting the 2024 deadline for an international agreement on pandemic response may not happen; the Biden administration announces measures to counter restrictive state laws on abortion; cervical cancer incidence declines as more women receive the human papillomavirus vaccine.
A real-world study conducted across 9 European countries found that bolus injection frequency and engagement with a smart pen to administer insulin were associated with improved glycemic control among young adult patients with type 1 diabetes (T1D).
People of color with scalp psoriasis experienced significant improvement in scalp itch and patient-reported health-related quality-of-life outcomes.
David Adamson, MD, emphasizes the need for continuous education and building relationships with colleagues to navigate the complexities of reproductive rights and evolving care standards.
Virtual reality (VR) combined with pulmonary rehabilitation was more effective than pulmonary rehabilitation alone in improving the pulmonary function, exercise capacity, and mental health of patients with chronic obstructive pulmonary disease (COPD).
Registered dietitian, Molly Kimball, RD, CSSD, of Ochsner Health, navigates cultural identity in diet changes for long-term success, in an interview.
A survey of pediatric dermatologists revealed that topical corticosteroids are the most common first-line treatment for children with alopecia areata, regardless of age or hair loss severity.
The study provides proof of principle for a novel approach to early detection of ovarian cancer based on an assessment of genomic instability patterns in DNA from Papanicolaou (Pap) smears.
Once treated with a one-size-fits-all approach, changes in the landscape for myasthenia gravis are allowing for more precise treatment of the disease.
The January 2024 guidelines update also changed mirvetuximab soravtansine plus bevacizumab from a category 2B recommendation to a category 2A recommendation for platinum-resistant, FRα-expressing tumors.
Researchers found that venetoclax, either alone or post treatment with a Bruton tyrosine kinase inhibitor (BTKi), was safe and effective for patients with chronic lymphocytic leukemia (CLL).
A single-center study suggests complement inhibitors do not reduce the severity of a COVID-19 Omicron infection in patients with paroxysmal nocturnal hemoglobinuria (PNH).
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